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Immune response in SARS-CoV-1 survivors after COVID-19 vaccination

Researchers evaluate SARS-CoV-2 vaccine-induced immune responses in SARS survivors.

23 Oct 2022

FebriDX point-of-care immunoassay can rapidly determine if an infection is bacterial or viral

Researchers explore whether FebriDx could differentiate between bacteria- and virus-induced immune responses during acute respiratory infection.

23 Oct 2022

Biochemical and structural evidence demonstrates Omicron mutations are better adapted to mouse ACE2 than to human ACE2

Researchers demonstrated the structural basis of how the receptor-binding domain nested Omicron mutations have adapted to mouse angiotensin-converting enzyme 2 rather than human ACE2.

22 Oct 2022

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Researchers at Boston University made a chimeric recombinant SARS-CoV-2 encoding the spike glycoprotein gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate.

22 Oct 2022

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Researchers performed retrospective detection of the monkeypox virus in the testes of nonhuman primates.

22 Oct 2022

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

In a recent study published in the journal Nature Cell Biology, researchers demonstrated the susceptibility of salivary glands to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in vitro using an organoid culture model.

20 Oct 2022

Are pediatric COVID-19 samples less infectious?

Researchers determine whether children are less hospitable to SARS-CoV-2 and, as a result, pose a lower risk of a viral spread than adults.

20 Oct 2022

Breakthrough infection risk and immune responses to vaccines associated with human leukocyte antigen alleles

Researchers from the U.K. used data from clinical trials of the Oxford-AstraZeneca COVID-19 vaccine ChAdOx1 nCoV-19 to understand the genetic factors contributing to the individual variations in the antibody responses to the vaccine.

20 Oct 2022

Why do some people attract mosquitoes more than others?

Mosquitoes (e.g., Aedes aegypti) are common vectors for many viruses that infect the human population, such as dengue, Zika, and yellow fever.

19 Oct 2022

SARS-CoV-2 transmission from infected owner to pet rats

SARS-CoV-2 Omicron transmission from a symptomatically infected individual to two domestic rats.

19 Oct 2022

Differential effects of SARS-CoV-2 variants on children and adolescents

A recent Emerging Infectious Diseases journal study evaluated whether specific SARS-CoV-2 variants were linked with different clinical manifestations in children and adolescents.

19 Oct 2022

Rapid and robust pipeline for developing mRNA vaccines for future SARS-CoV-2 variants

A recent study under review at the journal Scientific Reports and currently available on the Research Square* preprint server reported the development of a robust pipeline for fabricating an mRNA vaccine portfolio to combat current and future coronavirus outbreaks, other infectious diseases, and cancer.

19 Oct 2022

Researchers assess wastewater sampling for SARS-CoV-2 surveillance

Researchers assessed the feasibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surveillance using wastewater sampling.

18 Oct 2022

On-site ultrasensitive monkeypox viral testing using CRISPR/Cas12a

In a new study posted to the medRxiv* preprint server, researchers in China developed an MPXV assay combining clustered regularly interspaced short palindromic repeats and CRISPR-associated protein (CRISPR/Cas) and recombinase-aided amplification (RAA) for the first time.

18 Oct 2022

Recent innovations in infectious disease diagnostics

A recent Clinical Biochemistry editorial reports the latest innovations in the field of infectious disease diagnostics.

17 Oct 2022

Investigating plasma signatures of platelet-derived proteins in acute pulmonary embolism

In a new study, researchers determined plasma signatures of proteins related to or derived from platelets in acute isolated pulmonary embolism (iPE) and deep vein thrombosis-associated PE (DVT-PE), compared to isolated DVT (iDVT).

17 Oct 2022

Owner SARS-CoV-2 RNA load shown to be associated with infection in pet dogs

A new study assessed the potential association of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) load in owners with SARS-CoV-2 infection in their dogs.

17 Oct 2022

Immunity conferred by influenza vaccinations found to be independent of vaccination timing

Researchers evaluated the impact of the timing of influenza (flu) vaccine administration on vaccine-induced immunity against infection.

17 Oct 2022

Increased TMPRSS2 expression in tongue tissue of females and alcohol drinkers identified as a potential risk factor for SARS-CoV-2 infection

Researchers explored the association between the expressions of the ACE-2 receptor and TMPRSS2 in the tongue tissue and dysgeusia during SARS-CoV-2 infections.

17 Oct 2022

Inhalation therapeutics against COVID-19

A recent study published in the Pulmonary Pharmacology & Therapeutics journal described different inhalation therapeutic agents for treating respiratory viral infections like coronavirus disease 2019 (COVID-19).

17 Oct 2022

Assay News and Research

Immune response in SARS-CoV-1 survivors after COVID-19 vaccination

FebriDX point-of-care immunoassay can rapidly determine if an infection is bacterial or viral

Biochemical and structural evidence demonstrates Omicron mutations are better adapted to mouse ACE2 than to human ACE2

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

Are pediatric COVID-19 samples less infectious?

Breakthrough infection risk and immune responses to vaccines associated with human leukocyte antigen alleles

Why do some people attract mosquitoes more than others?

SARS-CoV-2 transmission from infected owner to pet rats

Differential effects of SARS-CoV-2 variants on children and adolescents

Rapid and robust pipeline for developing mRNA vaccines for future SARS-CoV-2 variants

Researchers assess wastewater sampling for SARS-CoV-2 surveillance

On-site ultrasensitive monkeypox viral testing using CRISPR/Cas12a

Recent innovations in infectious disease diagnostics

Investigating plasma signatures of platelet-derived proteins in acute pulmonary embolism

Owner SARS-CoV-2 RNA load shown to be associated with infection in pet dogs

Immunity conferred by influenza vaccinations found to be independent of vaccination timing

Increased TMPRSS2 expression in tongue tissue of females and alcohol drinkers identified as a potential risk factor for SARS-CoV-2 infection

Inhalation therapeutics against COVID-19

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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