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Step-by-step process of rewiring cells to generate germ cell precursors

Different cell types-;say, heart, liver, blood, and sperm cells-;possess characteristics that help them carry out their unique jobs in the body.

21 Feb 2023

First molecular biomarker for acquired generalized lipodystrophy discovered

Researchers at UT Southwestern Medical Center have discovered the first molecular biomarker for acquired generalized lipodystrophy (AGL), a rare disorder in which fat deposits are destroyed, causing patients to have dangerously low body fat, signs of accelerated aging, and severe metabolic diseases including diabetes and fatty liver.

21 Feb 2023

Mapping specialized receptors on mosquito nerve cells reveals why the insects are more attracted to some humans

In a bid to understand why mosquitoes may be more attracted to one human than another, Johns Hopkins Medicine researchers say they have mapped specialized receptors on the insects' nerve cells that are able to fine-tune their ability to detect particularly "welcoming" odors in human skin.

21 Feb 2023

Review: Latest findings in the spina bifida-related care of many comorbidities

Open spina bifida (SB), a neural tube defect (NTD), also known as myelomeningocele, remains the most complex congenital abnormality of the central nervous system compatible with long term survival.

21 Feb 2023

Two new zebrafish models for studying the most common cause of Leigh syndrome developed

Researchers from Children's Hospital of Philadelphia (CHOP) developed two new zebrafish models for studying a specific genetic form of mitochondrial disease that represents the most common cause of Leigh syndrome.

21 Feb 2023

Oxford-Harrington Rare Disease Centre hosts virtual event in honor of the upcoming Rare Disease Day

The Oxford-Harrington Rare Disease Centre, a partnership of the University of Oxford and Harrington Discovery Institute at University Hospitals, is hosting a virtual event on Monday, Feb. 27, 2023, in honor of the upcoming Rare Disease Day, which is celebrated across the globe on February 28 every year.

21 Feb 2023

Black patients more likely to experience premature arteriovenous graft failure after dialysis maintenance

Compared to other races, African American patients are more likely to experience premature arteriovenous (AV) graft failure in the treatment of advanced kidney failure, according to a study published today in Radiology, a journal of the Radiological Society of North America.

21 Feb 2023

The impact of specific comorbidities and overall multimorbidity on the three mechanistically distinct phases of COVID-19

Researchers studied the impact of comorbidities in the three distinct phases of COVID-19.

21 Feb 2023

Adverse muscle composition can predict mortality risk in people with fatty liver disease

Obesity and a sedentary lifestyle contribute to an increasing number of people developing fatty liver disease.

21 Feb 2023

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Once thought incapable of encoding proteins due to their simple monotonous repetitions of DNA, tiny telomeres at the tips of our chromosomes seem to hold a potent biological function that's potentially relevant to our understanding of cancer and aging.

21 Feb 2023

Adipose-targeted delivery of thyroid hormone alleviates hypercholesterolemia and atherosclerosis

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has developed thyroid hormone (TH) - encapsulated nanoparticles modified with adipose-homing peptide, which selectively transport TH to adipose tissues.

20 Feb 2023

Use of dapivirine vaginal ring during third trimester of pregnancy poses no safety concerns

A vaginal ring containing the antiretroviral drug dapivirine posed no safety concerns when used in the third trimester of pregnancy, according to results to date from the first study of the dapivirine ring during pregnancy and one of only a few studies of an HIV prevention product in pregnant cisgender women.

20 Feb 2023

Structure of DREADD designer receptor could pave the way for creating next generation tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells.

20 Feb 2023

Research reveals regional differences in the spread of Japan's two main ancestral groups

Regional differences in the spread of Japan's two main ancestral groups have been revealed, thanks to new research at the University of Tokyo.

20 Feb 2023

Brexanolone inhibits key systemic inflammatory pathways associated with post-partum depression

Post-partum depression (PPD) develops after childbirth and affects both the mother's and the infant's health by preventing healthy bonding.

20 Feb 2023

Doxycycline taken after sex does not prevent bacterial STIs among cisgender women

Researchers from the University of Washington (UW), Kenya Medical Research Institute (KEMRI), and Hennepin Healthcare Research Institute (HHRI) announced results at CROI from a clinical trial demonstrating that doxycycline taken after sex does not prevent bacterial sexually transmitted infections (STIs) – chlamydia or gonorrhea – among cisgender women.

20 Feb 2023

Ketamine appears to hold promise in treating cocaine-use disorders

As cocaine use continues to climb across the United States, scientists have struggled to develop an effective pharmacological approach to treat the devastating disorder.

20 Feb 2023

Spinal cord stimulation technology instantly improves arm and hand mobility in stroke patients

A neurotechnology that stimulates the spinal cord instantly improves arm and hand mobility, enabling people affected by moderate to severe stroke to conduct their normal daily activities more easily, report researchers from the University of Pittsburgh and Carnegie Mellon University today in Nature Medicine.

20 Feb 2023

E-cigarettes as a first-line aid for smoking cessation in adults

Should electronic cigarettes, or vapes, be accepted more widely as an effective and respected tool for treating adult smokers’ nicotine addiction?

20 Feb 2023

COVID-19 vaccination associated with fewer heart attacks, strokes, and other cardiovascular issues

Analyzing the most extensive datasets in the United States, researchers from the Icahn School of Medicine at Mount Sinai have revealed that vaccination against COVID-19 is associated with fewer heart attacks, strokes, and other cardiovascular issues among people who were infected with SARS-CoV-2, the virus that causes COVID-19.

20 Feb 2023

Medicine News and Research

Step-by-step process of rewiring cells to generate germ cell precursors

First molecular biomarker for acquired generalized lipodystrophy discovered

Mapping specialized receptors on mosquito nerve cells reveals why the insects are more attracted to some humans

Review: Latest findings in the spina bifida-related care of many comorbidities

Two new zebrafish models for studying the most common cause of Leigh syndrome developed

Oxford-Harrington Rare Disease Centre hosts virtual event in honor of the upcoming Rare Disease Day

Black patients more likely to experience premature arteriovenous graft failure after dialysis maintenance

The impact of specific comorbidities and overall multimorbidity on the three mechanistically distinct phases of COVID-19

Adverse muscle composition can predict mortality risk in people with fatty liver disease

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Adipose-targeted delivery of thyroid hormone alleviates hypercholesterolemia and atherosclerosis

Use of dapivirine vaginal ring during third trimester of pregnancy poses no safety concerns

Structure of DREADD designer receptor could pave the way for creating next generation tools

Research reveals regional differences in the spread of Japan's two main ancestral groups

Brexanolone inhibits key systemic inflammatory pathways associated with post-partum depression

Doxycycline taken after sex does not prevent bacterial STIs among cisgender women

Ketamine appears to hold promise in treating cocaine-use disorders

Spinal cord stimulation technology instantly improves arm and hand mobility in stroke patients

E-cigarettes as a first-line aid for smoking cessation in adults

COVID-19 vaccination associated with fewer heart attacks, strokes, and other cardiovascular issues

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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