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Collaborative research yields a wiring map on how TB responds to changes in environment

Despite decades of research on the bacterium that causes tuberculosis (TB), scientists have not had a comprehensive understanding of how the bacterium is wired to adapt to changing conditions in the host.

5 Jul 2013

Consanguineous marriages and older mothers increase risk of birth anomalies in children

Marriage between first cousins can more than double the risk of giving birth to a baby with a congenital anomaly (eg, heart and lung defects, Down syndrome), although the absolute risk is low, according to a multiethnic study of more than 11300 babies from the city of Bradford in the UK, published in The Lancet.

5 Jul 2013

Genetic cause identified for diffuse non-epidermolytic palmoplantar keratoderma

Scientists have identified the genetic cause of a rare skin condition that causes the hands and feet to turn white and spongy when exposed to water.

4 Jul 2013

Saltwater-treatment for cystic fibrosis: an interview with Matthew Allen, Program Director at Cambridge Consultants

A group of Australian researchers, back in 2006, noted that there was a link between the severity of cystic fibrosis between sufferers who surfed, and sufferers who did not surf – and obviously Australia is a good place to spot that.

4 Jul 2013

Study shows possible biological cause of narcolepsy

In 2000, researchers at the UCLA Center for Sleep Research published findings showing that people suffering from narcolepsy, a disorder characterized by uncontrollable periods of deep sleep, had 90 percent fewer neurons containing the neuropeptide hypocretin in their brains than healthy people.

4 Jul 2013

Research highlights main factors associated with increased risk of babies born with birth defect

New research, published today in The Lancet, highlights important information for health professionals and parents about the factors which may increase the likelihood of a baby being born with a birth defect.

4 Jul 2013

Study shows miR-22 plays a key role in breast and blood cancers

A mere 25 years ago, noncoding RNAs were considered nothing more than "background noise" in the overall genomic landscape. Now, two new studies reveal that one of these tiny noncoding molecules - microRNA-22 - plays an outsized role in two types of cancer.

4 Jul 2013

Study shows activated blood platelets enable cancer cells to penetrate blood vessels

Malignant tumours often spread to remote areas of the body. In the majority of cases, metastases formation develops via the blood vascular system. The blood platelets thereby provide invaluable help to the tumour cells in penetrating new organs.

4 Jul 2013

Telemonitoring with pharmacist management improves and maintains BP control

An intervention that consisted of home blood pressure (BP) telemonitoring with pharmacist management resulted in improvements in BP control and decreases in BP during 12 months, compared with usual care, and improvement in BP that was maintained for 6 months following the intervention, according to a study in the July 3 issue of JAMA.

3 Jul 2013

NIDA grants $3.3M to design vaccine conferring immunity to nicotine

A chemical component present in the nightshade family of plants is one of the world's most tenaciously addictive substances. It is the nicotine contained in tobacco and found in high concentrations in cigarettes. Smoking remains a global scourge; in the U.S. it is the leading source of preventable death.

3 Jul 2013

Researchers find NRF2 signaling plays a role in growth of tumor cells by altering metabolic pathways

Cancer cells have alteration in metabolic pathways as a result of oncogenes that promote tumor growth. NRF2 (nuclear factor erythroid-derived 2-related factor 2) works as a "master gene" that turns on stress response by increasing numerous antioxidants and pollutant-detoxifying genes to protect the lungs from variety of air pollutants such as diesel exhaust and cigarette smoke.

3 Jul 2013

Curcumin may provide lasting protection against lung damage in premature infants

Turmeric, a key ingredient in spicy curry dishes, has long been known to have medicinal values. Now new research finds a substance in turmeric, curcumin, may provide lasting protection against potentially deadly lung damage in premature infants.

3 Jul 2013

First Edition: July 2, 2013

Today's headlines include various reports about changes afoot in the insurance marketplace.

2 Jul 2013

UCLA researchers introduce gene therapy technique to treat sickle cell disease

Researchers at UCLA's Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research have successfully established the foundation for using hematopoietic (blood-producing) stem cells from the bone marrow of patients with sickle cell disease to treat the disease.

2 Jul 2013

Research roundup: 'Welcome-mat' effect of Medicaid expansion; Setting up shops; California's transition to Medicaid managed care

The number of people eligible for Medicaid who remain uninsured varies from state to state, according to the authors. But the federal health law is likely to increase the rate of enrollment for this group. The potential impact of this increase in Medicaid enrollment, also known as the 'welcome-mat' effect, is unclear.

2 Jul 2013

Fondation Leducq grants $6M to cardiovascular scientists to help advance cardiac regeneration therapeutics

The Fondation Leducq in Paris, France, dedicated to improving human health through international efforts to combat cardiovascular disease, awarded a $6 million grant award to a new global research network of cardiovascular scientists which includes three researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai.

2 Jul 2013

Lungs News and Research

Collaborative research yields a wiring map on how TB responds to changes in environment

Consanguineous marriages and older mothers increase risk of birth anomalies in children

Genetic cause identified for diffuse non-epidermolytic palmoplantar keratoderma

Saltwater-treatment for cystic fibrosis: an interview with Matthew Allen, Program Director at Cambridge Consultants

Study shows possible biological cause of narcolepsy

Research highlights main factors associated with increased risk of babies born with birth defect

Study shows miR-22 plays a key role in breast and blood cancers

Study shows activated blood platelets enable cancer cells to penetrate blood vessels

Telemonitoring with pharmacist management improves and maintains BP control

NIDA grants $3.3M to design vaccine conferring immunity to nicotine

Researchers find NRF2 signaling plays a role in growth of tumor cells by altering metabolic pathways

Curcumin may provide lasting protection against lung damage in premature infants

First Edition: July 2, 2013

UCLA researchers introduce gene therapy technique to treat sickle cell disease

Research roundup: 'Welcome-mat' effect of Medicaid expansion; Setting up shops; California's transition to Medicaid managed care

Fondation Leducq grants $6M to cardiovascular scientists to help advance cardiac regeneration therapeutics

Scientists track down origins of fibrosis-promoting cells that scar and destroy organs

ALK immunocytochemistry accurately detects NSCLC on cytological specimens

Researchers use two new methods to detect levels of ALK protein expression in NSCLC

SBRT treatment safe and effective for stage I NSCLC, study finds

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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