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pH comes from the term “power of Hydrogen”, or the hydrogen ion concentration present in a given solution. It helps to measure the acidity or alkalinity of a substance.

Researchers engineer stem cell with ‘suicide genes’ to induce cell death in all but beta cells

Researchers have been advancing methods to generate insulin-producing beta cells from pluripotent stem cells for the clinical treatment of type 1 diabetes.

20 Feb 2019

Novel preclinical model mimics persistent interneuron loss seen in preterm infants

Research-clinicians at Children's National Health System have created a novel preclinical model that mimics the persistent interneuron loss seen in preterm human infants, identifying interneuron subtypes that could become future therapeutic targets to prevent or lessen neurodevelopmental risks, the team reports Jan. 31, 2019, in eNeuro.

20 Feb 2019

T-cells play key role in how the body fights follicular lymphoma

Healthy white blood cells, called "T-cells," play a crucial role in how the body fights follicular lymphoma. That's according to the results of a study led by Mayo Clinic hematologists Zhi Zhang Yang, M.D., and Stephen Ansell, M.D., Ph.D., that was published in Cell Reports.

20 Feb 2019

New forms of older anti-cancer agent appear to enhance immune response to fight melanoma

Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins and the Johns Hopkins University School of Medicine report two new forms of an older anti-cancer agent they developed appear to enhance the immune system's ability to fight melanoma in mice.

20 Feb 2019

Study suggests new treatment strategy for deadly brain cancer

In a study of mice and human brain tumors researchers at the University of the Michigan, Ann Arbor, searched for new treatments by exploring the reasons why some patients with gliomas live remarkably longer than others.

19 Feb 2019

Multinational initiative to study familial primary distal renal tubular acidosis

In addition to regulating the body's fluid balance, by excreting greater or smaller amounts of urine, the kidneys also maintain the proper balance of electrolytes (salts) and the pH (an acid-base equilibrium) within our body.

19 Feb 2019

Female adolescent blood donors more likely to have iron deficiency and related anemia

Female adolescent blood donors are more likely to have low iron stores and iron deficiency anemia than adult female blood donors and nondonors, which could have significant negative consequences on their developing brains, a new study led by Johns Hopkins researchers suggests.

19 Feb 2019

Study finds neuromelanin-sensitive MRI as potential biomarker for psychosis

Researchers have shown that a type of magnetic resonance imaging -- called neuromelanin-sensitive MRI is a potential biomarker for psychosis.

18 Feb 2019

Study examines link between supply of primary care physicians and life expectancy

This study used U.S. population data to identify changes in the supply of primary care physicians across counties from 2005 to 2015 and the association with life expectancy and other outcomes.

18 Feb 2019

New study assesses screen time in young children

Children younger than 6 spend most of their screen time watching TV. That's the finding of a new study that assessed screen time in young children in 1997 and in 2014, before and after mobile devices were widely available.

18 Feb 2019

Scientists discover trigger that turns strep infections into devastating disease

Houston Methodist infectious disease scientists have discovered a previously unknown trigger that turns a relatively run-of-the-mill infection into a devastatingly ravenous, flesh-eating disease.

18 Feb 2019

Hormone therapy during gender transition may increase risk for cardiovascular events

Patients receiving hormone therapy as part of their gender-transition treatment had an elevated risk for cardiovascular events, including strokes, heart attacks and blood clots, according to a study published in the American Heart Association's journal Circulation.

18 Feb 2019

Combination of PARP inhibitor and immunotherapy results in tumor regression in SCLC mouse models

Researchers at The University of Texas MD Anderson Cancer Center have discovered that a combination of immune checkpoint blockade and targeted therapies that block normal DNA damage repair achieved significant tumor regression in mouse models of small cell lung cancer, suggesting a promising new approach for treating patients with this aggressive cancer.

18 Feb 2019

Study finds genetic vulnerability to use of menthol cigarettes

A genetic variant found only in people of African descent significantly increases a smoker's preference for cigarettes containing menthol, a flavor additive.

15 Feb 2019

MUSC researchers discover new mechanism for a class of anti-cancer drugs

Researchers at the Medical University of South Carolina reveal a novel binding site for a class of anti-cancer drugs known as E1 inhibitors. This finding could lead to the design of more efficient E1 inhibitors.

15 Feb 2019

Castration-resistant metastatic prostate cancer responds to combination of immune checkpoint inhibitors

Some patients with metastatic prostate cancer respond to a combination of immune checkpoint inhibitors after hormonal therapy and chemotherapy have failed, according to early results from a clinical trial led by investigators at The University of Texas MD Anderson Cancer Center presented today at the American Society of Clinical Oncology Genitourinary Cancers Symposium in San Francisco.

15 Feb 2019

Immune checkpoint molecule protects against future development of cancer

A research team at the University of Louisville has discovered that an immune checkpoint molecule they developed for cancer immunotherapy, also protects against future development of multiple types of cancer when administered by itself.

15 Feb 2019

New method for improved visualization of single-cell RNA- sequencing data

Like going from a pinhole camera to a Polaroid, a significant mathematical update to the formula for a popular bioinformatics data visualization method will allow researchers to develop snapshots of single-cell gene expression not only several times faster but also at much higher-resolution.

15 Feb 2019

Large-scale clinical trial begins to study liver transplantation between people with HIV

The first large-scale clinical trial to study liver transplantation between people with HIV has begun at clinical centers across the United States. The HOPE in Action Multicenter Liver Study will determine the safety of this practice by evaluating liver recipients for potential transplant-related and HIV-related complications following surgery.

15 Feb 2019

Moffitt researchers shed light on how CAR T cells function mechanistically

The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that activates a patient's own immune system to target cancer cells.

15 Feb 2019

pH News and Research

Further Reading

Researchers engineer stem cell with ‘suicide genes’ to induce cell death in all but beta cells

Novel preclinical model mimics persistent interneuron loss seen in preterm infants

T-cells play key role in how the body fights follicular lymphoma

New forms of older anti-cancer agent appear to enhance immune response to fight melanoma

Study suggests new treatment strategy for deadly brain cancer

Multinational initiative to study familial primary distal renal tubular acidosis

Female adolescent blood donors more likely to have iron deficiency and related anemia

Study finds neuromelanin-sensitive MRI as potential biomarker for psychosis

Study examines link between supply of primary care physicians and life expectancy

New study assesses screen time in young children

Scientists discover trigger that turns strep infections into devastating disease

Hormone therapy during gender transition may increase risk for cardiovascular events

Combination of PARP inhibitor and immunotherapy results in tumor regression in SCLC mouse models

Study finds genetic vulnerability to use of menthol cigarettes

MUSC researchers discover new mechanism for a class of anti-cancer drugs

Castration-resistant metastatic prostate cancer responds to combination of immune checkpoint inhibitors

Immune checkpoint molecule protects against future development of cancer

New method for improved visualization of single-cell RNA- sequencing data

Large-scale clinical trial begins to study liver transplantation between people with HIV

Moffitt researchers shed light on how CAR T cells function mechanistically

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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