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New definitions can specify high-risk comorbidity combinations for older surgical patients

A new way to identify more specific, higher-risk groups of older surgical patients can help in clinical decision-making and accurately comparing the performance of one hospital to another, according to research published in the Journal of the American College of Surgeons.

16 Mar 2023

Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

The gut is home to a cast of microbes that influence health and disease. Some types of microorganisms are thought to contribute to the development of inflammatory conditions, such as inflammatory bowel disease (IBD), but the exact cascade of events that leads from microbes to immune cells to disease remains mysterious.

16 Mar 2023

Artificial pancreas technology improves blood glucose control in young children with type 1 diabetes

Artificial pancreas technology improved blood glucose control in young children between ages 2 and 5 with type 1 diabetes, according to the results of the Pediatric Artificial Pancreas (PEDAP) Trial, a 13-week randomized controlled trial conducted at three pediatric diabetes centers across the United States.

15 Mar 2023

Dementia risk is reduced by a Mediterranean diet

A new study in the journal BMC Medicine aimed to analyze the association between dementia incidence and MedDiet adherence as well as assess the interaction between genetic risk and diet for dementia.

15 Mar 2023

Study focuses on new approach that delivers a "one-two punch" to help T cells attack solid tumors

A new approach that delivers a "one-two punch" to help T cells attack solid tumors is the focus of a preclinical study by researchers from the Perelman School of Medicine at the University of Pennsylvania.

15 Mar 2023

Johns Hopkins’ ARISE program may increase the odds of home discharge for hospitalized COVID-19 patients

The Acute Hospital Rehabilitation Intensive Service (ARISE) program, developed in 2020 by the Johns Hopkins Department of Physical Medicine and Rehabilitation (PM&R), may increase the chances of patients hospitalized with COVID-19 getting discharged to their home rather than to a rehabilitation facility that provides post-hospitalization care services.

15 Mar 2023

Premature infants in incubators absorb evaporated alcohol from alcohol-based disinfectants

Neonatal incubators are considered the first home of infants born prematurely, keeping them warm and protecting them from possible infections.

15 Mar 2023

Scientists generate 3D ultra-resolution maps of mitochondrial networks in lung tumors

Scientists have long known that mitochondria, the "powerhouses" of cells, play a crucial role in the metabolism and energy production of cancer cells.

15 Mar 2023

Study demonstrates long-term safety and clinical benefit of combination therapy for cystic fibrosis

Patients with cystic fibrosis (CF) face difficulty breathing and a decline in lung function and are at risk of early death. CF is an inherited condition that results in thick mucus build-up, persistent infection and inflammation in the lungs.

15 Mar 2023

Vitamin A-rich diet may reduce risk of developing asparaginase-associated pancreatitis in ALL patients

Consuming a diet rich in vitamin A or its analogs may help prevent children and young adults with acute lymphoblastic leukemia (ALL) reduce their risk of developing painful pancreas inflammation during chemotherapy treatment.

15 Mar 2023

Smoking cessation drug may help people stop using cocaine while in treatment for OUD

For some people receiving methadone for treatment of opioid use disorder (OUD), the co-use of opioids and stimulants such as cocaine is an issue.

15 Mar 2023

Point-of-care test identifies patients who may benefit from hypnosis interventions for pain treatment

Hypnosis is an effective treatment for pain for many individuals but determining which patients will benefit most can be challenging. Hypnotizability testing requires special training and in-person evaluation rarely available in the clinical setting.

15 Mar 2023

Researchers shine new light on a potential target for the treatment of diabetic nephropathy

The kidneys perform a critical role in the body by removing waste and excess fluid in the form of urine. In a condition known as diabetic nephropathy, complications from diabetes disrupt the ability of the kidneys to function properly.

15 Mar 2023

Research uncovers a possible explanation for sex differences in pancreatic cancer

Immunotherapy is an effective form of therapy for different types of cancer. However, for pancreatic cancer, its effect is limited and differs between men and women.

15 Mar 2023

Researchers design a virus-resistant, more useful E. coli bacteria

In a step forward for genetic engineering and synthetic biology, researchers have modified a strain of Escherichia coli bacteria to be immune to natural viral infections while also minimizing the potential for the bacteria or their modified genes to escape into the wild.

15 Mar 2023

Medicine News and Research

New definitions can specify high-risk comorbidity combinations for older surgical patients

Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

Artificial pancreas technology improves blood glucose control in young children with type 1 diabetes

Dementia risk is reduced by a Mediterranean diet

Study focuses on new approach that delivers a "one-two punch" to help T cells attack solid tumors

Johns Hopkins’ ARISE program may increase the odds of home discharge for hospitalized COVID-19 patients

Premature infants in incubators absorb evaporated alcohol from alcohol-based disinfectants

Scientists generate 3D ultra-resolution maps of mitochondrial networks in lung tumors

Study demonstrates long-term safety and clinical benefit of combination therapy for cystic fibrosis

Vitamin A-rich diet may reduce risk of developing asparaginase-associated pancreatitis in ALL patients

Smoking cessation drug may help people stop using cocaine while in treatment for OUD

Point-of-care test identifies patients who may benefit from hypnosis interventions for pain treatment

Researchers shine new light on a potential target for the treatment of diabetic nephropathy

Research uncovers a possible explanation for sex differences in pancreatic cancer

Researchers design a virus-resistant, more useful E. coli bacteria

Research identifies western diet-induced microbial and metabolic contributors to liver disease

Researchers identify a potential treatment to prevent severe COVID-19 in high-risk patients

Higher plasma caffeine levels may reduce adiposity and risk of type 2 diabetes

Newly identified small molecule may help treat people with drug-resistant epilepsy

Reversing infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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