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TGen scientists identify potent inhibitory compound for treatment against glioblastoma

A study led by scientists at the Translational Genomics Research Institute has identified "a potent inhibitory compound" in the elusive hunt for an improved treatment against glioblastoma, the most common and deadly type of adult brain cancer.

18 Jan 2017

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

An enzyme identified in Saccharomyces cerevisiae, commonly known as brewer's or baker's yeast, has passed in vitro trials, demonstrating its capacity to kill acute lymphoblastic leukemia (ALL) cells.

18 Jan 2017

Researchers identify brain cell types from cell culture of adult human neurons

Studying brain disorders in people and developing drugs to treat them has been slowed by the inability to investigate single living cells from adult patients

18 Jan 2017

Inactive B2M genes can condition response of lung cancer patients to immunotherapy, study shows

Researchers from the Genes and Cancer research group at the Bellvitge Biomedical Research Institute have identified inactivating mutations in a number of genes that code for HLA-I histocompatibility complex proteins, which are involved in the immune response and can condition the tesponse of lung cancer patients to immunotherapy.

18 Jan 2017

Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

17 Jan 2017

Common drug for high blood pressure repurposed to treat soft tissue sarcoma in Europe

A drug that's commonly used to treat high blood pressure is being repurposed for a rare tissue cancer in Europe. The medication, named propranolol, was recently granted Orphan Drug Designation by the European Commission.

17 Jan 2017

Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

Each day, more than 1,600 people die from cancer in the US, and 450 in the UK, mostly because the disease has spread beyond a stage when surgery is an effective cure and has become resistant to therapy. Despite decades of research, understanding why cancer cells become invasive has remained shrouded in mystery.

17 Jan 2017

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Massachusetts General Hospital investigators have identified a protein that may play an essential role in maintaining a population of tumor-initiating cells (TICs) -- treatment-resistant cells responsible for cancer recurrence and metastasis -- in breast cancer, as well as a compound that appears to reduce the molecule's ability to protect TICs from the effects of chemotherapy.

17 Jan 2017

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Metastatic pancreatic cancer -- cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths -- changes its metabolism and is "reprogrammed" for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

16 Jan 2017

NovaSeq, the new sequencer by Illumina, said to transform the field of genomics

Illumina, Inc., the global leader in next-generation sequencing technology, today introduced the NovaSeqTM Series, a new and scalable sequencing architecture expected one day to enable a $100 genome. Unveiled at the J.P. Morgan Healthcare Conference, this platform redefines high throughput sequencing with unrivaled throughput, ease of use, low per sample costs, and unmatched flexibility.

From Illumina, Inc. 12 Jan 2017

Novel treatment can effectively inhibit development of GVHD in mice, study shows

Graft-versus-host-disease (GVHD) is the leading cause of non-relapse associated death in patients who receive stem cell transplants.

12 Jan 2017

Epigenetic modification may be cause of adult throat cancers linked to alcohol, tobacco use

A team of researchers at the Research Institute of the McGill University Health Centre has found an epigenetic modification that might be the cause of 15% of adult cancers of the throat linked to alcohol and tobacco use.

12 Jan 2017

MUSC scientists design novel antibody-based therapy to fight against cancer

Scientists at the Medical University of South Carolina (MUSC) have designed an antibody-based therapy that could target the functions of TGF-beta that cause cancer

12 Jan 2017

Duke researchers use cancer-seeking salmonella to treat glioblastoma

Biomedical engineers at Duke University have recruited an unlikely ally in the fight against the deadliest form of brain cancer -- a strain of salmonella that usually causes food poisoning.

11 Jan 2017

UCM scientists design biosensor capable of detecting cancer autoantibodies at early stages

Before a malignant tumor is developed, the immune system tries to fight against proteins that are altered during their formation, producing certain cancer antibodies.

11 Jan 2017

Illumina and IBM join forces to grow accessibility to genome data interpretation

IBM Watson Health and Illumina, Inc. today announced a groundbreaking partnership to expand access to genome data interpretation by integrating Watson for Genomics into Illumina’s BaseSpace Sequence Hub and tumor sequencing process. The collaboration is designed to help standardize and simplify genomic data interpretation.

From Illumina, Inc. 11 Jan 2017

Researchers identify sub-population of HIV-1 strains with biological properties to transmit new infections

Upon sexual exposure, the AIDS virus must overcome some mighty barriers to find the right target cell and establish a new infection.

11 Jan 2017

Researchers identify new subgroup of cervical cancers with different genetic features

A team of University of South Carolina scientists led by Carolyn Banister and Phillip Buckhaults has identified a new subtype of cervical cancer that, like most cervical cancers, is triggered by human papillomavirus (HPV) but whose growth is not directed by the virus, suggesting that therapy targeting these tumors' distinct genomic pathways may improve patient outcomes over standard treatment.

11 Jan 2017

KIT researchers prove that neurons regulate blood vessel growth

A team of researchers at Karlsruhe Institute of Technology shake at the foundations of a dogma of cell biology.

10 Jan 2017

Study reveals importance of glutamine metabolism for colon cancer

The importance of glutamine was made clear as a colon cancer specific metabolism. It is known that glutamine metabolism is important for pancreatic cancer, but the importance of glutamine metabolism for colon cancer has been unclear.

10 Jan 2017

Tumor News and Research

TGen scientists identify potent inhibitory compound for treatment against glioblastoma

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

Researchers identify brain cell types from cell culture of adult human neurons

Inactive B2M genes can condition response of lung cancer patients to immunotherapy, study shows

Epigenetic changes drive successful metastases of pancreatic cancer cells

Common drug for high blood pressure repurposed to treat soft tissue sarcoma in Europe

Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

NovaSeq, the new sequencer by Illumina, said to transform the field of genomics

Novel treatment can effectively inhibit development of GVHD in mice, study shows

Epigenetic modification may be cause of adult throat cancers linked to alcohol, tobacco use

MUSC scientists design novel antibody-based therapy to fight against cancer

Duke researchers use cancer-seeking salmonella to treat glioblastoma

UCM scientists design biosensor capable of detecting cancer autoantibodies at early stages

Illumina and IBM join forces to grow accessibility to genome data interpretation

Researchers identify sub-population of HIV-1 strains with biological properties to transmit new infections

Researchers identify new subgroup of cervical cancers with different genetic features

KIT researchers prove that neurons regulate blood vessel growth

Study reveals importance of glutamine metabolism for colon cancer

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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