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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

TUM scientists discover emergency shut-off switch for T cell Non-Hodgkin's lymphoma

Safety switches that automatically stop the device for example before it overheats are built into many electrical appliances. Cells are also equipped with such "emergency stop" functions. They make sure that a defective cell doesn't become a tumor cell.

6 Dec 2017

Immune-boosting drug combination may hold promise for treating ovarian cancer

Johns Hopkins Kimmel Cancer Center researchers demonstrated that mice with ovarian cancer that received drugs to reactivate dormant genes along with other drugs that activate the immune system had a greater reduction of tumor burden and significantly longer survival than those that received any of the drugs alone.

5 Dec 2017

Conventional sunscreens do not block skin damage caused by visible light

There is something wrong with people's exposure to sunlight. Despite rising worldwide consumption of sunscreens, the number of cases of skin cancer continues to grow. One of the reasons may be the action of visible light, which is also harmful to skin and is not blocked by conventional sunscreens.

5 Dec 2017

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

The investigational Zika purified inactivated virus (ZPIV) vaccine was well-tolerated and induced an immune response in participants, according to initial results from three Phase 1 clinical trials.

5 Dec 2017

Biological Applications of AFM

An interview with Samuel Lesko, European Applications Manager, Bruker Nano Surfaces conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 5 Dec 2017

DNA sequencing could identify genetic cause of kidney disease

DNA sequencing could soon become part of the routine diagnostic workup for patients with chronic kidney disease, suggests a new study from Columbia University Medical Center.

5 Dec 2017

New biomarker test can accurately predict which chemical compounds induce DNA damage

A new biomarker test developed by researchers at Georgetown Lombardi Comprehensive Cancer Center and their colleagues can help predict, with up to 90 percent certainty, which chemical compounds can cause DNA damage that could lead to cancer.

5 Dec 2017

Research shows how cells rebuild nucleus, organize genome after division

University of Bristol research has revealed how cells rebuild their nucleus and organise their genome when they divide - a discovery which could have major implications for understanding cancer and degeneration.

4 Dec 2017

Study reveals gene linked to metastatic melanoma

A study by Craig J. Ceol, PhD, assistant professor of molecular medicine at the University of Massachusetts Medical School, has revealed a protein active during early embryo development called GDF6 plays a primary role in metastatic melanoma.

4 Dec 2017

Genetic susceptibility to BD can increase suicide risk among people exposed to traumatic stress

Genetic susceptibility to bipolar disorder can increase the risk for suicide attempt, but only among those who also have experienced traumatic stress, reports a study published in the December 2017 issue of the Journal of the American Academy of Child and Adolescent Psychiatry.

4 Dec 2017

New CSHL method pinpoints which prostate tumors pose fatal threat before surgery

The facts about prostate cancer can be confusing. It's the third most common cancer type among Americans - 161,000 men will be diagnosed this year, the National Cancer Institute estimates. Yet according to the NCI, 98.6% will be alive in 5 years.

1 Dec 2017

Australian researchers develop new risk scoring system to predict childhood leukemia relapse

Australian researchers have developed a new risk scoring system for children with leukemia based on missing DNA fragments or 'microdeletions'.

1 Dec 2017

Oral bacteria that lead to periodontal disease linked to higher risk of esophageal cancer

An analysis of bacteria present in the mouth showed that some types of bacteria that lead to periodontal disease were associated with higher risk of esophageal cancer.

1 Dec 2017

Scientists identifies new genetic changes that increase risk of developing Hodgkin lymphoma

People who inherit genetic changes which alter the function of their immune system are at increased risk of developing Hodgkin lymphoma, a major new study reports.

1 Dec 2017

Genetics may affect how the body responds to a particular diet

We can add one more thing to the list of traits affected by genetics: how our bodies respond to a particular diet.

1 Dec 2017

Papillomaviruses linked to UV light promote development of non-melanoma skin cancer

UV radiation has been known for a long time to be a risk factor for the development of skin cancer. Simultaneous infection with human papillomaviruses (HPV) has also been suspected to promote skin cancer, particularly in organ transplant recipients.

30 Nov 2017

New software could make real-time DNA-authentication a reality

In the science-fiction movie Gattaca, visitors only clear security if a blood test and readout of their genetic profile matches the sample on file. Now, cheap DNA sequencers and custom software could make real-time DNA-authentication a reality.

30 Nov 2017

Researchers create first semi-synthetic organism that can store and use unnatural genetic information

Researchers from The Scripps Research Institute (TSRI) have designed a bacterium that incorporates two unnatural bases, called X and Y, into genes, in addition to the four natural DNA bases − G, C, A and T − that usually code for proteins.

30 Nov 2017

Researchers discover rare genetic variant that offers protection against Alzheimer's disease

Research published Wednesday in Genome Medicine details a novel and promising approach in the effort to treat Alzheimer's disease.

30 Nov 2017

Study focuses on improving pharmacokinetic properties of therapeutic aptamers

Designing new therapeutic DNA aptamers with diverse side chains can improve their ability to interact with targets, and a new study describes characteristics of these side chains that may determine how long the aptamers remain in the bloodstream.

30 Nov 2017

DNA News and Research

Further Reading

TUM scientists discover emergency shut-off switch for T cell Non-Hodgkin's lymphoma

Immune-boosting drug combination may hold promise for treating ovarian cancer

Conventional sunscreens do not block skin damage caused by visible light

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

Biological Applications of AFM

DNA sequencing could identify genetic cause of kidney disease

New biomarker test can accurately predict which chemical compounds induce DNA damage

Research shows how cells rebuild nucleus, organize genome after division

Study reveals gene linked to metastatic melanoma

Genetic susceptibility to BD can increase suicide risk among people exposed to traumatic stress

New CSHL method pinpoints which prostate tumors pose fatal threat before surgery

Australian researchers develop new risk scoring system to predict childhood leukemia relapse

Oral bacteria that lead to periodontal disease linked to higher risk of esophageal cancer

Scientists identifies new genetic changes that increase risk of developing Hodgkin lymphoma

Genetics may affect how the body responds to a particular diet

Papillomaviruses linked to UV light promote development of non-melanoma skin cancer

New software could make real-time DNA-authentication a reality

Researchers create first semi-synthetic organism that can store and use unnatural genetic information

Researchers discover rare genetic variant that offers protection against Alzheimer's disease

Study focuses on improving pharmacokinetic properties of therapeutic aptamers

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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