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Retinoblastoma protein plays larger role in tumor suppression, study finds

The Retinoblastoma protein (pRB) has long been studied for its role in cell growth and the prevention of cancer.

16 Dec 2016

Study suggests revolutionary way to make cancer cells more susceptible to existing chemotherapies

The same signal that drives aggressive growth in a deadly cancer cell type also triggers coping mechanisms that make it "notoriously" hard to kill, according to a study published online December 15 in Cell. When stressed, this cell type - far more than most cancer cells - encases its genetic messages in protein globs called "stress granules" that lessen the effect of chemotherapies.

16 Dec 2016

Overexpression of nerve growth factor drives gastric tumorigenesis in mice

Gastric tumors are started by specialized cells in the stomach that signal nerves to make more acetylcholine, according to a study in mice.

16 Dec 2016

Researchers develop promising therapeutic antibodies against tumor-promoting MMPs

Researchers at the University of California, Riverside have camels and llamas to thank for their development of a new cancer treatment that is highly selective in blocking the action of faulty matrix metalloproteinases (MMPs).

16 Dec 2016

Researchers develop new method to identify antigens for cancer treatment

New cancer therapies harness the immune system to fight tumors. One of the main principles behind these therapies is to find out precisely which molecules on cancer cells trigger an immune response.

16 Dec 2016

Researchers identify attractive drug candidate to target glioma tumors

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed.

16 Dec 2016

WPI researchers develop chip to trap and identify metastatic cancer cells in blood

A chip developed by mechanical engineers at Worcester Polytechnic Institute can trap and identify metastatic cancer cells in a small amount of blood drawn from a cancer patient.

16 Dec 2016

Researchers use patient prostate tissue to create new model for cancer research

For the first time, researchers have been able to grow, in a lab, both normal and primary cancerous prostate cells from a patient, and then implant a million of the cancer cells into a mouse to track how the tumor progresses.

16 Dec 2016

Genes that control immune system play key role in predisposition to HPV-related tumors

A number of genetic variants associated with susceptibility to oral cavity and pharyngeal cancer have been described in an international study published in the journal Nature Genetics.

16 Dec 2016

Study improves molecular understanding of the brain in people with epilepsy

Neural stem cells have been found in epileptic brain tissue—outside the regions of the brain where they normally reside. In a group of patients who underwent surgery for epilepsy, over half had stem cells where healthy individuals do not have them, according to a study from Sahlgrenska Academy.

15 Dec 2016

Multifunctional RNA nanoparticles could overcome treatment resistance in breast cancer, study shows

Researchers at the University of Cincinnati College of Medicine have been able to generate multifunctional RNA nanoparticles that could overcome treatment resistance in breast cancer, potentially making existing treatments more effective in these patients.

15 Dec 2016

New technology that increases Natural Killer cells to stop cancers gets licensed

Our bodies contain Natural Killer (NK) cells - an army that stops cancers and viruses before they can make us sick.

15 Dec 2016

Lactate component responsible for anti-tumor effects of plasma medicine, research shows

Physical plasma is one of the four fundamental states of matter, together with solid, liquid, and gas, and can be completely or partially ionized (thermal/hot or non-thermal/cold plasma, respectively).

15 Dec 2016

Anti-platelet drug may slow spread of colon and pancreatic cancer cells

Researchers from Oregon Health and Science University have found that aspirin may slow the spread of some types of colon and pancreatic cancer cells. The paper is published in the American Journal of Physiology—Cell Physiology.

15 Dec 2016

Scientists explain concept of combining NO gas therapy with starvation of tumor cells for nanomedical treatment

Biocompatible nanocapsules, loaded with an amino acid and equipped with an enzyme now combine two anti-tumor strategies into a synergistic treatment concept. Researchers hope this increases effectiveness and decreases side effects.

14 Dec 2016

Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

A team of UCLA bioengineers has demonstrated that its technology may go a long way toward overcoming the challenges of treatment for acute lymphoblastic leukemia, among the most common types of cancer in children, and has the potential to help doctors personalize drug doses.

14 Dec 2016

Novel plasma medicine with anti-tumor effect discovered

Nagoya University researchers develop cold plasma-activated Ringer's solution for chemotherapy. The solution has anti-tumor effects in vitro and in vivo that derive from the lactate component.

14 Dec 2016

Cedars-Sinai surgeons use high-definition imaging device to map the brain during surgery

Cedars-Sinai neurosurgeons have begun using a high-definition imaging device to see inside the brain during surgery, allowing them to map safer pathways to reach and remove tumors.

9 Dec 2016

Two drug combinations may reduce mortality rates in breast cancer patients, study reveals

Patient health records revealed two drug combinations that may reduce mortality rates in breast cancer patients, according to a study led by researchers at the Stanford University School of Medicine.

9 Dec 2016

Image-guided percutaneous needle biopsies after NST identify breast cancer patients who achieve pCR

In a pilot study conducted at The University of Texas MD Anderson Cancer Center, image-guided biopsies identified select breast cancer patients who achieved pathologic complete response (pCR) after chemotherapy and/or targeted therapy, neoadjuvant systemic therapy (NST).

9 Dec 2016

Tumor News and Research

Retinoblastoma protein plays larger role in tumor suppression, study finds

Study suggests revolutionary way to make cancer cells more susceptible to existing chemotherapies

Overexpression of nerve growth factor drives gastric tumorigenesis in mice

Researchers develop promising therapeutic antibodies against tumor-promoting MMPs

Researchers develop new method to identify antigens for cancer treatment

Researchers identify attractive drug candidate to target glioma tumors

WPI researchers develop chip to trap and identify metastatic cancer cells in blood

Researchers use patient prostate tissue to create new model for cancer research

Genes that control immune system play key role in predisposition to HPV-related tumors

Study improves molecular understanding of the brain in people with epilepsy

Multifunctional RNA nanoparticles could overcome treatment resistance in breast cancer, study shows

New technology that increases Natural Killer cells to stop cancers gets licensed

Lactate component responsible for anti-tumor effects of plasma medicine, research shows

Anti-platelet drug may slow spread of colon and pancreatic cancer cells

Scientists explain concept of combining NO gas therapy with starvation of tumor cells for nanomedical treatment

Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

Novel plasma medicine with anti-tumor effect discovered

Cedars-Sinai surgeons use high-definition imaging device to map the brain during surgery

Two drug combinations may reduce mortality rates in breast cancer patients, study reveals

Image-guided percutaneous needle biopsies after NST identify breast cancer patients who achieve pCR

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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