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Comprehensive atlas of protein kinases could help scientists decipher many cellular signaling pathways

One of the most important classes of human enzymes are protein kinases -; signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism.

12 Jan 2023

COVID-19 booster doses could significantly reduce the incidence of SARS-CoV-2 infection among young adults

A recent study published in the journal PLOS Medicine examined the effectiveness of booster doses of coronavirus disease 2019 (COVID-19) vaccines in protecting vaccinated young adults against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections during the dominant period of the Omicron BA.1 variant.

12 Jan 2023

Brain structures could predict an person's predisposition to accidental awareness under anesthesia

Brain structures which could predict an individual's predisposition to accidental awareness under anesthetic have been identified for the first time by neuroscientists in Trinity College Dublin.

12 Jan 2023

Caterpillars could be used as an alternative to mammalian models to study gut inflammation

Rats and mice have been the backbone of biomedical research for decades -; including research to understand cancer and pioneer new treatments.

12 Jan 2023

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

Immune checkpoint inhibitors are important medications that boost the immune system's response against various cancers, but some patients' cancer cells are unaffected by the drugs or develop resistance during treatment.

12 Jan 2023

Reshaping the gut microbiome could be a possible way to prevent or treat neurodegeneration

A growing pile of evidence indicates that the tens of trillions of microbes that normally live in our intestines -; the so-called gut microbiome -; have far-reaching effects on how our bodies function.

12 Jan 2023

New insights into deadly fungal invasion in people with compromised immune systems

Fungi such as Aspergillus are so common in our surroundings that we breathe in hundreds to thousands of spores every day.

12 Jan 2023

Machine learning-based behavioral intervention can improve end-of-life cancer care

Electronic nudges delivered to health care clinicians based on a machine learning algorithm that predicts mortality risk quadrupled rates of conversations with patients about their end-of-life care preferences, according to the long-term results of a randomized clinical trial published by Penn Medicine investigators in JAMA Oncology today.

12 Jan 2023

Social isolation is a risk factor for dementia in community-dwelling older adults, studies show

In two studies using nationally representative data from the National Health and Aging Trends Study gathered on thousands of Americans, researchers from the Johns Hopkins University School of Medicine and Bloomberg School of Public Health have significantly added to evidence that social isolation is a substantial risk factor for dementia in community-dwelling (noninstitutionalized) older adults, and identified technology as an effective way to intervene.

12 Jan 2023

Study reveals how new cells join existing tissues by reading mechanical information

Integration is not only a problem of social significance among humans, but also an issue for the cells that form us as humans.

12 Jan 2023

ADDF-Harrington partnership accelerates the translation of innovative Alzheimer's research into therapies

The Alzheimer's Drug Discovery Foundation and Harrington Discovery Institute at University Hospitals in Cleveland have granted an ADDF-Harrington Scholar Award to Christiane Wrann, PhD, DVM, Associate Professor in Medicine at the Cardiovascular Research Center and the McCance Center for Brain Health at Massachusetts General Hospital and the Harvard Medical School in Boston.

12 Jan 2023

Breast milk of people vaccinated against COVID-19 provides protection to infants, study reveals

A new study from the University of Florida provides more evidence that the breast milk of people vaccinated against COVID-19 provides protection to infants too young to receive the vaccine.

12 Jan 2023

How might healthcare transform in the next 50 years?

A new study published in Futures highlighted key factors likely to influence the evolution of medicine over the next 50 years. These factors included wellness technologies, data-driven personalization, and climate change.

12 Jan 2023

Immunotherapy prior to surgery strikingly effective for patients with colorectal cancer

New research in the January 2023 issue of JNCCN-;Journal of the National Comprehensive Cancer Network finds that immunotherapy from immune checkpoint (PD-1) inhibitors prior to surgery was strikingly effective for patients with localized mismatch repair-deficient or microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC).

12 Jan 2023

Screening patients for hidden reservoirs of bacteria could supplement infection-control efforts in hospitals

Hospitals have strict hygiene and sanitation protocols to protect patients from bacteria that rarely sicken healthy people but can be deadly for vulnerable patients already hospitalized with serious illnesses.

12 Jan 2023

IBS-related changes revealed using real time recording with a wearable device

Irritable bowel syndrome (IBS) is a difficult disease to treat, characterized by chronic abdominal pain related to bowel movements, of which there are four types: diarrheal, constipation, mixed, and unclassifiable.

12 Jan 2023

BioGrad to open the UK's second largest biobank facility in Liverpool as part of a £7.6m investment into new headquarters

BioGrad is to open the UK's second largest biobank facility in Liverpool, as part of a £7.6m investment into a new headquarters at Wavertree Technology Park.

From BioGrad 12 Jan 2023

Despite doctors’ concerns, University of California renews ties with religious affiliates

As the University of California's health system renews contracts with hundreds of outside hospitals and clinics — many with religious affiliations — some of its doctors and faculty want stronger language to ensure that physicians can perform the treatments they deem appropriate, including abortions for women or hysterectomies for transgender patients.

12 Jan 2023

Bleeding and in pain, a pregnant woman in Louisiana couldn’t get answers

When Kaitlyn Joshua found out she was pregnant in mid-August, she and her husband, Landon Joshua, were excited to have a second baby on the way. They have a 4-year-old daughter and thought that was just the right age to help with a younger sibling.

12 Jan 2023

Newly revised classification tool for standardized diagnostic reporting of melanocytic lesions

With the growing number of skin biopsies performed annually for suspected melanoma, a simple, easily understood standardized classification system for melanocytic lesions is increasingly important to aid pathologists and clinicians who examine millions of tissue samples each year and to alleviate patient confusion and anxiety.

11 Jan 2023

Medicine News and Research

Comprehensive atlas of protein kinases could help scientists decipher many cellular signaling pathways

COVID-19 booster doses could significantly reduce the incidence of SARS-CoV-2 infection among young adults

Brain structures could predict an person's predisposition to accidental awareness under anesthesia

Caterpillars could be used as an alternative to mammalian models to study gut inflammation

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

Reshaping the gut microbiome could be a possible way to prevent or treat neurodegeneration

New insights into deadly fungal invasion in people with compromised immune systems

Machine learning-based behavioral intervention can improve end-of-life cancer care

Social isolation is a risk factor for dementia in community-dwelling older adults, studies show

Study reveals how new cells join existing tissues by reading mechanical information

ADDF-Harrington partnership accelerates the translation of innovative Alzheimer's research into therapies

Breast milk of people vaccinated against COVID-19 provides protection to infants, study reveals

How might healthcare transform in the next 50 years?

Immunotherapy prior to surgery strikingly effective for patients with colorectal cancer

Screening patients for hidden reservoirs of bacteria could supplement infection-control efforts in hospitals

IBS-related changes revealed using real time recording with a wearable device

BioGrad to open the UK's second largest biobank facility in Liverpool as part of a £7.6m investment into new headquarters

Despite doctors’ concerns, University of California renews ties with religious affiliates

Bleeding and in pain, a pregnant woman in Louisiana couldn’t get answers

Newly revised classification tool for standardized diagnostic reporting of melanocytic lesions

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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