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Scientists discover how MEK inhibitor boosts antitumor activity and slows cancer progression

Understanding the effects of certain targeted therapies on antitumor immunity is necessary to design combined interventions for more effective cancer treatment.

1 Nov 2016

Carotenoid pigment compound reduces invasiveness of tumors in mouse models of lung cancer

Beta-cryptoxanthin (BCX), a carotenoid pigment compound found primarily in plants, reduces the number and invasiveness of tumors in mouse and cell models of lung cancer, report scientists from the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University.

1 Nov 2016

Penn study reveals new sights into how some intestinal cells can withstand chemotherapy and radiation

When treating cancer with chemotherapy and radiation, decisions about dose must walk a fine line between attacking cancerous cells and preserving healthy ones.

31 Oct 2016

Research findings may lead to new treatment option for ovarian cancer

A new study has identified an effective combination therapy for treating ovarian cancer cells.

31 Oct 2016

Natural compound slows typical signs of aging in mice

Much of human health hinges on how well the body manufactures and uses energy. For reasons that remain unclear, cells' ability to produce energy declines with age, prompting scientists to suspect that the steady loss of efficiency in the body's energy supply chain is a key driver of the aging process.

27 Oct 2016

Supercomputer simulations of p53 protein could boost future anti-cancer drug discovery

Even though it's almost impossible to see, computational biophysicist Rommie Amaro is using the Stampede supercomputer at the Texas Advanced Computing Center at The University of Texas at Austin to model the largest atomic level system of the tumor suppression protein p53 to date -- over 1.5 million atoms.

27 Oct 2016

Non-toxic Salmonella strain could be promising new treatment option for cancer

According to the Centers for Disease Control, 48 million Americans contract foodborne diseases annually, with Salmonella being the leading cause of illness.

27 Oct 2016

Biovica, Eisai sign agreement to analyze DiviTum for improved cancer drug assessment in animal models

Biovica and Eisai Inc. have entered into a lab services agreement to analyze DiviTum, an assay measuring serum thymidine kinase, for improved drug evaluation in animal cancer models.

27 Oct 2016

Researchers identify existing drugs that appear to prevent aggressive subtype of pediatric brain tumors

More than 4,000 children and teens are diagnosed with brain cancer each year and the disease kills more children than any other cancer.

27 Oct 2016

Research shows potential way to counteract glioblastoma growth by blocking PPARα receptor

One of the most remarkable features of glioblastoma is the metabolic reprogramming of cancerous cells, resulting in uncontrolled cell proliferation, hypoxic conditions and angiogenesis.

27 Oct 2016

Researchers receive grant to investigate how gut microbiome influences breast cancer

Researchers from the University of Illinois at Chicago and the University of Chicago have received a three-year, $900,000 Defense Department grant to investigate how the gut microbiome – the trillions of bacteria, viruses and other bugs that make our digestive systems their home – influences breast cancer.

26 Oct 2016

Researchers find link between estrogen levels in lung tissue and SMLA in postmenopausal women

Thanks to advances in medical imaging, the detection rate for synchronous multiple lung adenocarcinoma (SMLA) has been on the rise. Cases of SMLA in Japanese women have been on the rise despite having a national smoking rate of less than 10% in recent years.

26 Oct 2016

WSU researchers identify potential new diagnostic tool for early detection of colorectal cancer

Scientists at Washington State University and Johns Hopkins Medical School have discovered a fast, noninvasive method that could lead to the early diagnosis of colorectal cancer.

25 Oct 2016

IU scientists find evidence for link between prostate cancer and Ewing's sarcoma

Medical researchers at Indiana University Bloomington have found evidence for a link between prostate cancer, which affects millions of men age 50 and older, and Ewing's sarcoma, a rare form of cancer that affects children and young adults.

25 Oct 2016

Immunotherapy drug approved by FDA as first-line treatment for non-small cell lung cancer

Pembrolizumab, an immunotherapy drug that was extensively evaluated by UCLA cancer researcher Dr. Edward Garon, has been approved by the U.S. Food & Drug Administration as first-line treatment for non-small cell lung cancer (NSCLC).

25 Oct 2016

Breakthrough Award supports research on role of chronic stress in breast cancer development

Rutgers Cancer Institute of New Jersey resident research member Wenwei Hu, PhD, has received a $596,250 Breakthrough Award from the U.S. Department of Defense through its Breast Cancer Research Program to study the role of chronic stress in breast cancer development.

25 Oct 2016

New approach could overcome large immunosuppressive tumors

Harnessing the body's own immune system to destroy tumors is a tantalizing prospect that has yet to realize its full potential. However, a new advance from MIT may bring this strategy, known as cancer immunotherapy, closer to becoming reality.

24 Oct 2016

Screening for prolactin receptor could help improve TNBC prognosis and treatment

A study conducted at the Research Institute of the McGill University Health Centre suggests screening breast cancer patients for the prolactin receptor could improve the prognosis for patient and may help them avoid unnecessary and invasive treatments

24 Oct 2016

Identification of new lung cancer subtypes could lead to personalized immunotherapies

Personalized therapies can potentially improve the outcomes of patients with lung cancer, but how to best design such an approach is not always clear.

24 Oct 2016

Basal tumor cell marker could help physicians personalize care for patients with bladder cancer

Tumor cells collected during the removal of a cancerous bladder and - in some cases - transplanted into mice with weakened immune systems, could help physicians rapidly identify high-risk cancers, determine prognosis and refine the use of biomarkers to personalize care for patients with this common cancer, according to a study published online on Oct. 24, 2016, in Scientific Reports.

24 Oct 2016

Tumor News and Research

Scientists discover how MEK inhibitor boosts antitumor activity and slows cancer progression

Carotenoid pigment compound reduces invasiveness of tumors in mouse models of lung cancer

Penn study reveals new sights into how some intestinal cells can withstand chemotherapy and radiation

Research findings may lead to new treatment option for ovarian cancer

Natural compound slows typical signs of aging in mice

Supercomputer simulations of p53 protein could boost future anti-cancer drug discovery

Non-toxic Salmonella strain could be promising new treatment option for cancer

Biovica, Eisai sign agreement to analyze DiviTum for improved cancer drug assessment in animal models

Researchers identify existing drugs that appear to prevent aggressive subtype of pediatric brain tumors

Research shows potential way to counteract glioblastoma growth by blocking PPARα receptor

Researchers receive grant to investigate how gut microbiome influences breast cancer

Researchers find link between estrogen levels in lung tissue and SMLA in postmenopausal women

WSU researchers identify potential new diagnostic tool for early detection of colorectal cancer

IU scientists find evidence for link between prostate cancer and Ewing's sarcoma

Immunotherapy drug approved by FDA as first-line treatment for non-small cell lung cancer

Breakthrough Award supports research on role of chronic stress in breast cancer development

New approach could overcome large immunosuppressive tumors

Screening for prolactin receptor could help improve TNBC prognosis and treatment

Identification of new lung cancer subtypes could lead to personalized immunotherapies

Basal tumor cell marker could help physicians personalize care for patients with bladder cancer

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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