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Family members who do not carry inherited mutation have higher risk of melanoma

In families who carry certain inherited mutations that increase the risk for melanoma, members who do not carry the mutation also have an increased risk of melanoma, a study from Karolinska Institutet published in Genetics in Medicine reports.

8 Dec 2017

New first line combination therapy shows promising results in patients with advanced NSCLC

A new combination therapy for the first line treatment of advanced non-squamous non-small-cell lung cancer (NSCLC) improves progression-free survival (PFS), according to results of phase III IMpower150 trial presented at the ESMO Immuno Oncology Congress 2017.

7 Dec 2017

Study paves way for new therapeutic strategies to impede growth of virus-induced cancers

Researchers at the Cancer Science Institute of Singapore at the National University of Singapore have identified a novel molecular pathway by which a tumor suppressor, TIP60, inhibits the growth of cancer cells.

7 Dec 2017

Fusobacterium may play role in colon cancer growth, study finds

Like nomads who carry tokens of home on their travels, colorectal cancer cells that spread to other parts of the body appear to bring several of the species of bacteria that were their companions in the colon, Dana-Farber Cancer Institute scientists report in a new study in the journal Science.

7 Dec 2017

New 3D-printed artificial models mimic the look and feel of real organs

A team of researchers led by the University of Minnesota has 3D printed lifelike artificial organ models that mimic the exact anatomical structure, mechanical properties, and look and feel of real organs. These patient-specific organ models, which include integrated soft sensors, can be used for practice surgeries to improve surgical outcomes in thousands of patients worldwide.

6 Dec 2017

Brazilian researchers identify genes linked to melanoma progression

When researchers at the University of São Paulo in Brazil treated human melanoma cell lines with a synthetic compound similar to curcumin, one of the pigments that give turmeric its orange color, they identified genes with altered expression in potentially invasive tumors and malignant cells resistant to chemotherapy.

6 Dec 2017

Study shows how interplay between two key enzymes promotes brain tumor growth

Study results revealed previously unknown interplay between two key enzymes and a novel understanding of how brain cancer tumors form and spread, according to researchers at The University of Texas MD Anderson Cancer Center.

6 Dec 2017

High ADAR1 enzyme levels correlate with reduced survival rates in multiple myeloma

Multiple myeloma is the second most common blood cancer in the United States. Thirty to 50 percent of multiple myeloma patients have extra copies of the gene that encodes the enzyme ADAR1.

6 Dec 2017

Researchers unravel novel mechanism of estrogen action on heart physiology

Estrogens are powerful hormones important for the formation and function of the nervous, reproductive and cardiovascular systems.

6 Dec 2017

TUM scientists discover emergency shut-off switch for T cell Non-Hodgkin's lymphoma

Safety switches that automatically stop the device for example before it overheats are built into many electrical appliances. Cells are also equipped with such "emergency stop" functions. They make sure that a defective cell doesn't become a tumor cell.

6 Dec 2017

New study describes unique bioengineered tissue construct for modeling colorectal cancer

A new study describes a unique bioengineered tissue construct, or organoid, into which colorectal cancer cells are embedded, creating a model of the tumor and surrounding extracellular matrix.

6 Dec 2017

Immune-boosting drug combination may hold promise for treating ovarian cancer

Johns Hopkins Kimmel Cancer Center researchers demonstrated that mice with ovarian cancer that received drugs to reactivate dormant genes along with other drugs that activate the immune system had a greater reduction of tumor burden and significantly longer survival than those that received any of the drugs alone.

5 Dec 2017

Scientists reveal ‘anti-metastatic surveillance’ role of Caveolin-1 protein

A new study conducted at the VIB-KU Leuven Center for Cancer Biology in Belgium has labeled the protein Caveolin-1 as a high-potential pursuit in the fight against cancer.

5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

Cancer therapies are designed to kill tumor cells, but produce tumor cell debris in the process. In a study published in The Journal of Experimental Medicine, researchers from Brigham and Women's Hospital and colleagues show that leftover debris can stimulate inflammation and tumor growth, but that molecules called resolvins can block that unwanted inflammatory response.

5 Dec 2017

Scientists investigate new role of old protein in breast cancer

Scientists led by Dr Chris Toseland of the University's School of Biosciences studied a protein called Myosin VI, a molecular motor which acts as a courier to transport other proteins within our cells.

4 Dec 2017

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Children with an extremely deadly form of brain cancer might benefit from a new treatment that aims to direct an immune response against an abnormally shaped protein found exclusively on cancer cells, according to a new study led by UC San Francisco researchers.

4 Dec 2017

Study reveals gene linked to metastatic melanoma

A study by Craig J. Ceol, PhD, assistant professor of molecular medicine at the University of Massachusetts Medical School, has revealed a protein active during early embryo development called GDF6 plays a primary role in metastatic melanoma.

4 Dec 2017

Innovative technique makes low-grade gliomas visible

Gliomas are a type of brain tumor characterized by a poor prognosis. In order to improve this prognosis, as much of the tumor as possible must be removed safely during the neurosurgical operation.

4 Dec 2017

UC San Diego researchers receive nearly $8 million grant for new stem cell-based AML treatments

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine unanimously approved yesterday two grants worth a total of almost $8 million to University of California San Diego School of Medicine researchers investigating novel stem cell-based treatments for acute myeloid leukemia or AML.

4 Dec 2017

Tumor News and Research

Family members who do not carry inherited mutation have higher risk of melanoma

New first line combination therapy shows promising results in patients with advanced NSCLC

Study paves way for new therapeutic strategies to impede growth of virus-induced cancers

Fusobacterium may play role in colon cancer growth, study finds

New 3D-printed artificial models mimic the look and feel of real organs

Brazilian researchers identify genes linked to melanoma progression

Study shows how interplay between two key enzymes promotes brain tumor growth

High ADAR1 enzyme levels correlate with reduced survival rates in multiple myeloma

Researchers unravel novel mechanism of estrogen action on heart physiology

TUM scientists discover emergency shut-off switch for T cell Non-Hodgkin's lymphoma

New study describes unique bioengineered tissue construct for modeling colorectal cancer

Immune-boosting drug combination may hold promise for treating ovarian cancer

Scientists reveal ‘anti-metastatic surveillance’ role of Caveolin-1 protein

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

Scientists investigate new role of old protein in breast cancer

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Study reveals gene linked to metastatic melanoma

Innovative technique makes low-grade gliomas visible

UC San Diego researchers receive nearly $8 million grant for new stem cell-based AML treatments

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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