Structural Biology News and Research

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Scientist rewarded for breaking down transplant rejection

A scientist from Australia's Monash University who has recently determined the structure of drug that is widely used as an immunosuppressant, will be presented the 2004 Science Minister's Prize for Life Scientist of the Year.

8 Sep 2004

Experts consider evidence of link between the rise in childhood leukaemia and increased light at night

International experts will today consider the evidence for a link between the rise in childhood leukaemia and increased light at night at an international scientific conference in London.

8 Sep 2004

International research sheds light on Escherichia coli

An unprecedented picture of how bacteria latch on to human cells has been published by UK, French and US scientists. They have produced a finely detailed model of one of the tools used by some of the nastiest varieties of the stomach bug, Escherichia coli, to stick to and gain entry to host cells.

1 Sep 2004

Researchers have identified a possible cause of an inherited form of Parkinson's disease

Columbia University Medical Center and Albert Einstein College of Medicine researchers have identified a possible cause of an inherited form of Parkinson's disease, which may be related to more common forms of the disease.

26 Aug 2004

Enzyme activation key to body clock

Feel like time is repeating itself and won’t move on? It could be your internal clock is backpedaling because your PKG-II is out of whack.

20 Aug 2004

Researchers map structure of anti-cancer molecule and open the door to the creation of more effective cancer treatments

Scientists at Emory University, in collaboration with researchers at three national laboratories, have solved the structural puzzle of how an emerging class of promising cancer drugs works to halt cell division. The discovery potentially opens the door to the creation of more effective cancer treatments.

13 Aug 2004

Automated science speeds solution of Human Genome data

Scientists in Argonne's Biosciences Division are automating and accelerating the complex processes that coax a protein to reveal its structure so they can learn the role Nature assigned it.

6 Aug 2004

New compound that is designed to overcome Gleevec resistance

One of the truly spectacular success stories in modern oncology is the development and implementation of Gleevec, a drug that virtually halts the progress of chronic myeloid leukemia. Yet for some patients who harbor particularly stubborn genetic mutations, Gleevec fails miserably.

17 Jul 2004

Scientists determine structure of staph, anthrax enzyme

Researchers at the U.S. Department of Energy's Argonne National Laboratory and the University of Chicago have determined the crystal structure of sortase B, an enzyme found in the bacteria that cause staph and anthrax. While an antibiotic is probably five to seven years away, the structure could provide the first clue in developing a treatment for the infections.

15 Jul 2004

Learning about protein structure is especially relevant for treating illnesses that alter protein function

The field of structural genomics - the study of the three dimensional geometric structures of proteins - is complicated by vast amounts of data, expensive experiments and cumbersome methods of analysis.

24 Jun 2004

Australia's CSIRO to exhibit major display at the world's largest biotechnology conference

CSIRO is mounting a major display of technologies this week at BIO 2004, the world's largest biotechnology conference, being held in San Francisco, USA, from 6-9 June.

7 Jun 2004

Scientists have discovered an exciting new target in the fight to stop the spread of cancer cells

Scientists at The Institute of Cancer Research have discovered an exciting new target in the fight to stop the spread of cancer cells which could significantly improve treatment by replacing traditional chemotherapy.

20 Apr 2004

New tool for study of carbohydrates could aid drug research

While many dieters are trying to cut carbs, a University of New Hampshire (UNH) biochemist has invented a way to capture them so scientists can more easily study their structure.

13 Apr 2004

A new technique for engineering protein crystals is helping scientists figure out the three-dimensional structures of some important biological molecules

A new technique for engineering protein crystals is helping scientists figure out the three-dimensional structures of some important biological molecules, including a key plague protein whose structure has eluded researchers until now. The technique, developed with support from the National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health (NIH), promises to help pharmaceutical companies develop more effective drugs to treat various diseases by tailor-making molecules to "fit" a protein's shape.

6 Apr 2004