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Study implicates gut microbiome and immune response in hospital-acquired infections

In a recent study published in the journal Nature Medicine, researchers at the University of Calgary analyzed the dynamics of fecal microbiota and conducted single-cell profiling of inflammatory responses and systemic immunity to determine associations between gut microbiome dysbiosis and an increased risk of nosocomial infections.

16 Mar 2023

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

In a Phase II trial led by researchers from The University of Texas MD Anderson Cancer Center, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC).

16 Mar 2023

Detecting tissue-resident memory T cells in solid tumors

In this interview, NewsMedical talks with Cerba Research about in situ multiplex analysis of regulatory and effector T cells in tumors.

16 Mar 2023

Immunochemistry multiplex for solid tumor analytical validation

In this interview, NewsMedical exchanges with Cerba on how to use T-regulatory immunochemsitry multiplex for solid tumor analytical validation.

From Cerba Research 16 Mar 2023

How to assess clinical response in multiple myeloma

In this interview, Cerba Research explains how its teams were able to assess clinical response in multiple myeloma (MM) patients that were receiving monoclonal antibodies treatment,

From Cerba Research 16 Mar 2023

Achieving immune cell checkpoint profiling

NewsMedical exchanges with Cerba Research on how to achieve immune cell checkpoint profiling of solid tumors by multiplex immunofluorescence.

From Cerba Research 16 Mar 2023

Creating more effective and safe treatments for COVID-19

When approaching a task, members of a team need to work in synergy. Nothing can be accomplished if you're pulling in different directions.

16 Mar 2023

Stimulus-sensitive polymeric micelles show promise for future targeted drug delivery and chemotherapy

Researchers documented the various polymeric materials that can be used to synthesize micelles, which can then be used for targeted cancer therapy by tailoring the micelles to respond to stimuli.

16 Mar 2023

Scientists develop genetically defined mouse models for multiple myeloma subtypes

A team of scientists led by Martin Janz and Klaus Rajewsky at the Max Delbrück Center has successfully generated genetically defined mouse models for two subtypes of multiple myeloma.

16 Mar 2023

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

Researchers assessed the efficiency of a genetic decoding system for diagnosing non-small cell lung cancer (NSCLC).

16 Mar 2023

Multivariate brain-wide associated studies can be replicable with substantially smaller sample sizes

Since the development of functional magnetic resonance imaging in the 1990s, the reliance on neuroimaging has skyrocketed as researchers investigate how fMRI data from the brain at rest, and anatomical brain structure itself, can be used to predict individual traits, such as depression, cognitive decline, and brain disorders.

16 Mar 2023

Global maternal Strep B immunization program may save millions of dollars in healthcare costs

A global maternal immunization program for group B Streptococcus - Strep B - would save millions of dollars in healthcare costs by reducing death and disability, a team led by researchers from the London School of Hygiene & Tropical Medicine has found.

16 Mar 2023

Phase 2 clinical trial investigates the effectiveness of innovative procedure to control Type 2 diabetes

More than 37 million Americans have diabetes, and approximately 90-95% have Type 2 diabetes.

16 Mar 2023

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Acute gastroenteritis afflicts adults of all ages, causing significant suffering and inflicting significant costs on the American healthcare system.

16 Mar 2023

AI-based drug interaction prediction technology analyzes the interaction between Paxlovid ingredients

KAIST (President Kwang Hyung Lee) announced on the 16th that an advanced AI-based drug interaction prediction technology developed by the Distinguished Professor Sang Yup Lee's research team in the Department of Biochemical Engineering that analyzed the interaction between the PaxlovidTM ingredients that are used as COVID-19 treatment and other prescription drugs was published as a thesis.

16 Mar 2023

Albumedix and Heartseed announce Recombumin® as a critical excipient in the manufacture of Heartseed's HS-001 investigational cell therapy as its first in-human trial commences

Albumedix Ltd, Nottingham, United Kingdom, now part of the global life science group Sartorius, and Heartseed Inc ('Heartseed'), Tokyo, Japan, Tuesday 14th March 2023, announce that Recombumin® is a critical component of Heartseed's HS-001, an investigational cardiac remuscularization cell therapy which has commenced first in human dosing.

From Albumedix Ltd. 16 Mar 2023

Medicine News and Research

Study implicates gut microbiome and immune response in hospital-acquired infections

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

Detecting tissue-resident memory T cells in solid tumors

Immunochemistry multiplex for solid tumor analytical validation

How to assess clinical response in multiple myeloma

Achieving immune cell checkpoint profiling

Creating more effective and safe treatments for COVID-19

Stimulus-sensitive polymeric micelles show promise for future targeted drug delivery and chemotherapy

Scientists develop genetically defined mouse models for multiple myeloma subtypes

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

Multivariate brain-wide associated studies can be replicable with substantially smaller sample sizes

Global maternal Strep B immunization program may save millions of dollars in healthcare costs

Phase 2 clinical trial investigates the effectiveness of innovative procedure to control Type 2 diabetes

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

AI-based drug interaction prediction technology analyzes the interaction between Paxlovid ingredients

Albumedix and Heartseed announce Recombumin® as a critical excipient in the manufacture of Heartseed's HS-001 investigational cell therapy as its first in-human trial commences

The US remains a grim leader in preterm births. Why? And can we fix it?

Study: Black Americans lost trust in cancer information given out by the government during the pandemic

Physical exercise programs tend to be easier to stick with when prescribed via mobile digital devices

Life expectancy in the UK falls down the global ranks, analysis shows

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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