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Scientists uncover the structure of the first step in amyloid formation for Huntington's disease

Devastating neurodegenerative diseases like Huntington's, Alzheimer's, and Parkinson's are all associated with protein deposits in the brain, known as amyloid.

13 Jun 2023

Beyond exhaustion: study identifies fatigue as key factor limiting functionality in long COVID patients

Researchers assess self-documented long COVID symptoms among care-seeking individuals.

13 Jun 2023

Study findings could reassure most women treated for early breast cancer

Most women diagnosed with early stage breast cancer today can expect to become long term cancer survivors, finds a study published by The BMJ today.

13 Jun 2023

Repeat intraocular corticosteroid injections improve vision in people with persistent or recurrent uveitic macular edema

Repeat treatment with corticosteroid injections improved vision in people with persistent or recurrent uveitis-related macular edema better than two other therapies, according to results from a clinical trial funded by the National Eye Institute.

13 Jun 2023

Study reveals biologically validated imaging-based evidence of medically induced myelin repair

A decade after UC San Francisco scientists identified an over-the-counter antihistamine as a treatment for multiple sclerosis, researchers have developed an approach to measure the drug's effectiveness in repairing the brain, making it possible to also assess future therapies for the devastating disorder.

13 Jun 2023

Scientists find clues to how we maintain constant blood sugar levels after meals

Scientists from the Berlin Institute of Health at Charité (BIH), along with colleagues from the United Kingdom, have found clues as to how we maintain constant blood sugar levels after we have eaten.

12 Jun 2023

Study offers novel insights into the evolution of multiple myeloma

A new study by researchers at The University of Texas MD Anderson Cancer Center highlights novel insights into the evolution of multiple myeloma from precursor disease, which may help better identify patients likely to progress and develop new interventions.

12 Jun 2023

$78.4 million NIH grant supports Tufts CTSI to advance clinical and translational science research

Tufts Clinical and Translational Science Institute has received a $78.4 million Clinical and Translational Science Award from the NIH, the fourth consecutive grant since its founding in 2008.

10 Jun 2023

PREACH-M trial: Lenzilumab may improve treatment response in chronic myelomonocytic leukemia

Humanigen, Inc.today extended previously reported results by presenting additional, statistically significant hematologic improvements and reductions in inflammatory markers from lenzilumab, its investigational drug, in a Phase 2/3 trial of treatment-naïve participants with chronic myelomonocytic leukemia and RAS-pathway mutations.

9 Jun 2023

Innovative 'village in a dish' system can accelerate stem cell research

A powerful new stem cell technique has enabled large-scale studies of the relationship between human genetics and biology.

9 Jun 2023

Study may help advance data on oncolytic adenovirus mediated double suicide-gene therapy for high-grade brain tumors

Researchers in the Hermelin Brain Tumor Center at Henry Ford Health are leading a Phase I clinical trial studying the maximum tolerated dose of an oncolytic adenovirus, a mutated virus engineered to selectively replicate in and destroy cancer tissue, in combination with fractionated stereotactic radiosurgery among patients who are undergoing resection of a recurrent high-grade astrocytoma brain tumor.

8 Jun 2023

First-in-class drug shows promise as a safe and effective treatment for cannabis use disorder

A first-in-class drug engineered to selectively inhibit the signaling pathway of the cannabinoid receptor shows promise as a safe and effective treatment for cannabis use disorder (CUD), a condition where a person is unable to control their cannabis use, even though it's causing problems in their lives.

8 Jun 2023

Global study provides high-quality data to improve treatment of newborn babies with sepsis

A global observational study, which involved more than 3,200 newborn babies suffering from sepsis in 19 hospitals in 11 countries, has shown that many newborns are dying because the antibiotics used to treat sepsis are losing their effectiveness.

8 Jun 2023

DNA study sheds light on how we maintain healthy blood sugar levels after meals

A study of the DNA of more than 55,000 people worldwide has shed light on how we maintain healthy blood sugar levels after we have eaten, with implications for our understanding of how the process goes wrong in type 2 diabetes.

8 Jun 2023

Sebum RNA could provide reliable biomarkers for detecting early-onset atopic dermatitis

Eczema is an inflammatory skin condition that often affects infants as young as one to two months. Among the various types of eczema seen in infants, early-onset atopic dermatitis (AD), characterized by psychological stress and sleep disorders, is particularly concerning.

8 Jun 2023

Teaming up with the patient’s immune system to combat cancer

The fact that our immune systems capture and destroy nanoparticles and the drugs they carry has been a problem in the field of nanomedicine for some time. But, in the fight against cancer, researchers are now attempting to exploit this problem to their advantage.

8 Jun 2023

UVA scientists discover a key determinant of multiple sclerosis risk

University of Virginia School of Medicine scientists have discovered a key determinant of our risk for multiple sclerosis (MS), advancing efforts to prevent and better treat the disease.

7 Jun 2023

Ancient, virus-like protein may contribute to ALS

More than 5,000 people are diagnosed annually with ALS (amyotrophic lateral sclerosis), a fatal, neurodegenerative disease that attacks nerve cells in the brain and spinal cord, gradually robbing people of the ability to speak, move, eat and breathe.

7 Jun 2023

Estimate of treatment effect modification by comorbidity using participant data

Treatment efficacy for a broad range of chronic diseases does not differ depending on patients' comorbidities, according to a new study publishing June 6th in the open access journal PLOS Medicine by David McAllister of the University of Glasgow, UK, and colleagues.

7 Jun 2023

Spinal neural circuit dysfunction mediates movement symptoms in dystonia

Many neurological conditions that involve involuntary muscle contractions have long been considered as diseases of the brain.

6 Jun 2023

Medical Research News and Research

Scientists uncover the structure of the first step in amyloid formation for Huntington's disease

Beyond exhaustion: study identifies fatigue as key factor limiting functionality in long COVID patients

Study findings could reassure most women treated for early breast cancer

Repeat intraocular corticosteroid injections improve vision in people with persistent or recurrent uveitic macular edema

Study reveals biologically validated imaging-based evidence of medically induced myelin repair

Scientists find clues to how we maintain constant blood sugar levels after meals

Study offers novel insights into the evolution of multiple myeloma

$78.4 million NIH grant supports Tufts CTSI to advance clinical and translational science research

PREACH-M trial: Lenzilumab may improve treatment response in chronic myelomonocytic leukemia

Innovative 'village in a dish' system can accelerate stem cell research

Study may help advance data on oncolytic adenovirus mediated double suicide-gene therapy for high-grade brain tumors

First-in-class drug shows promise as a safe and effective treatment for cannabis use disorder

Global study provides high-quality data to improve treatment of newborn babies with sepsis

DNA study sheds light on how we maintain healthy blood sugar levels after meals

Sebum RNA could provide reliable biomarkers for detecting early-onset atopic dermatitis

Teaming up with the patient’s immune system to combat cancer

UVA scientists discover a key determinant of multiple sclerosis risk

Ancient, virus-like protein may contribute to ALS

Estimate of treatment effect modification by comorbidity using participant data

Spinal neural circuit dysfunction mediates movement symptoms in dystonia

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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