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Study identifies slowly proliferating and highly invasive melanoma cells

A study conducted at The Wistar Institute has led to the identification of a slowly proliferating and highly invasive melanoma cell subpopulation, characterized by production of a protein associated with invasive behavior. The research was published in the journal Oncogene.

21 Sep 2017

Study opens new door to potential treatments for highly lethal brain tumors

New research conducted in mice provides evidence that highly lethal brain tumors, called high-grade gliomas, stop growing when deprived of a specific molecule naturally produced when brain cells fire.

21 Sep 2017

UConn Health makes new 3D-printed model of arteries to help surgeons get practice

The first time a young surgeon threads a wire through a stroke victim's chest up through their neck and fishes a blood clot out of their brain may be one of the most harrowing moments in her career.

21 Sep 2017

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

University of Maryland School of Medicine researchers are investigating a new approach to treat high-risk soft-tissue sarcomas by combining two immunotherapy drugs with radiation therapy to stimulate the immune system to destroy the main tumor as well as leftover microscopic cancer cells that may seed other tumors.

20 Sep 2017

Poliovirus therapy triggers longer-lasting immune response against malignant tumors

An investigational therapy using modified poliovirus to attack cancer tumors appears to unleash the body's own capacity to fight malignancies by activating an inflammation process that counter's the ability of cancer cells to evade the immune system.

20 Sep 2017

Penn researchers identify new way to target enzyme crucial to tumor growth, develop new drugs

Opening up a new pathway to fight cancer, researchers at the University of Pennsylvania have found a way to target an enzyme that is crucial to tumor growth while also blocking the mechanism that has made past attempts to target that enzyme resistant to treatment.

20 Sep 2017

Inactivation of Capicua gene leads to formation of T-ALL tumors in mice, researchers find

Researchers at the Spanish National Cancer Research Centre have discovered a genetic alteration that is directly involved in at least 10% of cases of one of the most common cancers in children, T-cell acute lymphoblastic leukemia.

20 Sep 2017

Researchers propose new treatment strategy for colon cancer patients

Colorectal cancer is the fourth leading cause of cancer-related deaths worldwide. In a new study, researchers demonstrate for the first time that a previously uncharacterized protein is increased in colon cancer. The protein is immunoglobulin containing proline rich receptor-1 (IGPR-1) which was recently identified in the same laboratory as a cell adhesion molecule.

20 Sep 2017

Researchers identify role of tumor-infiltrating B-cells in melanoma progression, resistance to therapy

In a multi-institutional collaborative study, scientists at The Wistar Institute and the Medical University of Vienna, Austria, have identified the role of tumor-infiltrating or tumor-associated B-cells ("TABs") in melanoma progression and resistance to targeted therapy.

20 Sep 2017

Researchers develop new model to better simulate blood brain barrier for study of diseases

Scientists have helped provide a way to better understand how to enable drugs to enter the brain and how cancer cells make it past the blood brain barrier. The brain is protected by the near-impermeable blood brain barrier, a fortress which protects the brain but which also prevents the treatment of brain diseases, including brain tumors.

19 Sep 2017

Cholesterol-like molecules act as ‘cut-off’ switch for engine that powers cancer-killing cells

Scientists have just discovered how the engine that powers cancer-killing cells functions. Crucially, their research also highlights how that engine is fuelled and that cholesterol-like molecules, called oxysterols, act as a "cut-off" switch making it hard for our 'Natural Killer' cells to win the war against cancer.

19 Sep 2017

Salk study shows how fast-growing tumors evade immune system

The immune system automatically destroys dysfunctional cells such as cancer cells, but cancerous tumors often survive nonetheless. A new study by Salk scientists shows one method by which fast-growing tumors evade anti-tumor immunity.

18 Sep 2017

Cancer-fighting cells destroy tumors more effectively after being starved for oxygen

Mountain climbers and endurance athletes are not the only ones to benefit from altitude training - that is, learning to perform well under low-oxygen conditions.

18 Sep 2017

Research shows how bacteria inactivate common drug used to treat cancers

To the reasons that chemotherapy sometimes does not work, we can now add one more: bacteria. In a study published today in Science, researchers describe findings that certain bacteria can be found inside human pancreatic tumors.

18 Sep 2017

EPFL scientists discover metabolic differences between hepatoblastoma subtypes

Hepatoblastoma is a rare pediatric liver cancer, usually diagnosed in the first three years of life. Histological methods are used to distinguish between the different subtypes of hepatoblastoma.

18 Sep 2017

Combination of anti-malarial drug and photosensitizer could effectively kill cancer cells

Artemisinin, a potent anti-malarial drug, has been widely hailed as a promising alternative cancer treatment. Scientists from the National University of Singapore recently showed that its anti-cancer properties could be enhanced by 10 folds when used in combination with Aminolaevulinic acid, a photosensitizer or a drug which, upon exposure to light, leads to generation of free radicals that can kill cells.

18 Sep 2017

Study: Genomic profiling could help identify effective treatments for pediatric gliomas

The largest genomic profiling study ever conducted into a type of brain tumor known as glioma in children has identified genetic alterations in 96% of cases. As reported in The Oncologist, this genetic information could help to identify the most effective treatments for specific cases of glioma, hopefully improving the prognosis for what is currently the leading cause of death for children with cancer in the US.

18 Sep 2017

Heidelberg researchers gain new insights into formation of blood vessels

New insights into the development of the vascular system: researchers in the team of Dr Carmen Ruiz de Almodóvar of the Heidelberg University Biochemistry Center have discovered a crucial biological step that regulates the formation of blood vessels.

15 Sep 2017

Simple blood test provides new treatment choices to lung cancer patients

A simple test which can detect gene mutations in tumour DNA from blood samples is giving new choices to lung cancer patients with faster diagnosis and improved access to life changing drugs.

15 Sep 2017

BWH researchers identify new rare genetic cause of peritoneal mesothelioma

Mesothelioma is a rare and aggressive tumor that, in many cases, results from exposure to asbestos. But over the last several decades, other causes of the disease have emerged, including treatment with high-intensity therapeutic radiation and, more recently, an inherited genetic mutation.

14 Sep 2017

Tumor News and Research

Study identifies slowly proliferating and highly invasive melanoma cells

Study opens new door to potential treatments for highly lethal brain tumors

UConn Health makes new 3D-printed model of arteries to help surgeons get practice

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

Poliovirus therapy triggers longer-lasting immune response against malignant tumors

Penn researchers identify new way to target enzyme crucial to tumor growth, develop new drugs

Inactivation of Capicua gene leads to formation of T-ALL tumors in mice, researchers find

Researchers propose new treatment strategy for colon cancer patients

Researchers identify role of tumor-infiltrating B-cells in melanoma progression, resistance to therapy

Researchers develop new model to better simulate blood brain barrier for study of diseases

Cholesterol-like molecules act as ‘cut-off’ switch for engine that powers cancer-killing cells

Salk study shows how fast-growing tumors evade immune system

Cancer-fighting cells destroy tumors more effectively after being starved for oxygen

Research shows how bacteria inactivate common drug used to treat cancers

EPFL scientists discover metabolic differences between hepatoblastoma subtypes

Combination of anti-malarial drug and photosensitizer could effectively kill cancer cells

Study: Genomic profiling could help identify effective treatments for pediatric gliomas

Heidelberg researchers gain new insights into formation of blood vessels

Simple blood test provides new treatment choices to lung cancer patients

BWH researchers identify new rare genetic cause of peritoneal mesothelioma

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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