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New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

The first drug using spherical nucleic acids to be systemically given to humans has been developed by Northwestern University scientists and approved by the Food and Drug Administration as an investigational new drug for an early-stage clinical trial in the deadly brain cancer glioblastoma multiforme.

12 May 2017

Scientists discover free C3d protein that mitigates tumor-induced immunosuppression

In the body, anti-cancer immunity is immobilized by stealth cancer forces. But a natural de-immobilizer has been identified-;and it has a vendetta.

12 May 2017

Immunoreceptor promotes tumor growth in mouse models of liver cancer driven by inflammation

Boosting a part of the immune system known to have anti-tumor properties may actually help tumors grow in cancers linked to chronic inflammation.

12 May 2017

TUM scientists develop new pH sensor that provides insights into tumor metabolism

Tumors, inflammation and circulatory disorders locally disturb the body's acid-base balance. These changes in pH value could be used for example to verify the success of cancer treatments.

12 May 2017

Phase 1 trial shows safety and tolerability of oncolytic HSV-1 for children, young adults with cancer

HSV1716 – an oncolytic herpes simplex virus-1 – has been studied in adults via injection into the brain and superficial tumors.

11 May 2017

Study reveals how proline metabolism supports breast cancer metastasis

A multinational group of scientists, led by professor Sarah-Maria Fendt, have discovered that breast cancer cells that have invaded other organs rely on a different nutrient metabolism to produce energy than normal cells and non-metastasizing cancer cells.

11 May 2017

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

The low oxygen concentrations that prevail in many tumors enhance their propensity to metastasize to other tissues. Researchers at Ludwig-Maximilians-Universitaet in Munich led by Professor Heiko Hermeking have now uncovered the molecular mechanism that links the two phenomena.

11 May 2017

Scientists produce world's first CT images of biological tissue using protons

An international team of scientists has produced the world's first computerized tomography images of biological tissue using protons - a momentous step towards improving the quality and feasibility of Proton Therapy for cancer sufferers around the world.

11 May 2017

Deep-learning network provides accurate detection and delineation of breast cancers on biopsy slides

A deep-learning computer network developed through research led by Case Western Reserve University was 100 percent accurate in determining whether invasive forms of breast cancer were present in whole biopsy slides.

11 May 2017

Primary care prescription data could help guide GP referrals, improve early diagnosis of cancer

Cancer Research UK-funded scientists are to examine whether identifying patterns in medication given to patients before they develop cancer could improve early diagnosis.

11 May 2017

UT Health scientists discover epigenetic changes that contribute to AML

UT Health San Antonio researchers discovered epigenetic changes that contribute to one-fifth of cases of acute myeloid leukemia (AML), an aggressive cancer that arises out of the blood-forming cells in bone marrow.

10 May 2017

CNIO researchers optimize new system capable of generating cellular model of Ewing sarcoma

A team from the Spanish National Cancer Research Centre (CNIO) has optimized a system capable of generating a cellular model of Ewing sarcoma.

10 May 2017

UC researchers find stem cell vaccine to enhance immune responses against tumors in animal models

Researchers at the University of Cincinnati have found that a cancer stem cell vaccine, engineered to express a pro-inflammatory protein called interleukin-15 (IL-15) and its receptor (IL-15Ralpha), caused T cell production in animal models and enhanced immune responses against tumors.

10 May 2017

Research illuminates how primary colorectal tumors contribute to premetastatic 'niche' formation

Primary colorectal tumors secrete VEGF-A, inducing CXCL1 and CXCR2-positive myeloid-derived suppressor cell (MDSC) recruitment at distant sites and establishing niches for future metastases, report Medical University of South Carolina investigators in an article published online ahead of print on April 28, 2017 by Cancer Research.

10 May 2017

New trial aims to prolong remission for pediatric leukemia patients treated with T-cell immunotherapy

After phase 1 results of Seattle Children's Pediatric Leukemia Adoptive Therapy trial have shown T-cell immunotherapy to be effective in getting 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia into complete initial remission, researchers have now opened a first-in-human clinical trial aimed at reducing the rate of relapse after the therapy, which is about 50 percent.

9 May 2017

Tumor News and Research

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

Scientists discover free C3d protein that mitigates tumor-induced immunosuppression

Immunoreceptor promotes tumor growth in mouse models of liver cancer driven by inflammation

TUM scientists develop new pH sensor that provides insights into tumor metabolism

Phase 1 trial shows safety and tolerability of oncolytic HSV-1 for children, young adults with cancer

Study reveals how proline metabolism supports breast cancer metastasis

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

Scientists produce world's first CT images of biological tissue using protons

Deep-learning network provides accurate detection and delineation of breast cancers on biopsy slides

Primary care prescription data could help guide GP referrals, improve early diagnosis of cancer

UT Health scientists discover epigenetic changes that contribute to AML

CNIO researchers optimize new system capable of generating cellular model of Ewing sarcoma

UC researchers find stem cell vaccine to enhance immune responses against tumors in animal models

Research illuminates how primary colorectal tumors contribute to premetastatic 'niche' formation

New trial aims to prolong remission for pediatric leukemia patients treated with T-cell immunotherapy

Studies pave way for genome-targeted treatments in pancreatic cancer

Stereotactic partial breast radiation decreases treatment time from six weeks to just days

Elekta Unity (MR/RT) featured in 20 abstracts at ESTRO

Elekta Unity introduced transformative magnetic resonance radiation therapy at ESTRO

UT Southwestern researchers uncover mechanism linked to balding and hair graying

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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