Laboratory News and Research

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Fragrances can enhance learning during sleep, shows new study

Effortless learning during sleep is the dream of many people. The supportive effect of smells on learning success when presented both during learning and sleep was first proven in an extensive sleep laboratory study.

31 Jan 2020

Jackson Laboratory announces research affiliation, publishes new papers on genes and microbiome

January has been an exciting month at The Jackson Laboratory (JAX). With this surplus of news, we wanted to share three major stories from the past week:

31 Jan 2020

Scientists describe genetic program behind primordial lung progenitors

For the first time, researchers describe the genetic program behind primordial lung progenitors--embryonic cells that give rise to all the cells that form the lining of the respiratory system after birth.

31 Jan 2020

New combination treatment could help fight advanced melanoma

A study by researchers at the UCLA Jonsson Comprehensive Cancer Center suggests that using an immunotherapy drug called NKTR-214, also known as bempegaldesleukin, in combination with an infusion of anti-tumor immune cells, or T cells, may produce a stronger immune response that could help fight advanced melanoma.

31 Jan 2020

Choice of anesthesia may change metastatic process of breast cancer

A new study led by Stony Brook University Cancer Center researchers to be published in Nature Communications suggests that the choice of anesthesia may change the metastatic process of breast cancer by affecting the cytokine and microenvironment.

31 Jan 2020

Modified form of poliovirus shows potential as cancer vaccine in animal studies

A modified form of poliovirus, pioneered at Duke Cancer Institute as a therapy for glioblastoma brain tumors, appears in laboratory studies to also have applicability for pediatric brain tumors when used as part of a cancer vaccine.

31 Jan 2020

Scientists track down a potential target for new sleeping sickness drugs

Using ultra-bright X-ray flashes, a team of researchers has tracked down a potential target for new drugs against sleeping sickness: The scientists have decoded the detailed spatial structure of a vital enzyme of the pathogen, the parasite Trypanosoma brucei.

30 Jan 2020

Study assesses quality of life among adults in India with mild-to-moderate CKD

A new study indicates that even early stages of chronic kidney disease (CKD) can negatively impact individuals' quality of life.

30 Jan 2020

Research uncovers how HIV develops resistance to key drugs

The mechanism behind how HIV can develop resistance to a widely-prescribed group of drugs has been uncovered by new research from the Crick and Dana-Farber Cancer Institute, with the findings opening the door to the development of more effective treatments.

30 Jan 2020

WPI researcher awarded grant for research into leading cause of aortic valve dysfunction

Worcester Polytechnic Institute researcher Kristen Billiar has been awarded a $154,000 grant from the American Heart Association to determine how cell death leads to calcium deposits in heart tissue that cause aortic valves to fail.

30 Jan 2020

First in-depth analysis of primate ovarian aging at single-cell resolution

Due to the modern tendency to postpone childbirth until later in life, a growing number of women are experiencing issues with infertility.

30 Jan 2020

Researchers use new technique to improve the ability to model lung diseases

Using a combination of pluripotent stem cells (cells that can potentially produce any cell or tissue type) and machine learning (artificial intelligence that allows computers to learn automatically), researchers have improved how they generate lung cells.

30 Jan 2020

Advances in tuberculosis research yield immune responses

A new study published in January 2020 in the journal Science Translational Medicine depicts for the first time ever a beautifully detailed map of the way three different species reacts to tuberculosis, based on their genetic and immune differences.

30 Jan 2020

Turning stink into therapy for atherosclerosis

In an amusing but amazing turnaround, it seems the most foul-smelling compound on earth, called putrescine, could help relieve chronic inflammation, most importantly in the arterial thickening called atherosclerosis. This discovery is reported in the journal Cell Metabolism in January 2020.

30 Jan 2020

Gene-editing taken to advanced levels in human stem cells

A new study published in the journal Stem Cell Reports in January 2020 reports the use of an adaptation to a commonly used gene editing technology to achieve a more than 900% increase in efficiency.

30 Jan 2020

Scientists reveal clinical features of Wuhan coronavirus patients

The Wuhan coronavirus, or the 2019-nCoV, which originated in Wuhan City in Hubei province infected more than 7,700 people with the death toll topping more than 170. China reports 38 deaths in just 24 hours, making the outbreak one of the deadliest ones the country has faced.

30 Jan 2020

Wuhan coronavirus is genetically different from human SARS, MERS-CoV, study found

The Wuhan coronavirus or the 2019-nCoV or novel coronavirus is a new human-infecting coronavirus genetically different from human SARS (Severe Acute Respiratory Syndrome), and MERS-CoV (Middle East Respiratory Syndrome), a team of scientists has found.

30 Jan 2020