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Scientists manage to permeate living cells with small antibodies

Scientists at the Technische Universität Darmstadt, Ludwig Maximilians University Munich and the Leibniz Institute for Molecular Pharmacology have managed to introduce tiny antibodies into living cells. The researchers now report on the synthesis and applications for these nanobodies in "Nature Chemistry".

19 Jul 2017

Latinos left out of clinical trials … and possible cures

Two decades ago, Luis Antonio Cabrera received devastating news: He likely had only three months to live.

19 Jul 2017

Researchers uncover new mechanism that promotes growth of blood vessels in tumors

Cancer cells have an enormous need for oxygen and nutrients. Therefore, growing tumors rely on the simultaneous growth of capillaries, the fine branching blood vessels that form a supply network for them.

18 Jul 2017

Study shows how cells feel their way through the surroundings

Cells push out tiny feelers to probe their physical surroundings, but how much can these tiny sensors really discover? A new study led by Princeton University researchers and colleagues finds that the typical cell's environment is highly varied in the stiffness or flexibility of the surrounding tissue, and that to gain a meaningful amount of information about its surroundings, the cell must move around and change shape.

18 Jul 2017

Researchers discover reason for chemoresistance in small cell lung cancer

Approximately one year after successful treatment with cytotoxic chemotherapy and radiotherapy, patients with advanced Small Cell Lung Cancer (SCLC), which primarily affects heavy smokers, generally relapse with recurrence of tumours that are resistant to further chemotherapy.

18 Jul 2017

New analysis compares emerging algorithms that look for cancer mutations

Sanford Burnham Prebys Medical Discovery Institute has undertaken the first-ever comparative analysis of a newly emerging category of algorithms that mine genetic information in cancer databases by focusing on internal gene structure (subgene resolution algorithms), in contrast to classical approaches that focus on genes treated as single units.

17 Jul 2017

Study: Breast cancer patients receiving neoadjuvant radiation have lower risk of second primary tumor

Moffitt Cancer Center researchers launched a first of its kind study comparing the long-term benefits of radiation therapy in women with breast cancer either before surgery (neoadjuvant) or after surgery (adjuvant).

17 Jul 2017

Scientists develop portable device for detecting circulating tumor cells

Researchers at the URV's Department of Physical and Inorganic Chemistry, led by the ICREA researcher, Ramon Álvarez Puebla, and the professor of Applied Physics, Francesc Díaz, and the Department of Clinical Oncology of the HM Torrelodones University Hospital, have patented a portable device that can detect tumor cells in blood.

17 Jul 2017

Scientists reveal key role of TLK2 gene in placenta development, embryo viability in mice

The placenta, a transient organ that links the developing embryo to its mother, is responsible for nutrient, waste and gas exchange between the fetus and the mother.

17 Jul 2017

CNIC research holds potential to improve current cancer immunotherapy strategies

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have investigated how different subtypes of essential immune-response cells called CD8+ T lymphocytes cooperate to mount a stronger anti-tumor response.

17 Jul 2017

Lymph node removal may not be needed for all melanoma patients, study finds

Many patients with melanoma need a sentinel-lymph-node biopsy to determine if cancer cells have spread there, but a positive finding doesn't mean all the lymph nodes in the area must be removed, according to new international study.

17 Jul 2017

Southampton researchers find new approach to reverse treatment resistance in lymphoma patients

Researchers from the University of Southampton have identified why some people may become resistant to monoclonal antibodies, a common type of immunotherapy used in lymphoma treatment.

17 Jul 2017

Bacterium S. gallolyticus appears to actively promote development of colorectal cancer

Colorectal cancer is fairly treatable when caught early with regular screenings, but it is still the second-leading cause of cancer-related deaths in American men and the third-leading cause in women.

17 Jul 2017

MGH researchers identify novel mechanism behind resistance to angiogenesis inhibitors

A Massachusetts General Hospital research team has identified a novel mechanism behind resistance to angiogenesis inhibitors - drugs that fight cancer by suppressing the formation of new blood vessels.

14 Jul 2017

BWH researchers use specific microRNA to identify, alter makeup of glioblastoma subtypes

Glioblastoma multiforme (GBM), an extremely aggressive brain cancer, is a very complex disease. It is characterized by a fast-growing tumor in the brain composed of many subpopulations of cells, including glioblastoma stem cells, which play a crucial role in glioblastoma initiation, expansion and therapy-resistance.

14 Jul 2017

FDA panel recommends new breakthrough gene therapy for B-cell acute lymphoblastic leukemia (ALL)

A Food and Drug Administration (FDA) panel created history by recommending a gene therapy for patients with cancer. In this therapy the patient’s own genes would be modified to fight the cancer cells. The patient’s cells which are thus altered to treat the cancer would thus be termed as “living drugs” as they act as soldiers to treat the cancer. These cells boost up the immune system and help the body fight the cancer.

14 Jul 2017

Daily tomato consumption may cut skin cancer by half, mouse study shows

Daily tomato consumption appeared to cut the development of skin cancer tumors by half in a mouse study at The Ohio State University.

13 Jul 2017

Beaumont Health's new Proton Therapy Center starts treating cancer patients

Bill Baker, an 86-year-old Mid-Michigan man with brain cancer, is the first patient to receive treatment at Beaumont Health's new Proton Therapy Center at Beaumont Hospital in Royal Oak, Michigan.

13 Jul 2017

Cancer metastases may originate from primary tumor without involving lymph system

Research by several leading scientists including Rakesh Jain, PhD, Director of the Edwin L. Steele Laboratory for Tumor Biology at the Massachusetts General Hospital and supported in part by the National Foundation for Cancer Research, has provided the first evidence that the century-old model for cancer metastasis - where cancer spreads from primary tumor to nearby lymph nodes, and then to other organs - may not apply in all cases.

13 Jul 2017

ASTRO releases updated insurance coverage recommendations for proton beam therapy to treat cancer

The American Society for Radiation Oncology has issued an update to its recommendations for medical insurance coverage regarding the use of proton beam therapy to treat cancer.

13 Jul 2017

Tumor News and Research

Scientists manage to permeate living cells with small antibodies

Latinos left out of clinical trials … and possible cures

Researchers uncover new mechanism that promotes growth of blood vessels in tumors

Study shows how cells feel their way through the surroundings

Researchers discover reason for chemoresistance in small cell lung cancer

New analysis compares emerging algorithms that look for cancer mutations

Study: Breast cancer patients receiving neoadjuvant radiation have lower risk of second primary tumor

Scientists develop portable device for detecting circulating tumor cells

Scientists reveal key role of TLK2 gene in placenta development, embryo viability in mice

CNIC research holds potential to improve current cancer immunotherapy strategies

Lymph node removal may not be needed for all melanoma patients, study finds

Southampton researchers find new approach to reverse treatment resistance in lymphoma patients

Bacterium S. gallolyticus appears to actively promote development of colorectal cancer

MGH researchers identify novel mechanism behind resistance to angiogenesis inhibitors

BWH researchers use specific microRNA to identify, alter makeup of glioblastoma subtypes

FDA panel recommends new breakthrough gene therapy for B-cell acute lymphoblastic leukemia (ALL)

Daily tomato consumption may cut skin cancer by half, mouse study shows

Beaumont Health's new Proton Therapy Center starts treating cancer patients

Cancer metastases may originate from primary tumor without involving lymph system

ASTRO releases updated insurance coverage recommendations for proton beam therapy to treat cancer

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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