Lymph Node News and Research

RSS

Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

Neoprobe achieves accrual goal in Lymphoseek Phase 3 study in breast cancer/melanoma

Neoprobe Corporation, a diversified developer of innovative oncology surgical and diagnostic products, today announced that a multi-center Phase 3 study of Lymphoseek® has enrolled clinical subjects to achieve the minimum analysis goal of 196 lymph nodes, the study's primary accrual objective.

14 Feb 2011

Vaccinating through salivary glands may provide protection against wide range of diseases

If you don't like shots or needles, you're in luck. New research published online in The FASEB Journal gives the development of new oral vaccinations a shot in the arm thanks to discoveries involving the salivary glands of mice. In addition, this research report also offers a tantalizing glimpse of vaccines that could prevent infection at mucosal surfaces, even if direct injections into the body fail to cause immunity. This technique may be effective for a wide range of diseases from influenza to cholera.

11 Feb 2011

Photodynamic therapy could be useful in eradicating tumor-associated lymphatic vessels

Tumor cells have several routes that enable them to move from the primary tumor to distant tissues, a process called metastasis. It is metastasis of the primary tumor that kills most cancer patients. One of the least studied routes of metastasis is the lymphatic system. Many tumors produce factors that promote the formation of new lymphatic vessels (lymphangiogenesis).

10 Feb 2011

Study finds breast cancer patients do not benefit from axillary lymph node dissection

Among patients with early-stage breast cancer that had spread to a nearby lymph node and who received treatment that included lumpectomy and radiation therapy, women who just had the sentinel lymph node removed did not have worse survival than women who had more extensive axillary lymph node dissection, according to a study in the February 9 issue of JAMA.

9 Feb 2011

Four-gene/protein signature more accurately predicts metastatic prostate cancer

Prostate tumors that carry a "signature" of four molecular markers have the potential to become dangerously metastatic if not treated aggressively, researchers at Dana-Farber Cancer Institute report in a study published online today by the journal Nature. The discovery lays the groundwork for the first gene-based test for determining whether a man's prostate cancer is likely to remain dormant within the prostate gland, or spread lethally to other parts of the body.

3 Feb 2011

Microbubble contrast- enhanced ultrasound improves identification of sentinel lymph node in breast biopsies

Using "microbubbles" and ultrasound can mean more targeted breast biopsies for patients with early breast cancer, helping to determine treatment and possibly saving those patients from undergoing a second breast cancer surgery, a new study in shows.

2 Feb 2011

Surge of mosquito borne disease in South Australia following wet weather

Rising water in the Murray River has caused a surge in mosquito-borne infections in South Australia. The water is rising in the Murray in SA as floodwaters move downstream from the eastern states.

2 Feb 2011

FDA approves 'Cornell Dots' for first clinical trial in humans to diagnose cancer

"Cornell Dots" - brightly glowing nanoparticles - may soon be used to light up cancer cells to aid in diagnosing and treating cancer. The U.S. Food and Drug Administration has approved the first clinical trial in humans of the new technology.

1 Feb 2011

FDA approves ultrasmall silica inorganic nanoparticle INDA for targeted molecular imaging of cancer

Researchers at Memorial Sloan-Kettering Cancer Center's Nanotechnology Center, along with collaborators at Cornell University and Hybrid Silica Technologies, have received approval for their first Investigational New Drug Application from the US Food and Drug Administration for an ultrasmall silica inorganic nanoparticle platform for targeted molecular imaging of cancer, which may be useful for cancer treatment in the future.

31 Jan 2011

FDA reports possible association between breast implants, ALCL

The U.S. Food and Drug Administration reported on January 26 that "a possible association between saline and silicone gel-filled breast implants and anaplastic large cell lymphoma, a very rare type of cancer. Data reviewed by the FDA suggests that patients with breast implants may have a very small, but significant risk, of ALCL in the scar capsule adjacent to the implant.

29 Jan 2011

Gene signature can accurately predict breast cancer outcomes

Researchers from McGill University's Rosalind and Morris Goodman Cancer Research Centre, the Research Institute of the McGill University Health Centre, the Dana-Farber Cancer Institute and Harvard Medical School have discovered a gene signature that can accurately predict which breast cancer patients are at risk of relapse, thereby sparing those who are not from the burdens associated with unnecessary treatment.

28 Jan 2011

U.S. FDA announces link between breast implants and ALCL

The U.S. Food and Drug Administration today announced a possible association between saline and silicone gel-filled breast implants and anaplastic large cell lymphoma, a very rare type of cancer.

27 Jan 2011

New gene test can predict tumor spread in bladder cancer patients

Cancer scientists have designed the first molecular test to predict which bladder cancer patients may have cancer involvement in their lymph nodes at the time of surgery-which could help doctors determine which patients are good candidates for pre-surgical, or neo-adjuvant, chemotherapy.

21 Jan 2011

Study demonstrates prognostic value of DiagnoCure's Previstage GCC Colorectal Cancer Staging Test

DiagnoCure Inc., a life sciences company commercializing high‐value cancer diagnostic tests and delivering lab services, today announced positive initial results of a multi-center clinical study of 241 stage II colon cancer patients, a population categorized as low risk by traditional methods yet with an average recurrence rate of 20%.

20 Jan 2011

Preoperative Breast MRI accurately detects otherwise occult cancer

The use of preoperative Breast MRI detects otherwise occult cancer with a relatively high degree of accuracy when applied to a diverse population of patients newly diagnosed with breast cancer, according to a study in the January issue of the American Journal of Roentgenology.

13 Jan 2011

Common rubber products can cause contact allergy: Study

Common rubber products can form isothiocyanates in contact with skin and cause contact allergy. This is the conclusion of research carried out at the University of Gothenburg. Isothiocyanates are a group of reactive substances that are potent contact allergens.

12 Jan 2011

Elevated rates of 'Sarcoid Like' Granulomatous Pulmonary Disease found in WTC responders

Mount Sinai researchers coordinating the largest clinical study to date of "Sarcoid Like" Granulomatous Pulmonary Disease in World Trade Center (WTC) responders have found that the rate of the condition was increased in this group as compared to the records of pre-9/11 FDNY personnel. The study is published online in the American Journal of Industrial Medicine.

7 Jan 2011

Breast cancer survival techniques for dealing with challenges on the job and in life

As Lecheler celebrates the New Year, she is sharing her breast cancer survival techniques with business executives and others who are looking for a resolution they can keep - having a healthier and happier 2011. Lecheler offers up her integrated healing tips in her new book The Spirit to Heal.

28 Dec 2010

Patients with over expression of P-Rex1 protein are more likely to develop cancer metastasis

Overexpression or hyperactivation of ErbB cell-surface receptors drives the growth of many breast cancers. Drugs, like Herceptin, that block the receptors' signals halt tumor progression in some patients.

23 Dec 2010

Researchers discover protein that suppresses melanoma progression

In a breakthrough that could lead to new treatments for patients with malignant melanoma, researchers from Mount Sinai School of Medicine have discovered that a particular protein suppresses the progression of melanoma through regulation of an oncogene, or gene responsible for cancer growth. The study is published in the December 23 issue of Nature.