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Anti-HIV vaginal gel shows promise

An investigational vaginal gel intended to prevent HIV infection in women has demonstrated encouraging signs of success in a clinical trial conducted in Africa and the United States.

9 Feb 2009

Idenix Pharmaceuticals and GSK sign agreement for novel NNRTI for treatment of HIV

Idenix Pharmaceuticals, Inc. and GlaxoSmithKline (GSK) today announced the execution of a license agreement granting GSK exclusive worldwide rights to IDX899.

8 Feb 2009

Sangamo BioSciences starts trial of CCR5-ZFP therapeutic to treat HIV/AIDS

Sangamo BioSciences, Inc. has announced that its collaborators at the University of Pennsylvania have opened a Phase 1 clinical trial to evaluate SB-728-T for the treatment of HIV/AIDS.

5 Feb 2009

Many neglected diseases lacking research funding

The first comprehensive survey of global spending on neglected disease R&D, published in this week's PLoS Medicine , finds that just over $US 2.5 billion was invested into R&D of new products in 2007, with three diseases-HIV/AIDS, TB, and malaria-receiving nearly 80% of the total

5 Feb 2009

Robot scientist promises to dig up new drugs

A robot scientist that can make informed guesses about how effective different chemical compounds will be at fighting different diseases could revolutionise the pharmaceutical industry by developing more effective treatments more cheaply and quickly than current methods.

3 Feb 2009

Computer writing programs make writing easier for persons with aphasia

Aphasia affects the ability to understand and use spoken language, and the ability to read and write. Persons with aphasia were trained in the use of computerised writing aids in the study on which speech and language pathologist Ingrid Behrns' doctoral thesis is based. The subjects were aided by a computer-based spell-checker and a program for word prediction, similar to that used when writing SMS messages on mobile telephones.

3 Feb 2009

Brain cells called astrocytes, not neurons, lull the brain to sleep

Brain cells called astrocytes help to cause the urge to sleep that comes with prolonged wakefulness, according to a study in mice, funded by the National Institutes of Health.

2 Feb 2009

The immune system's hidden talents

Half of the immune system has a hidden talent, researchers at Washington University School of Medicine in St. Louis have discovered.

27 Jan 2009

Health IT associated with better outcomes, lower costs

Patients at Texas hospitals that have automated some aspects of their health information systems appear to have fewer complications, lower death rates and reduced costs, according to a report in the January 26 issue of Archives of Internal Medicine , one of the JAMA/Archives journals.

27 Jan 2009

Waging war on tropical diseases may be key to U.S. foreign policy

Stating that neglected tropical diseases (NTDs) not only promote poverty but also destabilize communities, former Health and Human Services Secretary Tommy Thompson and Sabin Vaccine Institute President Peter Hotez call upon the public-health and foreign-policy communities to embrace medical diplomacy and NTD control as a means to combat terrorism in an article published January 27 in the open-access journal PLoS Neglected Tropical Diseases.

27 Jan 2009

Potential new target in the war on HIV/AIDS

The study revealed that a variant of a protein involved in HIV pathogenesis can suppress production of an HIV protein, known as Nef. Nef is required for the human immunodeficiency virus to develop into AIDS through a series of complex events involving viral elements and cellular proteins. Nef has never been a target for drug treatment in HIV patients.

21 Jan 2009

Topical microbicide protects against genital herpes

A topical microbicide that silences two genes can safely protect against genital herpes infection for as long as one week, according to a joint study by researchers at the Albert Einstein College of Medicine of Yeshiva University and Harvard Medical School.

21 Jan 2009

Sharp increase in use of prescription sleep aids by young adults

Use of prescription sleep aids nearly tripled among 18- to 24-year-olds between 1998 and 2006, according to a study released today by the Healthcare business of Thomson Reuters.

19 Jan 2009

Mutant host cell protein sequesters critical HIV-1 element

Scientists have identified a new way to inhibit a molecule that is critical for HIV pathogenesis.

19 Jan 2009

A tipple a day helps seniors keep disabilities at bay

It is well known that moderate drinking can have positive health benefits - for instance, a couple of glasses of red wine a day can be good for the heart.

19 Jan 2009

New hope for transplant recipients and AIDS patients

A researcher from the Université de Montréal and the Maisonneuve-Rosemont Hospital has discovered the mechanism that prevents the regeneration of CD4+ T lymphocytes, which are white cells that are required for the proper functioning of the immune system.

12 Jan 2009

Gold particles and infrared light for controlled drug delivery

Using tiny gold particles and infrared light, MIT researchers have developed a drug-delivery system that allows multiple drugs to be released in a controlled fashion.

1 Jan 2009

HIV carriers in Malaysia should not be allowed to marry, says government official

One of Malaysia's top politicians has apparently suggested that HIV carriers should not be allowed to marry in order to avoid having sick children.

22 Dec 2008

Physicians perform rare surgery to restore hearing to a deaf patient

Marisela Leon, 44, has neurofibromatosis type 2 -- a rare genetic condition that causes tumors to grow on nerves in the brain or spinal cord, but most commonly on the auditory nerve. Leon lost her hearing more than four years ago when surgery to remove a tumor damaged her auditory nerve.

22 Dec 2008

Voriconazole effective in combating fungal infections

The effectiveness of voriconazole in combating fungal infections has been confirmed by a new study to be featured in the International Journal of Antimicrobial Agents, published by Elsevier.

16 Dec 2008