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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Short international trips can lead to spread of colistin resistance

The emergence of antibiotic resistance among dangerous pathogens is increasingly problematic worldwide. Many strains of infectious bacteria have become multidrug-resistant, and cannot be treated with common antibiotic therapies.

11 Apr 2018

Researchers discover how 'junk DNA' plays key role in holding the genome together

Researchers at the University of Michigan Life Sciences Institute and the Howard Hughes Medical Institute have determined how satellite DNA, considered to be "junk DNA," plays a crucial role in holding the genome together.

11 Apr 2018

Transcription factor Sp7 found to play key role in tooth development

Amjad Javed, Ph.D., and University of Alabama at Birmingham colleagues have found a key role in tooth development for the transcription factor Specificity protein 7, or Sp7.

11 Apr 2018

Biomarker panel can guide future therapeutic decisions for glioma patients

In an article published April 10th in the journal Cell Reports, researchers at the University of São Paulo describe a biomarker panel that could tell physicians which patients diagnosed with glioma, a type of brain cancer, will tend to progress to a more aggressive form of the disease in the event of relapse.

10 Apr 2018

Newly discovered predictive biomarkers could help assess level of glioma recurrence risk

Researchers have identified specific predictive biomarkers that could help assess the level of risk for recurrence in patients with malignant glioma. The study, led by Henry Ford Health System's Department of Neurosurgery and Department of Public Health Sciences, was published today in Cell Reports.

10 Apr 2018

New class of drug holds potential to help patients with treatment-resistant cancers

Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies.

10 Apr 2018

DNA test method can help quickly prevent Legionnaires' outbreak

A DNA test method called polymerase chain reaction allowed New York City health officials to identify the source of a Legionnaires' disease outbreak within hours of specimen collection and should be considered in all Legionnaires' outbreak investigations, researchers say in the April issue of the Journal of Environmental Health.

10 Apr 2018

Finding new drug target for common form of lung cancer

Research by Rutgers Cancer Institute of New Jersey investigators has identified novel functions of the superoxide dismutase 1 (SOD1) enzyme providing support that it could serve as a therapeutic target in the most common type of lung cancer.

10 Apr 2018

Removal of single mitochondrial protein leads to severe inflammation

The link between mitochondria and inflammation is still unclear. But it is known is that, for example, the accumulation of defective mitochondria, which should have been removed, causes inflammation.

10 Apr 2018

New technique makes it possible to trace lineage of each cell

Every biology textbook states that cells are life's building blocks. But researchers are only now beginning to understand their diversity. Technologies such as RNA sequencing are revealing which genes are expressed in each individual cell.

9 Apr 2018

UCLA researchers tweak CRISPR to accelerate genomic editing

The powerful gene-editing tool, CRISPR, has revolutionized research by allowing scientists to snip and patch DNA with remarkable precision. But tracking the impact of these changes on gene function can be time-consuming. Researchers currently analyze each edit one at a time, a process that can take weeks.

9 Apr 2018

Oxidative stress due to lack of tumor suppressor gene promotes cancer progression, study shows

Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore have identified that RUNX3, a tumour suppressor gene absent in many cancer types, acts as a barrier against oxidative stress in cancer cells.

9 Apr 2018

Novel biomarker helps optimize anticancer therapy

Researchers have identified a biomarker that can be used to visualize blood vessel activity and optimize the timing of anticancer therapy.

9 Apr 2018

Vascular stabilization biomarker helps optimize timing of anticancer therapies

Angiogenesis, the formation of new blood vessels, is essential for tumor growth. A new study reported in The American Journal of Pathology describes a vascular stabilization biomarker that can visualize blood vessel activity, thus optimizing the timing of anticancer therapies including anti-angiogenics.

9 Apr 2018

Using the Microbiome to Predict the Risk of Cirrhosis-Associated Hospitalization

The microbiome is the collection of microorganisms that colonize the human body. Dr. Jasmohan Bajaj discusses the relationship between the microorganisms in the gut and cirrhosis, and how microbiome analysis can be used to predict the risk of cirrhosis-associated hospitalizations.

7 Apr 2018

Scientists develop indices that provide information about prognosis of cancers

Researchers from the School of Medicine in Ribeirão Preto, at the University of São Paulo, in collaboration with international groups, have developed indices that provide information about the prognosis of cancers, aid in the choice of the most appropriate therapy to be used and identify potential targets for the development of new drugs.

6 Apr 2018

Research provides new insights about gender differences in airway disease risk

Human airways already demonstrate gender-based differences in DNA methylation signatures at birth, providing an early hint of which infants may be predisposed to develop respiratory disorders like asthma later in life, a research team reports in a paper published online April 3, 2018, in Scientific Reports.

6 Apr 2018

Johns Hopkins scientist calls for more integration of epigenetics and genetics research

In a review article published April 5 in the New England Journal of Medicine, scientist Andrew Feinberg, M.D., calls for more integration between two fields of DNA-based research: genetics and epigenetics.

6 Apr 2018

McMaster researchers develop transparent test patch to signal food contamination

Is that meat still good? Are you sure? McMaster researchers have developed a test to bring certainty to the delicate but critical question of whether meat and other foods are safe to eat or need to be thrown out.

6 Apr 2018

Scientists identify key genetic events responsible for initiating childhood leukemia

The key genetic events responsible for initiating the early stages of a type of childhood leukemia have been identified by scientists at The Institute of Cancer Research, London. Insights into the ‘founder’ genetic mutation for this type of leukemia, present in all the cancer cells, could be used in the development of new targeted drugs.

6 Apr 2018

DNA News and Research

Further Reading

Short international trips can lead to spread of colistin resistance

Researchers discover how 'junk DNA' plays key role in holding the genome together

Transcription factor Sp7 found to play key role in tooth development

Biomarker panel can guide future therapeutic decisions for glioma patients

Newly discovered predictive biomarkers could help assess level of glioma recurrence risk

New class of drug holds potential to help patients with treatment-resistant cancers

DNA test method can help quickly prevent Legionnaires' outbreak

Finding new drug target for common form of lung cancer

Removal of single mitochondrial protein leads to severe inflammation

New technique makes it possible to trace lineage of each cell

UCLA researchers tweak CRISPR to accelerate genomic editing

Oxidative stress due to lack of tumor suppressor gene promotes cancer progression, study shows

Novel biomarker helps optimize anticancer therapy

Vascular stabilization biomarker helps optimize timing of anticancer therapies

Using the Microbiome to Predict the Risk of Cirrhosis-Associated Hospitalization

Scientists develop indices that provide information about prognosis of cancers

Research provides new insights about gender differences in airway disease risk

Johns Hopkins scientist calls for more integration of epigenetics and genetics research

McMaster researchers develop transparent test patch to signal food contamination

Scientists identify key genetic events responsible for initiating childhood leukemia

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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