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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Study offers potential new strategy for use of retinoids against some breast cancers

Estrogen-positive breast cancers are often treated with anti-estrogen therapies. But about half of these cancers contain a subpopulation of cells marked by the protein cytokeratin 5 (CK5), which resists treatment -- and breast cancers with higher CK5 expression have poorer prognosis.

26 Jul 2017

Gene's position on chromosome influences mutations, study shows

Genes do not exist in isolation. Like beads on a string, they sit next to each other on long DNA molecules called chromosomes.

25 Jul 2017

Researchers discover new virus in migratory bird species

Researchers at the University of São Paulo's Biomedical Science Institute (ICB-USP) in Brazil have discovered a new virus in a migratory bird species.

25 Jul 2017

African-American patients have increased gene mutations in tobacco-related tumors, study finds

African-Americans typically have worse outcomes from smoking-related cancers than Caucasians, but the reasons for this remain elusive. However, scientists at Wake Forest Baptist Medical Center have taken a big step toward solving this puzzle.

25 Jul 2017

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

Researchers from Genethon, the AFM-Telethon laboratory, Inserm (UMR 1089, Nantes) and the University of London (Royal Holloway) demonstrated the efficacy of an innovative gene therapy in the treatment of Duchenne muscular dystrophy.

25 Jul 2017

Princeton scientists test cell-culture system to aid study of HBV infections

Scientists from Princeton University's Department of Molecular Biology have successfully tested a cell-culture system that will allow researchers to perform laboratory-based studies of long-term hepatitis B virus (HBV) infections

25 Jul 2017

Counsyl unveils significant enhancements to expanded carrier screening panel

Counsyl, a DNA testing and genetic counseling company, today unveiled significant enhancements to its flagship expanded carrier screening product, Counsyl Foresight Carrier Screen, which uses next-generation sequencing technology to assess whether couples are at-risk for passing down serious genetic conditions to their children.

25 Jul 2017

Cellectis wins European patent for CRISPR use in T-cells

Cellectis, a clinical-stage biopharmaceutical company focused on developing immunotherapies based on gene-edited CAR T-cells (UCART), today announced the grant by the European Patent Office of patent No. EP3004337 for the invention of using RNA-guided endonucleases, such as Cas9 or Cpf1 for the genetic engineering of T-cells.

24 Jul 2017

Wistar scientists discover new therapeutic strategy for difficult-to-treat form of ovarian cancer

A potential new therapeutic strategy for a difficult-to-treat form of ovarian cancer has been discovered by Wistar scientists. The findings were published online in Nature Cell Biology.

24 Jul 2017

Diagnosing prostate cancer through a £225 urine test

This test, which we have branded SelectMDx for Prostate Cancer, came with the acquisition of a company in the Netherlands called NovioGendix. They developed a prototype assay, so they did most of the heavy lifting in terms of discovering the two specific biomarkers that are currently in the product. These biomarkers are tuned towards the detection of what I call clinically significant prostate cancer.

24 Jul 2017

Multistate Salmonella outbreak linked to Maradol Papaya: CDC reports

A total of 47 people have been infected with Salmonella Kiambu infections from 12 different states as of 21st July 2017, reports the CDC. Of these, 12 have had to be hospitalized and one person from New York City succumbed to the infection. Maradol papayas have been found to be the likely source of this infection and the CDC has recommended people not to consume these until its clear.

24 Jul 2017

First in-car study of rush hour pollution finds alarming results

The first in-car measurements of exposure to pollutants that cause oxidative stress during rush hour commutes has turned up potentially alarming results.

21 Jul 2017

New genomic research partnership promises to redefine and transform cancer treatment

Personalized cancer therapies are on the horizon thanks to a new genomic cancer research partnership between the Gene Editing Institute of Christiana Care Health System's Helen F. Graham Cancer Center & Research Institute and the biotechnology company NovellusDx.

21 Jul 2017

Novel model predicts single heart cell's response to dwindling supplies of oxygen

Time is of the essence when treating a patient undergoing a heart attack. Cardiac surgeons attempt to quickly stabilize the heart by applying reperfusion, a technique that restores oxygen to the heart by opening up blocked vessels with balloons and stents.

21 Jul 2017

Epigenetic dysregulation with age in normal breast tissue may contribute to cancer risk

Several known factors are associated with a higher risk of breast cancer including increasing age, being overweight after menopause, alcohol intake, and family history.

20 Jul 2017

Study identifies new mutations linked to hereditary neuroendocrine tumors

Pheochromocytomas and paragangliomas are rare neuroendocrine tumors with a strong hereditary component. Half the genes whose alterations confer hereditary susceptibility to develop this condition code for enzymes involved in the Krebs cycle, a metabolic route involved in cellular respiration.

20 Jul 2017

Genetic basis behind friendliness of dogs and humans uncovered in a new study

In a new study published in the journal Science Advances a connection was found between friendliness of dogs and a particular genetic makeup. Dogs differ from their closest cousins – wolves, in their friendliness towards humans and the gene that makes this possible has now been uncovered. This gene that allows for the hypersocial behaviour in dogs is also common in humans the study finds.

19 Jul 2017

CU Boulder study sheds new light on mechanism behind radiation-induced bystander effect

More than half of cancer patients undergo radiotherapy, in which high doses of radiation are aimed at diseased tissue to kill cancer cells.

19 Jul 2017

UD researchers receive $1 million Keck Foundation grant to dive deep into lives of microbes

Even in sediment cores extracted more than a mile beneath the ocean floor, you'll find them. Tiny organisms only a cell in size chug along ever so slowly.

19 Jul 2017

Researchers uncover new clues to why BRCA1 mutations cause breast and ovarian cancer

The human body holds many mysteries, and function of the BRCA1 gene is among them. Women who inherit a faulty copy of BRCA1 have up to a 65 percent chance to develop breast cancer by age 70. They also have up to a 39 percent chance to develop ovarian cancer.

19 Jul 2017

DNA News and Research

Further Reading

Study offers potential new strategy for use of retinoids against some breast cancers

Gene's position on chromosome influences mutations, study shows

Researchers discover new virus in migratory bird species

African-American patients have increased gene mutations in tobacco-related tumors, study finds

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

Princeton scientists test cell-culture system to aid study of HBV infections

Counsyl unveils significant enhancements to expanded carrier screening panel

Cellectis wins European patent for CRISPR use in T-cells

Wistar scientists discover new therapeutic strategy for difficult-to-treat form of ovarian cancer

Diagnosing prostate cancer through a £225 urine test

Multistate Salmonella outbreak linked to Maradol Papaya: CDC reports

First in-car study of rush hour pollution finds alarming results

New genomic research partnership promises to redefine and transform cancer treatment

Novel model predicts single heart cell's response to dwindling supplies of oxygen

Epigenetic dysregulation with age in normal breast tissue may contribute to cancer risk

Study identifies new mutations linked to hereditary neuroendocrine tumors

Genetic basis behind friendliness of dogs and humans uncovered in a new study

CU Boulder study sheds new light on mechanism behind radiation-induced bystander effect

UD researchers receive $1 million Keck Foundation grant to dive deep into lives of microbes

Researchers uncover new clues to why BRCA1 mutations cause breast and ovarian cancer

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