Bile News and Research

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Omega-3 fatty acids inhibit the growth of liver cancer cells

Two new studies by a University of Pittsburgh research team suggest that omega-3 fatty acids - substances that are found in high concentrations in fish oils and certain seeds and nuts - significantly inhibit the growth of liver cancer cells.

3 Apr 2006

University of Michigan researchers target stubborn gram-negative bacteria

Ronald Woodard's team set out looking for a way to kill a stubborn type of bacteria and they succeeded - but not in the way he expected.

9 Mar 2006

New children's heart valve

New valves and stents made of super-elastic, shape-memory metal alloy combined with less invasive procedure mean quicker recovery for children with heart disease.

16 Feb 2006

Gut protein protects against infection and intestinal breakdown

A protein that binds to bile in the small intestine may hold the key to preventing infection and intestinal breakdown in people with conditions such as obstructive jaundice or irritable bowel syndrome, researchers at UT Southwestern Medical Center have discovered.

12 Feb 2006

New pathways linking liver disease to changes in the central nervous system

Liver disease is often associated with "sickness behaviors," such as malaise, listlessness, anorexia, difficulty concentrating, and fatigue. In cholestatic liver diseases (where bile production is impaired) such as primary biliary cirrhosis, fatigue occurs in up to 86 percent of patients.

5 Jan 2006

Wide variation in the use of laparoscopic surgery for gall bladder removal

There is a wide variation in the use of laparoscopic surgery for gall bladder removal in Hong Kong hospitals, and use of this procedure is more likely at certain hospitals and among younger female patients operated on more recently, according to a study in the Archives of Surgery.

7 Dec 2005

Liver transplants may not be suitable for all cystic fibrosis patients

A new study on patients with cystic fibrosis (CF) who have had abnormal bleeding from ruptured blood vessels in the esophagus (variceal hemorrhage) as a result of liver disease found that transplant may not be indicated if there are no other indications of advanced liver disease.

5 Dec 2005

New hormone discovery has implications for liver diseases

Researchers at UT Southwestern Medical Center have discovered that the small intestine communicates with the liver to control the production of bile acids - a finding that has great medical implications in treating people at risk for certain types of liver disease.

11 Oct 2005

Newly discovered hormone plays an important role in the digestion of fat, cholesterol, and fat-soluble vitamins

A newly discovered hormone plays an important role in the digestion of fat, cholesterol, and fat-soluble vitamins, such as vitamins A, E, and D, according to a new study in the October 2005 issue of Cell Metabolism.

11 Oct 2005

Combining radiation, chemotherapy and liver transplantation increases survival in bile duct cancer patients

A new treatment for patients with a type of bile duct cancer promises a greater chance at survival by combining radiation, chemotherapy and liver transplantation, Mayo Clinic physicians report in the September issue of the Annals of Surgery.

12 Sep 2005

Patients with primary biliary cirrhosis who are treated with methotrexate have an increased risk of death

In five randomized controlled trials involving 457 people, the authors report that for patients treated with methotrexate, as a single therapy or in combination with other drug treatment, pooled data showed a tendency toward an increased risk of death or liver transplantation. The brand names for methotrexate are Rheumatrex and Trexall.

23 Aug 2005

A study analyzes the most important factors leading to death or liver transplant in drug-induced liver disease

Drug-induced liver disease (DILD), a potential complication seen with some medications, is usually not life-threatening, but may occasionally be more severe with a high mortality, requiring a liver transplant in selected cases.

18 Jul 2005

Cordis release new stent featuring the latest advancement in balloon-expandable stent technology

Cordis Endovascular, today announced the U.S. launch of the PALMAZ(R) BLUE(TM) Transhepatic Biliary Cobalt Chromium Stent, the latest advancement in balloon-expandable stent technology. Featuring L605, a cobalt alloy enhanced with tungsten, the PALMAZ(R) BLUE(TM) Stent is stronger than stainless steel stents and uses less metal.

1 Jul 2005

Researchers discover genetic trigger that plays a key role in cancer of the oesophagus

Cancer Research UK scientists at the University of Oxford have identified a gene which plays a key role in the development of cancer of the oesophagus by triggering changes in the oesophagus lining.

24 May 2005

Global project to combat parasites that cause cancer and infection in millions

Many cancers are associated with infections (for example cervical cancer is linked to the human papilloma virus) but there is no stronger link between a human malignancy and a parasitic infection than that between cancer of the bile ducts and a liver fluke called Opisthorchis viverrini.

18 May 2005

Self-expanding metal tubes or stents are a safe and effective treatment for obstructive jaundice

One key goal of treating pancreatic cancer, which is often fatal within a year, is making sure patients have a good quality of life with as few complications as possible. This is especially important if they are candidates for surgical removal of the cancer.

2 May 2005

Immune cells in the liver travel in the liver's blood vessels with surprising speed and agility

Scientists at New York University School of Medicine viewing the actual journey of immune cells in the liver have found that these cells travel in the liver's blood vessels with surprising speed and agility.

4 Apr 2005

Elevated glucose levels and diabetes associated with a greater risk for cancer

New research involving more than one million people indicates that having high fasting serum glucose levels and diabetes are risk factors for several major cancers, according to a study in the January 12 issue of JAMA.

12 Jan 2005

Experimental compound prevents cholesterol gallstone disease

A promising experimental compound prevents cholesterol gallstone disease in mice by stimulating the biochemical pathway that controls bile acid secretion by the liver, according to new studies by Howard Hughes Medical Institute researchers.

23 Nov 2004

Novel treatment of patients with high cholesterol focus of national meeting

Implications of recent lipid-lowering clinical trials and the specific changes to the NCEP guidelines will be the focus of discussion by Neil J. Stone, M.D., professor of clinical medicine of the Feinberg School of Medicine at Northwestern University.

6 Aug 2004