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Poorly designed clinical trials adversely affect medical advances

In a paper published this week in Science, experts caution that important ethical issues in the testing of new therapies like stem cells may not be receiving the attention they deserve. Carnegie Mellon University's Dr. Alex John London (Dept. of Philosophy) joined McGill University's Dr. Jonathan Kimmelman (Faculty of Medicine) and University of Wisconsin-Madison's Marina Emborg (Dept. of Medical Physics) to examine the way scientists, physicians, and regulators evaluate risk and benefit when testing new drugs in human beings for the first time.

14 May 2010

Measuring gene expression in healthy women may predict future breast cancer risk, say scientists

Researchers at Georgetown Lombard Comprehensive Cancer Center have been able to show, in mice, how just a little adjustment in the expression of two common genes can promote the kind of cellular changes that led to breast cancer. They say these tweaks likely mimic natural variation women have in expression of the two genes.

14 May 2010

Phase 2a study results of Aerosurf for prevention of RDS in premature infants published

Discovery Laboratories, Inc., announces the publication of results from its previously-conducted Phase 2a feasibility study of Aerosurf, the Company's aerosolized KL4 surfactant, for the prevention of respiratory distress syndrome in premature infants, in the May 2010 issue of the Journal of Aerosol Medicine and Pulmonary Drug Delivery in the study titled "An Open Label, Pilot Study of Aerosurf Combined with nCPAP to Prevent RDS in Preterm Neonates".

14 May 2010

Scientists to discuss opportunities and challenges for combating HIV, TB

As alarms sound about a weakening international commitment to global AIDS, scientists will gather in Washington, DC to report on potentially transformative new tools in the battle against this deadly epidemic. US policy is moving backwards at a time when the science is more promising than ever.

14 May 2010

11 leading medical societies support Health Care Truth and Transparency Act of 2010

As the United States prepares to add 32 million more patients to the health care system through health care reform, 11 of the leading medical societies in the country joined together today to publicly support the introduction of the Health Care Truth and Transparency Act of 2010.

14 May 2010

NanoViricides signs research and development agreement with Dr. Ken S. Rosenthal's laboratory

NanoViricides, Inc., reports that it has signed a research and development agreement with Dr. Ken S. Rosenthal's laboratory at Northeastern Ohio Universities Colleges of Medicine and Pharmacy.

14 May 2010

Study examines impact of tobacco smoke carcinogen on mice

Although tobacco use is widely understood to be one of the leading causes of oral cancer, research on the prevention of tobacco-related oral cancer in experimental animals has traditionally been limited to examining the impact of synthetic carcinogens manufactured especially for cancer research, rather than on observing the effects of carcinogens that occur in tobacco smoke.

14 May 2010

Study examines long-term economic consequences of childhood psychological disorders

A first-of-its-kind study examining the long-term economic consequences of childhood psychological disorders finds the conditions diminish people's ability to work and earn as adults, costing $2.1 trillion over the lifetimes of all affected Americans.

14 May 2010

RMEI, PIM sponsor continuing education series on castration-resistant prostate cancer

Castration-resistant prostate cancer (CRPC), defined as tumor progression despite castrate levels of testosterone, develops in many prostate cancer patients treated with androgen-deprivation therapy. Current treatment regimens are complicated by toxicities and a low rate of relapse-free survival. Many novel therapies in clinical trials offer hope for patients with this challenging diagnosis. Healthcare professionals who are treating CRPC must stay abreast of these emerging therapies to ensure optimal care for these patients.

14 May 2010

Experts address fundamental questions related to renal failure in ICU

Despite the fact that recent medical advances have allowed healthcare professionals to stabilize patients who would have otherwise died, many stabilized patients later develop organ system failure. In fact, acute renal failure is one of the biggest threats to critically ill patients: forty percent of patients with this condition die.

14 May 2010

SPIROCOR's RSR non-invasively measures presence of significant coronary artery disease

Newly published data confirm a non-invasive Respiratory Stress Response (RSR) can quickly and accurately measure the presence of significant coronary artery disease (sCAD), the leading cause of cardiovascular death worldwide. Patients in the study with sCAD had a lower RSR compared to patients without.

14 May 2010

Stanford researchers make hair-cell-like cells in a petri dish

Deep inside the ear, specialized cells called hair cells detect vibrations in the air and translate them into sound. Ten years ago, Stefan Heller, PhD, professor of otolaryngology at the Stanford University School of Medicine, came up with the idea that if you could create these cells in the laboratory from stem cells, it would go a long way toward helping scientists understand the molecular basis of hearing in order to develop better treatments for deafness.

14 May 2010

Mauna Kea Technologies' Cellvizio improves diagnosis of early forms of bile duct cancer

New data from a multi-centric international registry study show that cellular-level imaging with Mauna Kea Technologies' Cellvizio®, the world's smallest microscope, appears to significantly improve a physician's ability to diagnose or rule out early forms of bile duct cancer during a standard endoscopic diagnostic exam.

14 May 2010

Medical professionals meet to standardize CT scanning techniques

A national summit of medical professionals meeting last month in Atlanta called for the creation of consensus scan techniques as a way of addressing the concerns of patients undergoing CT scans -- a common medical imaging procedure that uses X-rays to show cross-sectional images of the body.

14 May 2010

Prometheus announces novel method for early detection of HACA during infliximab treatment

Prometheus Laboratories Inc., a specialty pharmaceutical and diagnostic company, announced a new method for detecting antibody levels in individual patients treated with infliximab, a biologic therapy that has been used to treat more than a million patients across a number of autoimmune diseases, including rheumatoid arthritis, Crohn's disease and ulcerative colitis.

14 May 2010

ISCA recommends chromosomal microarray as new standard for genetic evaluation of children

An international consortium of genetics experts has issued a consensus statement recommending chromosomal microarray (CMA) as the new standard practice for genetic evaluation of children with unexplained developmental delay, autism or birth defects.

14 May 2010

FREEDOM trial results to be presented at Heart Rhythm 2010

St. Jude Medical, Inc., a global medical device company, today announced results of the FREEDOM trial during the late breaking clinical trial presentations at Heart Rhythm 2010, the Heart Rhythm Society's 31st Annual Scientific Sessions. The trial demonstrated that the QuickOpt optimization feature available in St. Jude Medical cardiac resynchronization therapy devices produces an equivalent response rate in CRT patients as optimization using echocardiography.

14 May 2010

Johns Hopkins Children's Center neonatologist joins NQF HIT advisory committee

Johns Hopkins Children's Center neonatologist Christoph Lehmann, M.D., has joined the nation's leading watchdog organization on health-care quality, the National Quality Forum (NQF), as a member of its newly formed Health Information Technology (HIT) advisory committee.

14 May 2010

Rotavirus vaccination associated with decline in U.S. hospitalization rates for acute gastroenteritis: Study

Vaccinating infants against rotavirus, a leading cause of severe diarrhea and dehydration among babies and young children, was associated with a dramatic decline in U.S. hospitalization rates for acute gastroenteritis.

14 May 2010

Neurologix reports lower net loss of $3.5M for first-quarter 2010

Neurologix, Inc., a biotechnology company developing innovative gene therapies for the brain and central nervous system, today announced its financial results for the quarter ended March 31, 2010.

14 May 2010

Medicine News and Research

Poorly designed clinical trials adversely affect medical advances

Measuring gene expression in healthy women may predict future breast cancer risk, say scientists

Phase 2a study results of Aerosurf for prevention of RDS in premature infants published

Scientists to discuss opportunities and challenges for combating HIV, TB

11 leading medical societies support Health Care Truth and Transparency Act of 2010

NanoViricides signs research and development agreement with Dr. Ken S. Rosenthal's laboratory

Study examines impact of tobacco smoke carcinogen on mice

Study examines long-term economic consequences of childhood psychological disorders

RMEI, PIM sponsor continuing education series on castration-resistant prostate cancer

Experts address fundamental questions related to renal failure in ICU

SPIROCOR's RSR non-invasively measures presence of significant coronary artery disease

Stanford researchers make hair-cell-like cells in a petri dish

Mauna Kea Technologies' Cellvizio improves diagnosis of early forms of bile duct cancer

Medical professionals meet to standardize CT scanning techniques

Prometheus announces novel method for early detection of HACA during infliximab treatment

ISCA recommends chromosomal microarray as new standard for genetic evaluation of children

FREEDOM trial results to be presented at Heart Rhythm 2010

Johns Hopkins Children's Center neonatologist joins NQF HIT advisory committee

Rotavirus vaccination associated with decline in U.S. hospitalization rates for acute gastroenteritis: Study

Neurologix reports lower net loss of $3.5M for first-quarter 2010

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