Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

$4.5 million contract to develop heart assist devices for infants

The University of Pittsburgh's McGowan Institute for Regenerative Medicine has been awarded a five-year $4.5 million contract from the National Heart, Lung, and Blood Institute to develop a heart assist device for infants.

28 Apr 2004

$11 million for lung injury research

Northwestern University has received an $11 million Program Project Grant (PPG) from the National Institutes of Health to define the mechanisms that cause changes in the alveolar epithelium during lung injury.

27 Apr 2004

BioTime awarded a research grant for blood plasma volume expander

BioTime, Inc. has announced that it has been awarded a research grant by the National Heart, Lung, and Blood Institute division of the National Institutes of Health (NIH) for use in the development of its HetaCool® blood plasma volume expander following peer review.

27 Apr 2004

Injections of adult stem cells could repair hearts

Injections of adult stem cells into damaged heart tissue significantly improved heart function in patients with severe congestive heart failure, according to results of the first prospective randomized trial of the experimental therapy presented today at the American Association for Thoracic Surgery.

26 Apr 2004

Cardiac Intensive Care Unit lowest heart attack rates in the state of Texas

That’s because the CICU he runs has the lowest myocardial infarction (heart attack) mortality in the entire South Texas region. It has one of the lowest rates in the state of Texas.

23 Apr 2004

CellCept linked to reduced cancer incidence

A study presented today at an international transplant meeting showed that heart transplant patients treated with the immunosuppressant CellCeptÒ (mycophenolate mofetil) in standard immunosuppressive regimens had a significantly lower risk of developing cancer compared to those receiving non-CellCept-based treatment regimens.

23 Apr 2004

Socially deprived individuals are 44% more likely to develop heart failure

Socially deprived individuals are 44% more likely to develop heart failure but 23% less likely to see their general practitioner on a regular basis compared with affluent patients, finds new research available on bmj.com.

22 Apr 2004

Marker predicts patients who are seven times more likely to die after suffering a heart attack

Researchers at Brigham and Women’s Hospital (BWH) have found a protein in the blood that may one day produce a simple and inexpensive test to help determine who is at high risk for problems following a heart attack.

22 Apr 2004

Study is first to see such changes in women without high blood pressure or other diseases

Young obese women who are otherwise healthy have hearts that exhibit changes in structure and function similar to those of hypertensive patients, which may help explain links between obesity and heart failure risk, according to a new study in the April 21, 2004 issue of the Journal of the American College of Cardiology.

20 Apr 2004

Coronary stent drives Johnson & Johnson to record profits

Johnson & Johnson today announced sales for the first quarter of $11.6 billion, an increase of 17.7% over the prior year. The increase represented operational growth of 12.3% and a currency impact of 5.4%. Domestic sales were up 15.1%, while international sales increased 21.8%, including operational growth of 7.8% and a positive currency impact of 14.0%.

13 Apr 2004

Gene therapy helps damaged heart cells regain strength and beat normally

Researchers at Jefferson Medical College and Duke University have used gene therapy to help damaged heart cells regain strength and beat normally again in the laboratory. The work takes the scientists one step closer to eventual clinical trials in humans.

12 Apr 2004

Unique heart arrhythmia drug represents one of the first molecular-based therapies for heart failure

Heart researchers at Columbia University Medical Center have developed and tested a unique heart arrhythmia drug that could prevent the sudden death of millions of people with heart failure as well as people with an inherited heart disorder. The drug represents one of the first molecular-based therapies for heart failure and avoids the toxicity of current treatments.

8 Apr 2004

Oral sildenafil improved exercise tolerance, cardiac output and quality of life in 22 patients with primary pulmonary hypertension

Oral sildenafil (Viagra®) improved exercise tolerance, cardiac output and quality of life in 22 patients with primary pulmonary hypertension, according to the results of the first randomized, placebo-controlled, double-blind, crossover study, reported in the April 7, 2004 issue of the Journal of the American College of Cardiology.

6 Apr 2004

Alzheimer's live about half as long as those of similar age without dementia

Age, seriousness of impairment, and the severity of other medical conditions are important indicators of how long an individual might survive after an Alzheimer's disease diagnosis, Eric B. Larson, M.D., M.P.H. and colleagues report in the April 6 Annals of Internal Medicine. Study authors include Linda Teri, Ph.D., recipient of an Alzheimer's Association $1 million Pioneer research grant.

6 Apr 2004

Study Identifies Predictors of Alzheimer's Disease Longevity

It's among the first questions asked after someone is diagnosed with Alzheimer's disease: "What can we expect?" It's a tough question that has been difficult to answer. But a new study suggests that assessing several key clinical aspects of the disease soon after diagnosis could help families and physicians better predict long-term survival in individuals with AD.

6 Apr 2004

Implantable defibrillator cuts heart attack risk of sudden death by 31%

Researchers at Loyola University Health System, Maywood, Ill., and the University of Rochester Medical Center, Rochester, N.Y., found that the previously demonstrated survival benefit of ICDs following a heart attack can last up to 15 years.

5 Apr 2004

Growth factor protein succeeds in growing new coronary arteries

Three patients of the UC Heart & Vascular Center have grown new coronary artery branches to increase blood flow to the heart after receiving a new growth factor protein (FGF1) in November 2003. All three patients showed improved blood flow to the heart twelve weeks following the injection.

26 Mar 2004

New Drug Offers Hope For Advanced Colorectal Cancer

Patients with advanced colorectal cancer have new hope for a longer life. The Food and Drug Administration recently approved the drug Avastin to be used in combination with chemotherapy. Doctors are calling it a big breakthrough.

22 Mar 2004

Heart Failure News and Research

Further Reading

$4.5 million contract to develop heart assist devices for infants

$11 million for lung injury research

BioTime awarded a research grant for blood plasma volume expander

Injections of adult stem cells could repair hearts

Cardiac Intensive Care Unit lowest heart attack rates in the state of Texas

CellCept linked to reduced cancer incidence

Socially deprived individuals are 44% more likely to develop heart failure

Marker predicts patients who are seven times more likely to die after suffering a heart attack

Study is first to see such changes in women without high blood pressure or other diseases

Coronary stent drives Johnson & Johnson to record profits

Gene therapy helps damaged heart cells regain strength and beat normally

Unique heart arrhythmia drug represents one of the first molecular-based therapies for heart failure

Oral sildenafil improved exercise tolerance, cardiac output and quality of life in 22 patients with primary pulmonary hypertension

Alzheimer's live about half as long as those of similar age without dementia

Study Identifies Predictors of Alzheimer's Disease Longevity

Implantable defibrillator cuts heart attack risk of sudden death by 31%

Growth factor protein succeeds in growing new coronary arteries

New Drug Offers Hope For Advanced Colorectal Cancer

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