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Vanderbilt researchers unravel how bacterial toxin prevents DNA replication

One of the most potent toxins known acts by welding the two strands of the famous double helix together in a unique fashion which foils the standard repair mechanisms cells use to protect their DNA.

2 Aug 2017

Kinase-inactive BRAF mutation triggers lung adenocarcinoma development

The initiating oncogenic event in almost half of human lung adenocarcinomas is still unknown, a fact that complicates the development of selective targeted therapies.

2 Aug 2017

Shaping the future of oncology treatment

Victories Over Cancer is about enabling those affected by cancer to enjoy more of life’s meaning full moments and making cancer more manageable. At Janssen, we're really thinking about the elimination of cancer, and we take a very deliberate approach to that.

2 Aug 2017

Salk scientist Reuben Shaw wins NCI Outstanding Investigator Award

Salk Professor Reuben Shaw has received the National Cancer Institute Outstanding Investigator Award (OIA), which encourages cancer research with breakthrough potential. Shaw, a member of Salk's Molecular and Cell Biology Laboratory and holder of the William R. Brody Chair, will receive $4.2 million in direct funding over the next seven years to further his work.

1 Aug 2017

DNA-sensing mechanism of innate immune system controls cellular senescence

Cells in the body or in cultures eventually stop replicating. This phenomenon is called "senescence" and is triggered by shortening of telomeres, oxidative stress or genetic damage to the cells, either acute or simply due to the cell growing "old".

31 Jul 2017

STRATEC Molecular offers new products to improve liquid biopsy

Liquid biopsy is a new technology for detection and analysis of biomarkers in blood or other body fluids without the need of invasive procedures.

28 Jul 2017

DKFZ scientists reveal how cancer cells suppress immune system to spread and multiply

The degenerated cells cause an inflammatory reaction and influence other blood cells with it so much, that the immune system is suppressed.

28 Jul 2017

Walnuts may contribute to better health by changing makeup of gut bacteria

Research led by Lauri Byerley, PhD, RD, Research Associate Professor of Physiology at LSU Health New Orleans School of Medicine, has found that walnuts in the diet change the makeup of bacteria in the gut, which suggests a new way walnuts may contribute to better health.

28 Jul 2017

Spider threads show great potential for nerve and tissue repair

The golden orb-weaver spider from Tanzania spins such strong webs that Tanzanian fishermen use them for fishing.

28 Jul 2017

DNA-protein structure more diverse and flexible chain than previously thought, study reveals

How can six and half feet of DNA be folded into the tiny nucleus of a cell? Researchers funded by the National Institutes of Health have developed a new imaging method that visualizes a very different DNA structure, featuring small folds of DNA in close proximity.

27 Jul 2017

Case Western Reserve University professor awarded $150,000 for pediatric cancer research

In the United States, more children are lost to cancer than any other disease, and one in 285 children will be diagnosed before they turn 20.

27 Jul 2017

Gut bacterium can stop chemotherapy from causing cancer cell death

Researchers at Michigan Medicine and in China showed that a type of bacterium is associated with the recurrence of colorectal cancer and poor outcomes.

27 Jul 2017

Combining intraoperative imaging with PET scans helps surgeons remove hidden cancer cells

Surgeons were able to identify and remove a greater number of cancerous nodules from lung cancer patients when combining intraoperative molecular imaging (IMI) – through the use of a contrast agent that makes tumor cells glow during surgery – with preoperative positron emission tomography (PET) scans.

27 Jul 2017

UA researchers seek to better understand NHE8 protein’s role in GI disorders, colon cancer

About 1.6 million Americans suffer from inflammatory bowel disease (IBD), which encompasses several painful and complex disorders that include Crohn's disease and ulcerative colitis.

27 Jul 2017

New approach may improve translation of immunological research findings

Mouse models have advanced our understanding of immune function and disease in many ways but they have failed to account for the natural diversity in human immune responses.

27 Jul 2017

Study examines link between RCT efficacy and real-world effectiveness of cancer therapies

Value in Health, the official journal of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR), announced today the publication of new research examining the relationship between the efficacy of randomized controlled trials (RCTs) and real-world effectiveness for oncology treatments.

27 Jul 2017

Stem cell-based method selectively targets cancerous tissue while preventing toxic side effects

A stem cell-based method created by University of California, Irvine scientists can selectively target and kill cancerous tissue while preventing some of the toxic side effects of chemotherapy by treating the disease in a more localized way.

27 Jul 2017

Genetic test that predicts prognosis could benefit early-stage colon cancer patients

Early-stage colon cancer patients could benefit in the future from specific genetic tests that forecast their prognosis and help them make the right decision regarding chemotherapy.

26 Jul 2017

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

A new cooperative research study including Norris Cotton Cancer Center's Lionel Lewis, MB BCh, MD, finds that nivolumab plus ipilimumab therapy demonstrated manageable safety, notable antitumor activity, and durable responses with promising long term overall survival in patients with metastatic renal cell cancer (mRCC).

26 Jul 2017

New compound takes positive step toward creating drug for melanoma

While past attempts to treat melanoma failed to meet expectations, an international team of researchers are hopeful that a compound they tested on both mice and on human cells in a petri dish takes a positive step toward creating a drug that can kill melanoma cancer cells without harming nearby healthy cells.

26 Jul 2017

Tumor News and Research

Vanderbilt researchers unravel how bacterial toxin prevents DNA replication

Kinase-inactive BRAF mutation triggers lung adenocarcinoma development

Shaping the future of oncology treatment

Salk scientist Reuben Shaw wins NCI Outstanding Investigator Award

DNA-sensing mechanism of innate immune system controls cellular senescence

STRATEC Molecular offers new products to improve liquid biopsy

DKFZ scientists reveal how cancer cells suppress immune system to spread and multiply

Walnuts may contribute to better health by changing makeup of gut bacteria

Spider threads show great potential for nerve and tissue repair

DNA-protein structure more diverse and flexible chain than previously thought, study reveals

Case Western Reserve University professor awarded $150,000 for pediatric cancer research

Gut bacterium can stop chemotherapy from causing cancer cell death

Combining intraoperative imaging with PET scans helps surgeons remove hidden cancer cells

UA researchers seek to better understand NHE8 protein’s role in GI disorders, colon cancer

New approach may improve translation of immunological research findings

Study examines link between RCT efficacy and real-world effectiveness of cancer therapies

Stem cell-based method selectively targets cancerous tissue while preventing toxic side effects

Genetic test that predicts prognosis could benefit early-stage colon cancer patients

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

New compound takes positive step toward creating drug for melanoma

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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