Kidney Disease News and Research

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Study offers clues to clinical diagnosis of nephronophthisis in adults

Nephronophthisis (NPH) is a kidney disease affecting mainly children. Now, for the first time, researchers at Tokyo Medical and Dental University have studied a number of adults with NPH and highlighted clinical, genetic and pathological characteristics that could help in confirming this challenging diagnosis.

23 Apr 2021

New study demonstrates the effectiveness of COVID-19 vaccine in specific sub-populations

Several weeks following the publication of the large real-world Covid-19 vaccine effectiveness study by the Clalit Research Institute in Collaboration with Harvard University in the New England Journal of Medicine (NEJM), additional results focusing on vaccine effectiveness in specific sub-populations have now been published.

23 Apr 2021

COVID-19 survivors have increased risk of death for at least six months

As the COVID-19 pandemic has progressed, it has become clear that many survivors -; even those who had mild cases -; continue to manage a variety of health problems long after the initial infection should have resolved.

23 Apr 2021

Drugs can help prevent progression of cardiac hypertrophy in hemodialysis patients

Patients with chronic kidney dysfunction frequently develop thickening of the heart muscle, so-called left ventricular hypertrophy. This is particularly pronounced in patients who are in the late stage of renal dysfunction, that is to say those requiring renal replacement therapy such as hemodialysis.

22 Apr 2021

Researchers aim to better understand clinical features associated with COVID-19 mortality

To better understand the COVID-19 clinical feaures associated with mortality, an interdisciplinary team of researchers has investigated important factors and their influence on a patient’s death.

22 Apr 2021

Anti-diabetic drug metformin inhibits disease progression in Alport syndrome mouse model

Researchers from Kumamoto University have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) by ameliorating pathological conditions like reduced kidney function, glomerular damage, inflammation and fibrosis.

15 Apr 2021

Series of reviews discuss key issues in chronic kidney disease and bone disorders

Metabolic bone disease is a common complication of chronic kidney disease (CKD) and involves a broad spectrum of disorders of mineral metabolism that result in both skeletal and extra-skeletal consequences.

15 Apr 2021

COVID-19 deadlier than cars for over 40s, study finds

The study, which appeared on the pre-print server medRxiv, presented mortality rates and case-fatality rates for COVID-19 compared with other historic leading causes of death in the United States.

15 Apr 2021

Early monoclonal antibody therapies beneficial for COVID-19, finds study

A team of scientists recently conducted a large-scale study at Northwell Health, New York, USA, to evaluate the efficacy of neutralizing monoclonal antibody (MAB) therapies in preventing disease progression among patients with mild to moderate COVID-19. The findings reveal that the timing of initiating MAB therapy is a crucial factor in determining its efficacy against COVID-19.

14 Apr 2021

Mouse model closely replicates human NAFLD

Human non-alcoholic fatty liver disease (NAFLD) is a little-understood condition that significantly increases the risk of inflammation, fibrosis and liver cancer and ultimately requires liver transplant.

13 Apr 2021

Chemical modification of RNA appears to play a critical role in inherited kidney disorder

A chemical modification of RNA that can be influenced by diet appears to play a key role in polycystic kidney disease, an inherited disorder that is the fourth leading cause of kidney failure in the U.S., UT Southwestern researchers report in a new study.

13 Apr 2021

Study uncovers molecular reason why fecal transplants effectively treat C. difficile infections

Experts have uncovered a new molecular reason why faecal transplants are highly effective in treating infections such as C. difficile (a nasty bacteria that can infect the bowel), which could lead to more targeted treatments for this and other similar diseases.

9 Apr 2021

Researchers reveal blood clot risk and anticoagulation benefits in discharged COVID-19 patients

In the largest study of its kind, Feinstein Institutes for Medical Research and Northwell COVID-19 Research Consortium researchers reveal blood clot risk and anticoagulation benefits in hospitalized coronavirus disease 2019 (COVID-19) patients who have been recently discharged from the hospital.

9 Apr 2021

Effective response to HIV and COVID-19 pandemics requires accelerated research

The COVID-19 pandemic is affecting people with or at risk for HIV both indirectly, by interfering with HIV treatment and prevention services, and directly, by threatening individual health.

9 Apr 2021

Surgery to correct congenital heart disease linked to increased risk of adult hypertension

In a medical records study covering thousands of children, a U.S.-Canadian team led by researchers at Johns Hopkins Medicine concludes that while surgery to correct congenital heart disease (CHD) within 10 years after birth may restore young hearts to healthy function, it also may be associated with an increased risk of hypertension -- high blood pressure -- within a few months or years after surgery.

8 Apr 2021

Hopkins Medicine endocrinologist publishes first clinical practice review on diabetes management

New medicines for people who have diabetes seem to pop up all the time. Drugs that help the body break down carbohydrates, drugs that increase excretion of glucose in the urine, drugs that help muscles respond to insulin and drugs that stimulate the pancreas to produce it -; the list of pharmaceutical options to treat diabetes gets longer and longer.

7 Apr 2021

USGS study finds high levels of arsenic and uranium in private well water across Connecticut

A new U.S. Geological Survey study provides an updated, statewide estimate of high levels of naturally occurring arsenic and uranium in private well water across Connecticut.

7 Apr 2021

Study shows cost-effectiveness of behavior modification intervention for CKD patients

With a prevalence of about one in 10 people worldwide, chronic kidney disease (CKD) is a global health problem.

6 Apr 2021

Montana sticks to its patchwork Covid vaccine rollout as eligibility expands

Montana's Covid-19 vaccine distribution is among the most efficient in the nation, but closer examination reveals a patchwork of systems among counties and tribal governments that will be put to the test as the state opens vaccine eligibility to all people 16 and older starting this month.

5 Apr 2021

Long-COVID-19 is a significant risk in recovered patients post-hospitalization

A new study, which appeared in the British Medical Journal, reports on a retrospective study to examine the incidence and risk factors for ‘long COVID-19’, the term used to describe the long-term effects of COVID-19 on affected individuals.

2 Apr 2021

Kidney Disease News and Research

Study offers clues to clinical diagnosis of nephronophthisis in adults

New study demonstrates the effectiveness of COVID-19 vaccine in specific sub-populations

COVID-19 survivors have increased risk of death for at least six months

Drugs can help prevent progression of cardiac hypertrophy in hemodialysis patients

Researchers aim to better understand clinical features associated with COVID-19 mortality

Anti-diabetic drug metformin inhibits disease progression in Alport syndrome mouse model

Series of reviews discuss key issues in chronic kidney disease and bone disorders

COVID-19 deadlier than cars for over 40s, study finds

Early monoclonal antibody therapies beneficial for COVID-19, finds study

Mouse model closely replicates human NAFLD

Chemical modification of RNA appears to play a critical role in inherited kidney disorder

Study uncovers molecular reason why fecal transplants effectively treat C. difficile infections

Researchers reveal blood clot risk and anticoagulation benefits in discharged COVID-19 patients

Effective response to HIV and COVID-19 pandemics requires accelerated research

Surgery to correct congenital heart disease linked to increased risk of adult hypertension

Hopkins Medicine endocrinologist publishes first clinical practice review on diabetes management

USGS study finds high levels of arsenic and uranium in private well water across Connecticut

Study shows cost-effectiveness of behavior modification intervention for CKD patients

Montana sticks to its patchwork Covid vaccine rollout as eligibility expands

Long-COVID-19 is a significant risk in recovered patients post-hospitalization

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