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T-DXd leads to longer overall survival in HER2-positive metastatic breast cancer patients than T-DM1

Second-line treatment with trastuzumab deruxtecan (T-DXd) led to significantly longer overall survival compared with trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer, according to updated results from the DESTINY-Breast03 phase III clinical trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

HIV transmission from mother to child can be stopped with modern antiviral drugs

Antiviral drugs almost completely reduce the risk of mothers passing on HIV infection to their children, even in a low-income country with a high HIV incidence such as Tanzania, according to a new study in The Lancet HIV by researchers from Karolinska Institutet.

7 Dec 2022

Cancer immunotherapies can become more potent depending on the time of day

Scientists from the UNIGE and LMU show that the anti-tumor activity of the immune system - and the effectiveness of cancer immunotherapies - depends on the time of day.

7 Dec 2022

Wearable technology could improve doctors' ability to administer precise medication doses

For some of the powerful drugs used to fight infection and cancer, there's only a small difference between a healing dose and a dose that's large enough to cause dangerous side effects.

7 Dec 2022

New Clinical Practice Guideline offers recommendations to manage hypoglycemia in people with diabetes

People with diabetes are benefiting from advances in medications and technologies to lower their risk of hypoglycemia, according to a Clinical Practice Guideline issued today by the Endocrine Society.

7 Dec 2022

Study allows people with type 2 diabetes to choose their own medication

A large-scale new study offers a new approach to treating type 2 diabetes - that puts patients in charge of their own medication. The Trimaster study is the first to allow people with type 2 diabetes to choose their own medication, after trying three different drugs in succession.

7 Dec 2022

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Patients with localized, hormone receptor-positive, HER2-low breast cancer treated with trastuzumab deruxtecan (T-DXd, Enhertu) in the neoadjuvant setting had an overall response rate of 75 percent in the absence of anastrozole and 63 percent in combination with anastrozole, according to results from the phase II TRIO-US B-12 TALENT trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

Study identifies characteristics linked with higher likelihood of post COVID-19 condition diagnosis

Many studies have described a variety of long-term effects of COVID-19, with symptoms including fatigue and malaise, breathing difficulties, and cognitive problems, often referred to as post COVID-19 condition or long COVID.

7 Dec 2022

What is the prevalence of pulmonary tissue injury among hospitalized COVID-19 patients?

Researchers identified risk factors for and the prevalence of persistent pulmonary tissue alterations among hospitalized coronavirus disease 2019 (COVID-19) patients.

7 Dec 2022

Study: People with higher levels of vitamin D in the brain have better cognitive function

An estimated 55 million people worldwide live with dementia, a number that's expected to rise as the global population ages.

7 Dec 2022

Genomic assay can help identify breast cancer patients who may benefit from ovarian suppression therapy

Among premenopausal women with hormone receptor (HR)-positive, early-stage breast cancer enrolled in the SOFT trial, those with a high score on a genomic assay called Breast Cancer Index (BCI) had increased risk of distant recurrence, and those with low BCI benefited more from the addition of ovarian suppression therapy to endocrine therapy after 12 years of follow-up, according to data presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

Air pollution-triggered immune surveillance deficits in the lungs increase the risk of respiratory diseases with aging

Researchers highlighted the significance of air quality in preserving immune health over the human lifespan, especially lung-related immunity, owing to the lungs' continuous exposure to the environment.

7 Dec 2022

Physical functions among Japanese children deteriorated after the onset of pandemic, study finds

A team of researchers from Nagoya University in central Japan investigated how restrictions on children's activities during the COVID-19 pandemic affected their life habits and their abilities to perform physical activities.

6 Dec 2022

BGI Genomics and the University of Pécs launch a joint laboratory in Hungary

On November 29, 2022, BGI Genomics and the University of Pécs (UP) agreed to launch a joint laboratory in Hungary.

6 Dec 2022

Researchers identify micronutrient supplementation to reduce cardiovascular risk

Healthy diets are rich in antioxidants like amino acids, omega-3 fatty acids and vitamin C, but exactly how beneficial these micronutrients are for cardiovascular health has long been controversial.

6 Dec 2022

New approach enables robust intestinal mini-organs to be grown more easily in the lab

Growing human body parts in the lab is a common trope of horror movies and sci-fi books. But growing miniature organ-like tissues in the lab is already within our reach.

6 Dec 2022

New project aims to address the vast data-related problems in cancer research

The National Cancer Institute has awarded $10.5 million to the Division of Biostatistics at the Department of Population and Public Health Sciences at the Keck School of Medicine of USC.

6 Dec 2022

Research extends the powerful tool of immunotherapy to autoimmune diseases

The cancer therapy known as CAR-T has revolutionized treatment of some blood cancers since it was introduced in 2017. The therapy uses genetically altered immune cells to home in on cancer cells and destroy them.

6 Dec 2022

New technology could increase scan speeds of three-dimensional MRIs

Nicholas Dwork, PhD, assistant professor in the Department of Biomedical Informatics at the University of Colorado School of Medicine, has filed a provisional patent for a technology that could increase scan speeds of three-dimensional magnetic resonance imaging (MRI).

6 Dec 2022

Discovery of three new brain tumor subtypes could help to identify novel, effective therapies

Research lead by RCSI University of Medicine and Health Sciences has discovered three new subtypes of brain tumor which could help to identify new and effective therapies.

6 Dec 2022

Medicine News and Research

T-DXd leads to longer overall survival in HER2-positive metastatic breast cancer patients than T-DM1

HIV transmission from mother to child can be stopped with modern antiviral drugs

Cancer immunotherapies can become more potent depending on the time of day

Wearable technology could improve doctors' ability to administer precise medication doses

New Clinical Practice Guideline offers recommendations to manage hypoglycemia in people with diabetes

Study allows people with type 2 diabetes to choose their own medication

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Study identifies characteristics linked with higher likelihood of post COVID-19 condition diagnosis

What is the prevalence of pulmonary tissue injury among hospitalized COVID-19 patients?

Study: People with higher levels of vitamin D in the brain have better cognitive function

Genomic assay can help identify breast cancer patients who may benefit from ovarian suppression therapy

Air pollution-triggered immune surveillance deficits in the lungs increase the risk of respiratory diseases with aging

Physical functions among Japanese children deteriorated after the onset of pandemic, study finds

BGI Genomics and the University of Pécs launch a joint laboratory in Hungary

Researchers identify micronutrient supplementation to reduce cardiovascular risk

New approach enables robust intestinal mini-organs to be grown more easily in the lab

New project aims to address the vast data-related problems in cancer research

Research extends the powerful tool of immunotherapy to autoimmune diseases

New technology could increase scan speeds of three-dimensional MRIs

Discovery of three new brain tumor subtypes could help to identify novel, effective therapies

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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