Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Insilico Medicine to showcase results of generative biology target ID system

Insilico Medicine, a biotechnology company developing end-to-end drug discovery pipelines utilizing the next-generation artificial intelligence, to present new results of its generative biology pipeline resulting in novel targets in liver disease.

12 Jan 2020

Researchers identify molecular regulator that can help treat obesity

Fat cells are filled with droplets coated by molecules that act like hotel doormen: These "doormen" control cellular access for nutrients as well as for the exit of energy-supplying molecules called lipids.

10 Jan 2020

Number of alcohol-related deaths has doubled in the U.S., shows study

An analysis of death certificates suggests that the number of alcohol-related deaths doubled in the United States between 1999-2017.

8 Jan 2020

ACG publishes new guideline on disorders of hepatic and mesenteric circulation

The American College of Gastroenterology is pleased to announce the publication of a new ACG Clinical Guideline on Disorders of Hepatic and Mesenteric Circulation, which was published online today in The American Journal of Gastroenterology.

7 Jan 2020

Longevity protein SIRT6 also plays crucial role in burning and regulating liver fat metabolism

Fatty liver, or hepatic steatosis, which develops when the body produces too much fat or doesn't metabolize fat efficiently enough, affects around 25% of the global population. Excess fat is stored in liver cells, where it accumulates and can cause fatty liver and other diseases.

22 Dec 2019

Edematous severe acute malnutrition linked to DNA modification

A group led by researchers at Baylor College of Medicine has identified significant differences at the epigenetic level - the chemical tags in DNA that help regulate gene expression - between two clinically distinct forms of acute childhood malnutrition known as edematous severe acute malnutrition (ESAM) and non-edematous SAM (NESAM).

19 Dec 2019

Heavy drinking damages the heart

Drinking too much destroys the liver, as is well known. A new study published in the Journal of the American Heart Association on December 18, 2019, shows that excessive alcohol consumption also damages the heart muscle. This is seen by a rise in the level of certain biological molecules in the blood.

18 Dec 2019

Using math equations to detect and forecast liver cancer risk

The use of mathematical modeling in the study of biological systems has become a challenging and rewarding field of research as it yields many unknown pieces of information. A new study published online on December 16, 2019, in the journal Proceedings of the National Academy of Science (PNAS).

17 Dec 2019

Women who live near green space may be at lower risk of excess weight, obesity

Women who live less than 300 meters from green space may be at lower risk of excess weight or obesity.

17 Dec 2019

Perinatal exposure of rats to flame retardants changes the liver epigenome

Studies have shown that perinatal exposure of rats and mice to common flame retardants found in household items permanently reprograms liver metabolism, often leading later in life to insulin resistance and non-alcoholic fatty liver disease.

13 Dec 2019

Efforts to prevent new HIV transmissions must also focus on people already living with HIV

Efforts to prevent new HIV transmissions in the United States must be accompanied by advances in addressing HIV-associated comorbidities to improve the health of people already living with HIV, National Institutes of Health experts assert in the third of a series of JAMA commentaries.

11 Dec 2019

New research may help guide future treatment for non-alcoholic fatty liver disease

Edith Cowan University researchers have found that a chronic disease affecting up to 80 per cent of overweight people may be causing an iron deficiency that simply leaves them too tired to get off the couch.

11 Dec 2019

Study explores cost-effectiveness of transient elastography for detecting liver fibrosis

Non-alcoholic fatty liver diseases (NAFLD) and alcohol-related diseases (ALD) are currently the leading cause of chronic disease, cancer and mortality associated with this organ in developed countries.

10 Dec 2019

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

Researchers demonstrated that Lactobacillus rhamnosus can dose-dependently reestablish a balanced intestinal microbiome and counter the liver-damaging effects of alcohol consumption in mice to reverse the results of chronic alcohol-induced liver injury.

9 Dec 2019

New startup aims to prevent reperfusion-related organ damage after liver transplant

Roughly 65 years ago, the first human organ transplant was successfully performed. A decade later, heart and liver transplants became possible. Now, a startup founded by researchers from the Medical University of South Carolina and elsewhere hopes to bring about the next major breakthrough.

8 Dec 2019

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

Patients with nonalcoholic steatohepatitis, a chronic liver disease and a leading cause for liver transplantation in the U.S., currently lack an approved drug therapy, but this may soon change.

6 Dec 2019

Chronic disease prevention could help curb the opioid epidemic

Preventing chronic disease could help curb the opioid epidemic, according to research from the University of Georgia.

5 Dec 2019

Early diagnosis and treatment of chronic inflammation may reduce illness, save lives

Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.

5 Dec 2019

Georgia State professor selected as National Academy of Inventors Fellow

Jenny Yang, a Regents' Professor of chemistry at Georgia State University and the associate director of the Center for Diagnostics and Therapeutics, has been selected as a National Academy of Inventors (NAI) Fellow, the academy board announced on Tuesday.

5 Dec 2019

Researchers create 3D liver model for improved diagnosis of non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and distinguishing different stages of the disease. However, this technique provides only two-dimensional images of the liver tissue in low resolution and overlooks potentially important 3D structural changes.

4 Dec 2019

Liver Disease News and Research

Further Reading

Insilico Medicine to showcase results of generative biology target ID system

Researchers identify molecular regulator that can help treat obesity

Number of alcohol-related deaths has doubled in the U.S., shows study

ACG publishes new guideline on disorders of hepatic and mesenteric circulation

Longevity protein SIRT6 also plays crucial role in burning and regulating liver fat metabolism

Edematous severe acute malnutrition linked to DNA modification

Heavy drinking damages the heart

Using math equations to detect and forecast liver cancer risk

Women who live near green space may be at lower risk of excess weight, obesity

Perinatal exposure of rats to flame retardants changes the liver epigenome

Efforts to prevent new HIV transmissions must also focus on people already living with HIV

New research may help guide future treatment for non-alcoholic fatty liver disease

Study explores cost-effectiveness of transient elastography for detecting liver fibrosis

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

New startup aims to prevent reperfusion-related organ damage after liver transplant

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

Chronic disease prevention could help curb the opioid epidemic

Early diagnosis and treatment of chronic inflammation may reduce illness, save lives

Georgia State professor selected as National Academy of Inventors Fellow

Researchers create 3D liver model for improved diagnosis of non-alcoholic fatty liver disease

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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