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Combination of high-intensity ultrasound and immunotherapy may be effective in treating cancer

In a new study published today in JCI Insight, UC Davis researchers have shown that combining high-intensity focused ultrasound with two immunotherapies (a PD-1 checkpoint inhibitor and TLR9 agonist) can produce excellent response rates in mouse models of epithelial cancer.

25 Mar 2017

Major grant funds research effort that seeks to understand complexity of invasive cancer

A $9.5 million, five-year grant from the National Cancer Institute (NCI) will fund an intensive multidisciplinary research effort that seeks to better understand how cancer cells reach an aggressive state and begin to damage surrounding tissue.

25 Mar 2017

Immunotherapy drug becomes first FDA-approved treatment for metastatic MCC

The U.S. Food and Drug Administration yesterday granted accelerated approval to the checkpoint inhibitor Bavencio (avelumab) for the treatment of patients with metastatic Merkel cell carcinoma (MCC), including those who have not received prior chemotherapy.

25 Mar 2017

Researchers pinpoint Jumonji protein as key to Ewing's Sarcoma spread

By the time Ewing's Sarcoma is diagnosed, primarily in teens and young adults, it has often spread from its primary site to other parts of the body, making it difficult to treat.

24 Mar 2017

Berkeley researchers search for cancer clues in sample of blood

One day, patients may be able to monitor their body's response to cancer therapy just by having their blood drawn. A new study, led by bioengineers at UC Berkeley, has taken an important step in that direction by measuring a panel of cancer proteins in rare, individual tumor cells that float in the blood.

24 Mar 2017

Study reveals intriguing crosstalk between metabolism and epigenetics in cancer development

A study published in Briefings in Functional Genomics investigated how epigenetics can modulate human's genetic program -- it can emphasize or silence genes.

24 Mar 2017

MSK scientists discover epigenetic mechanism promoting breast cancer

Researchers from Memorial Sloan Kettering Cancer Center (MSK) have identified, for the first time, an epigenetic mechanism promoting breast cancer.

24 Mar 2017

Scientists developing novel imaging techniques to provide immediate diagnoses for cancer patients

Neurosurgeons at The Barrow Neurological Institute (BNI), North America’s largest neurosurgical training program and scientists at The Arizona State University Biodesign Institute (ASU), in collaboration with Zeiss Microscopy are developing novel molecular nanoprobes and cutting-edge optical imaging techniques to provide immediate and specific diagnoses for cancer patients.

24 Mar 2017

New clinical approach offers hope for patients with aggressive brain cancer

Being diagnosed with a malignant brain tumor is devastating news for patients and their loved ones. Whereas some types of tumor respond well to treatment, others such as glioblastomas - the most common and aggressive brain tumors - are known to recur and progress within short times from the diagnosis.

23 Mar 2017

FDA grants accelerated approval to new drug for treatment of rare form of skin cancer

The U.S. Food and Drug Administration today granted accelerated approval to Bavencio (avelumab) for the treatment of adults and pediatric patients 12 years and older with metastatic Merkel cell carcinoma (MCC), including those who have not received prior chemotherapy.

23 Mar 2017

Genome sequencing approach opens door to therapy options for rare, neglected cancers

An international team of scientists led by the Icahn School of Medicine at Mount Sinai and UConn School of Medicine have reported the results of a genome sequencing study for an extremely rare form of cancer.

23 Mar 2017

Statin drugs may offer treatment option for chronic liver disease

Statin drugs are widely used to manage high cholesterol and reduce the risk of cardiovascular disease. But in a new review of more than 50 studies, researchers cite reductions in liver inflammation and improvements in other related factors as reasons why statins make good candidates for treating chronic liver disease.

23 Mar 2017

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Building on their previous research focusing on vaccination within a tumor (intratumoral) for the most common form of pancreatic cancer, investigators from Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School have shown that in a mouse model of early stage resected pancreatic cancer, intratumoral vaccination induces an anti-tumor response that results in a significant improvement in overall survival.

23 Mar 2017

Researchers examine potential for microRNAs to detect gastrointestinal cancer in blood, bodily fluids

Blood tests that could detect cancer before it develops show promise for the future of screening and prevention, though researchers continue to test which cancer clues are good markers for diagnosis.

22 Mar 2017

Machine learning helps researchers uncover cellular control networks

The flow of information between cells in our bodies is exceedingly complex: sensing, signaling, and influencing each other in a constant flow of microscopic engagements. These interactions are critical for life, and when they go awry can lead to the illness and injury.

22 Mar 2017

New technology may provide non-invasive approach to diagnose and monitor prostate cancer

Technology being developed at Washington State University provides a non-invasive approach for diagnosing prostate cancer and tracking the disease's progression.

22 Mar 2017

Study identifies potential Achilles heel of kinase-driven cancers

Scientists identify two signaling proteins in cancer cells that make them resistant to chemotherapy, and show that blocking the proteins along with chemotherapy eliminate human leukemia in mouse models.

22 Mar 2017

New study correlates 80 cancer-related gene mutations with 34 AML subgroups

A large, new study of adults with acute myeloid leukemia (AML) correlates 80 cancer-related gene mutations with five subtypes of AML, which are defined by the presence of specific chromosomal abnormalities. The findings might help guide mutation testing and treatment decisions in the future.

21 Mar 2017

Chemists develop biosafe luminescent nanoparticles for imaging tumors and blood vessels

Chemists from Russia and Switzerland created biosafe luminescent nanoparticles for imaging tumors and blood vessels damaged by heart attack or stroke.

21 Mar 2017

Duke scientists use mathematical tools to track how microbial evolution unfolded

As the human species evolved over the last six million years, our resident microbes did the same, adapting to vastly different conditions on our skin and in our mouths, noses, genitalia and guts.

21 Mar 2017

Tumor News and Research

Combination of high-intensity ultrasound and immunotherapy may be effective in treating cancer

Major grant funds research effort that seeks to understand complexity of invasive cancer

Immunotherapy drug becomes first FDA-approved treatment for metastatic MCC

Researchers pinpoint Jumonji protein as key to Ewing's Sarcoma spread

Berkeley researchers search for cancer clues in sample of blood

Study reveals intriguing crosstalk between metabolism and epigenetics in cancer development

MSK scientists discover epigenetic mechanism promoting breast cancer

Scientists developing novel imaging techniques to provide immediate diagnoses for cancer patients

New clinical approach offers hope for patients with aggressive brain cancer

FDA grants accelerated approval to new drug for treatment of rare form of skin cancer

Genome sequencing approach opens door to therapy options for rare, neglected cancers

Statin drugs may offer treatment option for chronic liver disease

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Researchers examine potential for microRNAs to detect gastrointestinal cancer in blood, bodily fluids

Machine learning helps researchers uncover cellular control networks

New technology may provide non-invasive approach to diagnose and monitor prostate cancer

Study identifies potential Achilles heel of kinase-driven cancers

New study correlates 80 cancer-related gene mutations with 34 AML subgroups

Chemists develop biosafe luminescent nanoparticles for imaging tumors and blood vessels

Duke scientists use mathematical tools to track how microbial evolution unfolded

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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