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1 in 6 patients with colorectal cancer found to have inherited genetic mutations

A new Mayo Clinic study bolsters evidence that colorectal cancer is often imprinted in family genes and passed on from one generation to the next.

20 Apr 2021

Defects in specific goblet cells may be a factor contributing to ulcerative colitis

There are many variants of "goblet cells" in the intestines and they seem to have different functions, according to a new study from the University of Gothenburg.

19 Apr 2021

Three teams selected to receive the first awards from Dartmouth Innovations Accelerator for Cancer

Three teams of Dartmouth researchers have been selected to receive the first awards from the Dartmouth Innovations Accelerator for Cancer.

17 Apr 2021

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

Today, the U.S. Food and Drug Administration approved Opdivo (nivolumab), in combination with certain types of chemotherapy, for the initial treatment of patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer and esophageal adenocarcinoma.

16 Apr 2021

CU researcher receives NIH grant to analyze the link between gut microbiome and osteoarthritis

Osteoarthritis affects the joints, but according to researcher Michael Zuscik, PhD, it may start in the gut.

15 Apr 2021

Researchers map the changing trends of cancer burden worldwide and in China

Cancer is one of the leading causes of mortality worldwide, and the global burden of cancer continues to rise steadily and unchecked.

15 Apr 2021

Pigs’ brain size and digestive system are excellent analogs for human newborns

Before humans can benefit from new drug therapies and nutritional additives, scientists test their safety and efficacy in animals, typically mice and rats.

14 Apr 2021

ACE2 homology in laboratory and wild animals

A new preprint research paper posted to the bioRxiv server describes the conservation of an important receptor gene for the virus among several animal species that live in close contact or proximity to humans.

13 Apr 2021

FDA approves marketing of first AI-based device to assist clinicians during colon cancer screening

Today, the U.S. Food and Drug Administration authorized marketing of the GI Genius, the first device that uses artificial intelligence (AI) based on machine learning to assist clinicians in detecting lesions (such as polyps or suspected tumors) in the colon in real time during a colonoscopy.

9 Apr 2021

Study offers localized treatment direction for a cause of Crohn's disease

People with Crohn's disease are typically treated with powerful anti-inflammatory medications that act throughout their body, not just in their digestive tract, creating the potential for unintended, and often serious, side effects.

7 Apr 2021

New research could rescue failed immunotherapies for treating solid tumors

New research from the UVA Cancer Center could rescue once-promising immunotherapies for treating solid cancer tumors, such as ovarian, colon and triple-negative breast cancer, that ultimately failed in human clinical trials.

7 Apr 2021

Researchers explore link between intestinal microbiota with colon cancer in patients with Lynch Syndrome

The researcher Gabriela Debesa, member of the research group at Simbiosis led by Andrés Moya at the Foundation for the Promotion of Health and Biomedical Research of Valencia Region (Fisabio), studied the relationship of the intestinal microbiota with colon cancer in patients with Lynch Syndrome (a hereditary illness that predisposes the development of cancer) using tissue samples in formalin and conserved in paraffin.

6 Apr 2021

Mice study points to a promising treatment for relieving colitis pain without side effects

A targeted opioid that only treats diseased tissues and spares healthy tissues relieves pain from inflammatory bowel disease without causing side effects, according to new research published in the journal Gut.

31 Mar 2021

Microbiota-derived molecules do not change the entry or replication of SARS-CoV-2 in intestinal cells

A study conducted at the University of Campinas in the state of São Paulo, Brazil, shows that compounds produced by gut microbiota (bacteria and other microorganisms) during fermentation of insoluble fiber from dietary plant matter do not affect the ability of the novel coronavirus SARS-CoV-2 to enter and replicate in cells lining the intestines.

30 Mar 2021

Specific protein may prevent cancer cell death, increase cancer metastasis

One specific protein may be a master regulator for changing how cancer cells consume nutrients from their environments, preventing cell death and increasing the likelihood cancer could spread, a study from the University of Notre Dame has shown.

30 Mar 2021

Study reveals the structure of key enzyme that may advance cancer research

In order to develop more effective drugs against a range of cancers, researchers have been investigating the molecular structure of many diseased-linked enzymes in the body. An intriguing case in point is Taspase 1, a type of enzyme known as a protease.

30 Mar 2021

Long-term, regular use of baby aspirin may reduce risk of colorectal cancer death

Long-term, regular use of baby aspirin-;at least 15 times per month-;prior to a diagnosis of colorectal cancer (CRC) may reduce the risk of death from the disease by limiting the spread of cancerous tumors pre-diagnosis, according to a study led by Cedars-Sinai Cancer researchers.

29 Mar 2021

New imaging technique can better identify the presence of residual cancers in rectal tissues

Rectal cancer, along with colon cancer, is the third-most common type of cancer in the United States, and treatment and surgery greatly affect the quality of life of patients.

26 Mar 2021

High-fiber diet can significantly alter the gut microbiome and nutrient intake

A short-term intervention in daily fiber consumption can significantly alter the gut microbiome and nutrient intake, according to a study led by University of California, Irvine researchers. The research was recently published by the American Society for Microbiology.

26 Mar 2021

New study may shed light on inflammatory bowel disease

Researchers have found an unexpected synergy between a T-cell stimulatory protein -- the ICOS ligand -- and interleukin-10, an immunoregulatory cytokine, to prevent inflammatory bowel disease in mice.

26 Mar 2021

Colon News and Research

1 in 6 patients with colorectal cancer found to have inherited genetic mutations

Defects in specific goblet cells may be a factor contributing to ulcerative colitis

Three teams selected to receive the first awards from Dartmouth Innovations Accelerator for Cancer

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

CU researcher receives NIH grant to analyze the link between gut microbiome and osteoarthritis

Researchers map the changing trends of cancer burden worldwide and in China

Pigs’ brain size and digestive system are excellent analogs for human newborns

ACE2 homology in laboratory and wild animals

FDA approves marketing of first AI-based device to assist clinicians during colon cancer screening

Study offers localized treatment direction for a cause of Crohn's disease

New research could rescue failed immunotherapies for treating solid tumors

Researchers explore link between intestinal microbiota with colon cancer in patients with Lynch Syndrome

Mice study points to a promising treatment for relieving colitis pain without side effects

Microbiota-derived molecules do not change the entry or replication of SARS-CoV-2 in intestinal cells

Specific protein may prevent cancer cell death, increase cancer metastasis

Study reveals the structure of key enzyme that may advance cancer research

Long-term, regular use of baby aspirin may reduce risk of colorectal cancer death

New imaging technique can better identify the presence of residual cancers in rectal tissues

High-fiber diet can significantly alter the gut microbiome and nutrient intake

New study may shed light on inflammatory bowel disease

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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