Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Researchers discover novel class of safer analgesics

Researchers at LSU Health New Orleans Neuroscience Center of Excellence and colleagues have discovered a new class of pipeline drugs to relieve pain and reduce fever without the danger of addiction or damage to the liver or kidneys.

6 Jul 2020

Study: Oats and rye brans reduce weight gain, hepatic inflammation

In a newly published experimental study, the consumption of dietary fibre from oat and rye brans supported the growth of beneficial gut microbiota, which in turn ameliorated cholesterol metabolism, enhanced gut barrier function and reduced hepatic inflammation.

2 Jul 2020

Novel microbiome-based diagnostic tool can identify liver fibrosis, cirrhosis

Chronic liver disease represents a major global public health problem affecting an estimated 844 million people, according to the World Health Organization. It is among the top causes of mortality in Australia, the UK and the United States.

2 Jul 2020

Repeated sampling of FIB-4 score can increase the prediction of future liver cirrhosis

Repeated measurements of the biomarker FIB-4 in the blood every few years can predict the risk of developing severe liver disease, according to a new study from Karolinska Institutet in Sweden published in the Journal of Hepatology.

1 Jul 2020

Stool microbial and metabolite signatures predict cirrhosis

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide, affecting an estimated one-quarter of the global population. It is a progressive condition that, in worst cases, can lead to cirrhosis, liver cancer, liver failure and death.

30 Jun 2020

The gut shields the liver from fructose-induced lipogenesis

After one consumes food or a beverage containing fructose, the gastrointestinal system, or gut, helps to shield the liver from damage by breaking down the sugar before it reaches the liver, according to a new multi-center study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

29 Jun 2020

Review highlights why and to what extent a large hip protects from type 2 diabetes and CVD

In a Lancet Diabetes & Endocrinology review article Norbert Stefan from the German Center for Diabetes Research, the University Hospital of Tübingen and the Boston Children's Hospital, highlights why and to what extent a large hip circumference, an estimate of increased fat mass in the lower part of the body, protects from type 2 diabetes and cardiovascular diseases.

18 Jun 2020

Study investigates effectiveness of liver perfusion to improve the function of donor livers

A major study investigating the effectiveness of liver perfusion as a technique to improve the function of donor livers that would have otherwise been rejected has shown that up to 7 in every 10 could be used after just 4-6 hours of the assessment.

17 Jun 2020

Even brief exposure to certain chemicals can prematurely age the liver epigenome

The epigenome is sometimes referred to as the "software" or "operating system" of the genome. It comprises small chemical modifications to DNA and the proteins that make up our chromosomes, and controls the activity of all the genes within the genome.

17 Jun 2020

Novel antisense drug shows promise to improve health of people with NAFLD

Using a first-of-its-class drug in a clinical trial, an international research effort headed by a scientist at University of California San Diego School of Medicine reports that inhibition of a key enzyme safely and effectively improved the health of persons with non-alcoholic fatty liver disease, a chronic metabolic disorder that affects hundreds of millions of people worldwide.

16 Jun 2020

Creating the first 3D neural map of a heart

News-Medical spoke to Dr. Vadigepalli and Dr. Schwaber about their groundbreaking research in which they managed to map the neurons in the heart.

15 Jun 2020

Researchers explore amino acids for a new diet approach

A new diet approach that restricts essential amino acids was explored in new research by a team of international scientists from Australia, Denmark, and Germany.

11 Jun 2020

Scientists develop new test to help identify people at risk for developing liver cancer

Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the patient's previous exposure to certain viruses.

11 Jun 2020

BAM15 could be an effective drug for treating obesity and related diseases

A new study offers the first evidence that a protein named BAM15 acts as an energy uncoupler and could be an effective drug for treating obesity and related diseases.

10 Jun 2020

Study provides new evidence that liver dysfunction may lead to heart disease

A new study that looks closely at the cardiac health of flies provides new evidence that liver dysfunction may lead to deterioration of the heart.

10 Jun 2020

Research team provides new insights on the communication between liver and brain

A research team in Vienna is investigating how calorie intake, liver activity and fat storage interact and what role the central nervous system plays in this.

10 Jun 2020

Research demonstrates novel pathway regulating the underlying mechanism of NASH

CN Bio, a leading cell culture company that has developed single and multi-organ microphysiological systems that improve the accuracy and efficiency of drug discovery, today announced the publication of co-authored research led by researchers at the University of Cambridge in Nature Metabolism, identifying a novel pathway that regulates the underlying mechanism of Non-Alcoholic Steatohepatitis, potentially a new therapeutic target.

10 Jun 2020

Liver Disease News and Research

Further Reading

Researchers discover novel class of safer analgesics

Study: Oats and rye brans reduce weight gain, hepatic inflammation

Novel microbiome-based diagnostic tool can identify liver fibrosis, cirrhosis

Repeated sampling of FIB-4 score can increase the prediction of future liver cirrhosis

Stool microbial and metabolite signatures predict cirrhosis

The gut shields the liver from fructose-induced lipogenesis

Review highlights why and to what extent a large hip protects from type 2 diabetes and CVD

Study investigates effectiveness of liver perfusion to improve the function of donor livers

Even brief exposure to certain chemicals can prematurely age the liver epigenome

Novel antisense drug shows promise to improve health of people with NAFLD

Creating the first 3D neural map of a heart

Researchers explore amino acids for a new diet approach

Scientists develop new test to help identify people at risk for developing liver cancer

BAM15 could be an effective drug for treating obesity and related diseases

Study provides new evidence that liver dysfunction may lead to heart disease

Research team provides new insights on the communication between liver and brain

Research demonstrates novel pathway regulating the underlying mechanism of NASH

Fecal transplants could be used as treatment for non-alcoholic fatty liver disease

Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

MUSC receives $16.5 million NIH funding to open two new digestive disease research centers

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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