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UAB study shows missense mutations as key risk factor for severe symptoms of neurofibromatosis type 1

Research led by Ludwine Messiaen, Ph.D., professor of genetics at the University of Alabama at Birmingham, shows that missense mutations in a cluster of just five codons in the NF1 gene are an important risk factor for severe symptoms of the genetic disease neurofibromatosis type 1.

28 Dec 2017

Researchers reveal how tumor cells disrupt circadian rhythm to survive

Tumor cells use the unfolded protein response to alter circadian rhythm, which contributes to more tumor growth, Hollings Cancer Center researchers at the Medical University of South Carolina find.

28 Dec 2017

$Study uncovers genomic targets in refractory neuroblastoma$

Study uncovers genomic targets in refractory neuroblastoma

Neuroblastoma (NB) is the most common solid tumor found in children. It starts in some very early forms of nerve cells found in the embryo or fetus.

28 Dec 2017

Reduced activity of transcription factor plays key role in triggering pulmonary fibrosis

To date, the molecular basis of pulmonary fibrosis has been poorly understood. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now shown that reduced activity of the transcription factor FoxO3 plays a key role in the development of the disease.

26 Dec 2017

Novel GammaPod system receives FDA clearance to treat early stage breast cancer

The GammaPod - a first-of-its kind stereotactic radiotherapy system to treat early stage breast cancer - has received 510(k) clearance from the U.S. Food and Drug Administration, paving the way for the manufacturer to bring the system to market for the treatment of breast cancer patients.

26 Dec 2017

Nanobiotix receives FDA approval for first immuno-oncology trial

NANOBIOTIX, a late clinical-stage nanomedicine company pioneering new approaches to the treatment of cancer, today announced the U.S. Food and Drug Administration has approved its Investigational New Drug Application for NBTXR3, a first-in-class nanoparticle designed for direct injection into cancerous tumors, activated by stereotactic ablative radiotherapy (SABR) and administered in combination with an anti-PD1 antibody (nivolumab or pembrolizumab).

26 Dec 2017

Novartis announces FDA approval of its first and only CML therapy with TFR data in product label

Novartis announced today that the US Food and Drug Administration (FDA) approved the inclusion of Treatment-free Remission (TFR) data in the Tasigna® (nilotinib) US product label.

26 Dec 2017

Novel radiotherapy system receives FDA clearance for treating early stage breast cancer

The GammaPod – a first-of-its kind stereotactic radiotherapy system to treat early stage breast cancer – has received 510(k) clearance from the U.S. Food and Drug Administration, paving the way for the manufacturer to bring the system to market for the treatment of breast cancer patients.

22 Dec 2017

Researchers sequence salamander genome to reveal unique features of regeneration

Researchers at Karolinska Institutet in Sweden have managed to sequence the giant genome of a salamander, the Iberian ribbed newt, which is a full six times greater than the human genome.

22 Dec 2017

New method sifts through millions of molecular targets to find precise tumor beacon

By screening millions of molecular targets, researchers have uncovered a tumor beacon detected by the immune cells of two patients with colorectal cancer.

22 Dec 2017

Proton therapy center for treating cancer patients coming to Utah

A new cancer treatment technology is one step closer to Salt Lake City. Today Huntsman Cancer Institute at the University of Utah announced a plan to add a proton therapy center to its Cancer Hospital.

22 Dec 2017

Study suggests new target to treat prostate cancer

Hokkaido University researchers have uncovered a cellular protein that stabilizes a tumor promoting signaling pathway, suggesting a new target to treat prostate cancer.

22 Dec 2017

Study finds new marker to detect fatal breast cancer

A new study conducted at the University College London, UK, found a new marker that has the capacity to help diagnose fatal breast cancer up to one year earlier than existing methods.

22 Dec 2017

Higher ‘mutational burden’ of tumors predicts success rate with cancer immunotherapies

The "mutational burden," or the number of mutations present in a tumor's DNA, is a good predictor of whether that cancer type will respond to a class of cancer immunotherapy drugs known as checkpoint inhibitors, a new study led by Johns Hopkins Kimmel Cancer Center researchers shows.

21 Dec 2017

Specific diets may help prevent colorectal cancer in high-risk groups

Colorectal cancer is the most prevalent malignant tumor in Spain. It is known that factors such as diet and intestinal inflammation play an important role in its occurrence, but direct links between nutrients, inflammation and colorectal cancer are poorly described.

21 Dec 2017

Medicaid expansion improves early-stage cancer detection, research shows

The Affordable Care Act led to an increase in the number of cancer diagnoses -- particularly those at early stages -- in states where Medicaid was expanded, according to research from Indiana University.

21 Dec 2017

Tumor growth traits can influence response to cancer drugs, study finds

Individual tumors respond differently to cancer drugs, if at all. Until now, it remained a mystery why tumors have different reactions to the exact same therapy. But a new study at the USC Viterbi School of Engineering finds that tumor growth properties can influence response to cancer drugs.

21 Dec 2017

Tumor News and Research

UAB study shows missense mutations as key risk factor for severe symptoms of neurofibromatosis type 1

Researchers reveal how tumor cells disrupt circadian rhythm to survive

Study uncovers genomic targets in refractory neuroblastoma

Reduced activity of transcription factor plays key role in triggering pulmonary fibrosis

Novel GammaPod system receives FDA clearance to treat early stage breast cancer

Nanobiotix receives FDA approval for first immuno-oncology trial

Novartis announces FDA approval of its first and only CML therapy with TFR data in product label

Novel radiotherapy system receives FDA clearance for treating early stage breast cancer

Researchers sequence salamander genome to reveal unique features of regeneration

New method sifts through millions of molecular targets to find precise tumor beacon

Proton therapy center for treating cancer patients coming to Utah

Study suggests new target to treat prostate cancer

Study finds new marker to detect fatal breast cancer

Higher ‘mutational burden’ of tumors predicts success rate with cancer immunotherapies

Specific diets may help prevent colorectal cancer in high-risk groups

Medicaid expansion improves early-stage cancer detection, research shows

Tumor growth traits can influence response to cancer drugs, study finds

Loss of specific protein makes breast cancers more aggressive, resistant to chemotherapy

Novel drug shows promise in treating metastatic kidney cancer

Nanomedicine platform can guide doctors to remove tumors and kill malignant cells

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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