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Employers can play key role in promoting better health: Report

As the U.S. continues to struggle with both cost and quality issues in an evolving health care system, employers can play a key role in promoting better health and more efficient use of resources, The Health Project reported this week.

17 Aug 2010

Deconstruction of biomedical research on pain will improve diagnosis, treatment of chronic pain sufferers

Is the science of diagnosing pain causing a number of pain sufferers to defend their honor? Research out of the University of Cincinnati is examining the diagnosis of pain that evades scientific testing, and the additional emotional suffering that can result for the patient.

17 Aug 2010

Simple, low-cost interventions reduce most common hospital-acquired infections

Urinary catheters are often left in place longer than needed, and new research shows that reminder systems that encourage hospital staff to remove catheters promptly can reduce the rate of catheter-associated urinary tract infections by 52 percent.

17 Aug 2010

NSF awards Georgia Institute of Technology $3 million for stem cell bio-manufacturing research program

The National Science Foundation (NSF) has awarded $3 million to the Georgia Institute of Technology to fund a unique research program on stem cell bio-manufacturing. The program is specifically focused on developing engineering methods for stem cell production, in order to meet the anticipated demand for stem cells. The award comes through the NSF's Integrative Graduate Education and Research Traineeship (IGERT) Program, which supports innovation in graduate education in fields that cross academic disciplines and have broad societal impact.

17 Aug 2010

Studies provide evidence for new approach to MRSA vaccines

Two recent studies provide evidence for a new approach to vaccines to prevent infections caused by drug-resistant Staphylococcus aureus -- better known as MRSA - the leading cause of skin and soft tissue, bloodstream and lung infections in the United States. One demonstrates a way to counteract the bacteria's knack for evading the immune system. The other shows how to disrupt the germ's tissue-damaging mechanism.

17 Aug 2010

Springer to publish ASENT's Neurotherapeutics journal

Beginning in 2011, Springer will publish Neurotherapeutics, the official Journal of the American Society for Experimental NeuroTherapeutics (ASENT). With the switch to Springer, Neurotherapeutics will change its format of publishing review articles only to offering original research articles as well. The journal achieved a debut Impact Factor of 5.38 in 2009, placing it in the top quartile of journals in both the Neurosciences and Pharmacology & Pharmacy categories.

17 Aug 2010

Human induced pluripotent stem cells help to treat Parkinson’s disease: Research

Researchers at the Buck Institute for Age Research have successfully used human induced pluripotent stem cells (iPSCs) to treat rodents afflicted with Parkinson's Disease (PD). The research, which validates a scalable protocol that the same group had previously developed, can be used to manufacture the type of neurons needed to treat the disease and paves the way for the use of iPSC's in various biomedical applications. Results of the research, from the laboratory of Buck faculty Xianmin Zeng, Ph.D., are published August 16, 2010 in the on-line edition of the journal Stem Cells.

17 Aug 2010

New DNA sequencing method can lead to effective individualized medicine

In experiments with potentially broad health care implications, a research team led by a University of Washington physicist has devised a method that works at a very small scale to sequence DNA quickly and relatively inexpensively.That could open the door for more effective individualized medicine, for example providing blueprints of genetic predispositions for specific conditions and diseases such as cancer, diabetes or addiction.

17 Aug 2010

Bariatric surgery can result in sustained reversal of obesity, type 2 diabetes: Study

Results of a large national study show that nearly three-quarters of obese patients with type 2 diabetes who undergo weight-loss surgery are able to stop insulin and other antidiabetes drugs within six months. In the Johns Hopkins study of insured, obese, diabetic patients, researchers also found that in the third year following surgery, average annual health care costs per patient decreased by more than 70 percent. The study is published in the Archives of Surgery this month.

17 Aug 2010

Revolutions Medical collaborates on clinical applications and validation process of MRI software tools

Revolutions Medical Corporation begins collaboration with H. Keith Brown, PhD, Philadelphia College of Osteopathic Medicine, on two clinical applications using their proprietary Magnetic Resonance software tools; RevDisplay, RevColor and Rev3D. One clinical application is for the differentiation and characterization of Intracranial Hemorrhages by Color MRI Automatic Segmentation and the other is for characterization of intracranial masses by Color MRI Automatic Segmentation.

17 Aug 2010

Human adult stem cells can regenerate damaged heart tissue: Research

Mayo Clinic investigators, with Belgian collaborators, have demonstrated that rationally "guided" human adult stem cells can effectively heal, repair and regenerate damaged heart tissue. The findings called "landmark work" in an accompanying editorial appear in today's Journal of the American College of Cardiology.

17 Aug 2010

Scientists identify possible therapeutic strategy for reducing leukemia risk from chemotherapy

A UCSF-led team has discovered at least one key reason why blood stem cells are susceptible to developing the genetic mutations that can lead to adult leukemia. Their finding also may explain, they say, why some other age-related hematological disorders develop.The study, reported in "Cell Stem Cell" and reviewed in Cell Stem Cell and Cell, opens a new frontier for studying the molecular underpinnings of adult leukemia.

17 Aug 2010

Researchers visualize ruptures of atherosclerotic plaques with multi-color CT and gold nanoparticles

Researchers from Mount Sinai School of Medicine have for the first time developed a way to visualize coronary artery plaques vulnerable to rupture using multi-color computed tomography (CT), an innovation that will lead to better and earlier diagnosis of cardiovascular disease. The data are published in the September issue of Radiology.

17 Aug 2010

Study finds abnormal expression of miRNAs can contribute to human diseases

Researchers at Tufts University School of Medicine and Tufts Medical Center have identified an RNA sequence that promotes increased numbers of specific microRNAs (miRNAs), molecules that regulate cell growth, development, and stress response. The discovery helps researchers understand the links between miRNA expression and disease, including heart disease and cancer. The findings are published in the August 13 issue of Molecular Cell.

17 Aug 2010

Scientists find epigenetic landscape map for tissue differentiation

Having charted the occurrence of a common chemical change that takes place while stem cells decide their fates and progress from precursor to progeny, a Johns Hopkins-led team of scientists has produced the first-ever epigenetic landscape map for tissue differentiation.The details of this collaborative study between Johns Hopkins, Stanford and Harvard appear August 15 in the early online publication of Nature.

17 Aug 2010

Albert Einstein College of Medicine named 1 of 5 Nathan Shock Centers

Albert Einstein College of Medicine of Yeshiva University has been named one of the National Institutes of Health's (NIH) Nathan Shock Centers of Excellence in the Basic Biology of Aging. The select group of five centers nationwide provides leadership in the pursuit of basic research into the biology of aging. Einstein's designation includes a $3.1 million, five-year grant from the NIH's National Institute on Aging.

17 Aug 2010

Non-viral gene therapy delays onset of eye disease

In one of only two studies of its kind, a study from researchers at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts demonstrates that non-viral gene therapy can delay the onset of some forms of eye disease and preserve vision. The team developed nanoparticles to deliver therapeutic genes to the retina and found that treated mice temporarily retained more eyesight than controls.

17 Aug 2010

Antidepressant alleviates depression in peri- and postmenopausal women: Study

An antidepressant can alleviate symptoms of major depression in women experiencing or about to experience menopause, according to a study released today led by a Virginia Commonwealth University researcher.

17 Aug 2010

Study reveals how galectin-3 carbohydrate-binding protein promotes angiogenesis

A new study describes how a carbohydrate-binding protein, galectin-3, promotes angiogenesis, the growth of new blood vessels. Targeting the protein, scientists identified two approaches that significantly reduced angiogenesis in mice. These discoveries, published online August 16 in The Journal of Experimental Medicine, may lead to novel treatments for diseases caused by excessive angiogenesis, including age-related macular degeneration, cancer, and diabetes.

16 Aug 2010

Medco Health Solutions to acquire United BioSource Corporation

Medco Health Solutions, Inc. and United BioSource Corporation today announced a definitive agreement under which Medco will acquire closely held UBC in an all-cash transaction valued at approximately $730 million. The combination of America's leading advanced pharmacy with one of the world's most respected sources of post-approval drug and device research extends Medco's core capabilities in data analytics and research to further accelerate pharmaceutical knowledge – advancing patient safety and furthering evidence-based medicine.

16 Aug 2010