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Cat allergen immunotherapy works better and more quickly when combined with monoclonal antibody

An experimental approach to enhancing a standard cat allergy treatment made it more effective and faster acting, and the benefits persisted for a year after treatment ended, a study supported by the National Institutes of Health has found.

11 Oct 2022

Oxford researchers report findings from Phase 1 clinical trial of intranasal COVID-19 vaccine

Researchers from the University of Oxford have today reported new findings from a Phase 1 clinical trial studying the safety and immune response of an intranasally-administered vaccine against COVID-19.

11 Oct 2022

If you’re worried about the environment, consider being composted when you die

Would you rather be buried or cremated when you die? If you feel the way I do, the answer is neither. I cringe at the thought of my body burning up at well over 1,000 degrees Fahrenheit or being pumped full of toxic chemicals and spending the rest of eternity in a cramped box 6 feet underground.

11 Oct 2022

Hospitals have been slow to bring on addiction specialists

In December, Marie, who lives in coastal Swampscott, Massachusetts, began having trouble breathing. Three days after Christmas, she woke up gasping for air and dialed 911.

11 Oct 2022

Scientists discover a promising strategy for development of broad-spectrum antiviral therapies

Researchers have identified a promising strategy for development of broad-spectrum antiviral therapies that centers around promoting a strong immune response capable of stopping a number of viruses in their infectious tracks.

10 Oct 2022

New class of drugs can safely counter allergic asthma without creating vulnerability to infections

Blocking the action of calcium signals in immune cells suppresses the most common form of asthma, but without compromising the body's defenses against flu viruses, a new study finds.

7 Oct 2022

Researchers investigate lung disease seen in previously deployed military personnel

Military personnel who were deployed in Afghanistan and Iraq may have been exposed to significant amounts of dust and other respiratory hazards, leading to persistent respiratory symptoms and diseases like asthma and bronchiolitis.

7 Oct 2022

UMSOM researchers identify how multiple genes of SARS-CoV-2 affect disease severity

University of Maryland School of Medicine researchers have identified how multiple genes of SARS-CoV-2 affect disease severity, which could lead to new ways in how we develop future vaccines or develop newer treatments.

7 Oct 2022

Study evaluates efficacy of a candidate SARS-CoV-2 subunit vaccine to protect endangered black-footed-ferrets

In a new study, researchers assessed the safety, efficacy, and immunogenicity of a candidate SARS-CoV-2 subunit vaccine in black-footed ferrets (BFF), and investigated the susceptibility of these endangered North American mammals to the virus.

7 Oct 2022

COVID‐19 pathology across different tissues

Researchers investigated COVID-19 pathophysiology in multiple tissues, including the lungs, kidneys, heart, and brain, for a deeper understanding of its acute and long‐term symptoms.

7 Oct 2022

New platform for gene editing may change the landscape of CRISPR-based therapeutics

A team of researchers at Northwestern University has devised a new platform for gene editing that could inform the future application of a near-limitless library of CRISPR-based therapeutics.

7 Oct 2022

Clinical trials of novel COVID-19 vaccine developed in Brazil to begin soon

Testing on humans of a novel COVID-19 vaccine developed in Brazil will begin this year. It performed well in animal trials, as reported in an article published in August in Nature Communications.

6 Oct 2022

Intranasal vaccine represents an effective broad-spectrum COVID-19 vaccine strategy

Researchers evaluated the efficacy of dNS1-RBD, a novel intranasal COVID-19 vaccine.

6 Oct 2022

Detecting microplastics in human samples

A new study discusses how microplastics exposure to humans can be examined, preventative measures, and future possibilities in microplastics research.

6 Oct 2022

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Researchers engineered biparatopic nanobodies against SARS-CoV-2.

5 Oct 2022

Particle radioactivity enhances PM2.5 toxicity and increases risk of cardiovascular disease mortality

Particle radioactivity, a characteristic of air pollution that reflects the colorless, odorless gas radon found in fine particulate matter (PM2.5) air pollution, enhances PM2.5 toxicity and increases risk of death from cardiovascular disease, especially from heart attack or stroke, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

5 Oct 2022

Multi-organ chip directly measures the biological impact of nanoparticles

What happens when we breathe in nanoparticles emitted by a laser printer, for example? Could these nanoparticles damage the respiratory tract or perhaps even other organs? To answer these questions, Fraunhofer researchers are developing the "NanoCube" exposure device.

5 Oct 2022

Viagra and Cialis may not be suitable candidates for treating dementia, NIH DREAM study shows

Results from the National Institutes of Health's Drug Repurposing for Effective Alzheimer's Medicines (DREAM) study show that sildenafil (Viagra) and tadalafil (Cialis) may not be suitable candidates for treating dementia.

4 Oct 2022

Early-stage clinical trial evaluating bacteriophage therapy in adults with cystic fibrosis begins

Enrollment has begun in an early-stage clinical trial evaluating bacteriophage therapy in adults with cystic fibrosis (CF) who carry Pseudomonas aeruginosa (P. aeruginosa) in their lungs.

4 Oct 2022

Multiomic comparison shows a reduction in circulating monocytes correlated with persistent post-COVID-19 pulmonary fibrosis

In a new study, researchers identified distinguishing immune features of coronavirus disease 2019 (COVID-19) in patients with late-resolving pulmonary fibrosis (LR COVID-PF) and early-resolving (ER COVID-PF).

4 Oct 2022

Lungs News and Research

Cat allergen immunotherapy works better and more quickly when combined with monoclonal antibody

Oxford researchers report findings from Phase 1 clinical trial of intranasal COVID-19 vaccine

If you’re worried about the environment, consider being composted when you die

Hospitals have been slow to bring on addiction specialists

Scientists discover a promising strategy for development of broad-spectrum antiviral therapies

New class of drugs can safely counter allergic asthma without creating vulnerability to infections

Researchers investigate lung disease seen in previously deployed military personnel

UMSOM researchers identify how multiple genes of SARS-CoV-2 affect disease severity

Study evaluates efficacy of a candidate SARS-CoV-2 subunit vaccine to protect endangered black-footed-ferrets

COVID‐19 pathology across different tissues

New platform for gene editing may change the landscape of CRISPR-based therapeutics

Clinical trials of novel COVID-19 vaccine developed in Brazil to begin soon

Intranasal vaccine represents an effective broad-spectrum COVID-19 vaccine strategy

Detecting microplastics in human samples

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Particle radioactivity enhances PM2.5 toxicity and increases risk of cardiovascular disease mortality

Multi-organ chip directly measures the biological impact of nanoparticles

Viagra and Cialis may not be suitable candidates for treating dementia, NIH DREAM study shows

Early-stage clinical trial evaluating bacteriophage therapy in adults with cystic fibrosis begins

Multiomic comparison shows a reduction in circulating monocytes correlated with persistent post-COVID-19 pulmonary fibrosis

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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