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Study uncovers new drug-gene mutation combinations that can kill cancer cells

In an effort to expand the number of cancer gene mutations that can be specifically targeted with personalized therapies, researchers at University of California San Diego School of Medicine and Moores Cancer Center looked for combinations of mutated genes and drugs that together kill cancer cells.

22 Jul 2016

Researchers unveil engineered protein to suppress cancer-promoting message within cells

Over a century of research has shined light on the once-murky innards of our cells, from the genes that serve as our "blueprints" to the proteins and other molecules that are our cellular taskmasters.

22 Jul 2016

ASH commits $3 million annual funding to help sustain promising blood disease research

With a $3 million annual commitment to support promising blood disease research amid limited National Institutes of Health funding, the American Society of Hematology--the world's largest professional society concerned with the causes and treatment of blood disorders--today announced the formal establishment of the ASH Bridge Grant program after an extended four-year pilot study.

22 Jul 2016

Researchers identify important therapeutic target for small cell lung cancer

UT Southwestern Medical Center researchers have identified a protein termed ASCL1 that is essential to the development of small cell lung cancer and that, when deleted in the lungs of mice, prevents the cancer from forming.

22 Jul 2016

ASTRO clinical practice statement outlines recommendations to customize treatment for rectal cancer

The American Society for Radiation Oncology recently issued a new clinical practice statement, "Appropriate Customization of Radiation Therapy for Stage II and III Rectal Cancer: An ASTRO Clinical Practice Statement Using the RAND/UCLA Appropriateness Method."

21 Jul 2016

New imaging tool may help detect presence of androgen receptor in prostate cancer patients

Prostate cancer is one of the most common cancers in men. Tumor growth is critically regulated by the androgen receptor, and treatment strategies to lower androgens, such as testosterone, are a mainstay of clinical treatment.

21 Jul 2016

New study offers hypothesis why obese patients fare worse during cancer treatment

Across many cancer types, obese patients fare worse than leaner patients. Now a University of Colorado Cancer Center study published in the journal Cell Stem Cell offers a compelling hypothesis why: researchers found that leukemia stem cells "hide" in fatty tissue, even transforming this tissue in ways that support their survival when challenged with chemotherapy. It is as if leukemia stem cells not only use fatty tissue as a robbers' cave to hide from therapy, but actively adapt this cave to their liking.

21 Jul 2016

Scientists find promising new method to detect and treat recurrence of ovarian cancer

Researchers at the Mayo Clinic Center for Individualized Medicine have found a promising new way to monitor and treat recurrence of ovarian cancer -- a hard-to-detect disease that claims many lives.

21 Jul 2016

Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

A new scientific study has identified why colorectal cancer cells depend on a specific nutrient, and a way to starve them of it. Over one million men and women are living with colorectal cancer in the United States.

21 Jul 2016

Adding new monoclonal antibody to chemotherapy improves survival in soft-tissue sarcoma patients

Adding a novel monoclonal antibody therapy to traditional chemotherapy increased median survival by nearly a year in patients with advanced sarcoma, a lethal soft-tissue cancer.

21 Jul 2016

Study reports BV therapy may be curative in some Hodgkin lymphoma patients

Five-year survival data published online today in Blood, the Journal of the American Society of Hematology, suggest that the targeted therapy brentuximab vedotin may have cured some Hodgkin lymphoma patients whose disease has persisted despite receiving previous therapies.

19 Jul 2016

Scientists capture atomic level snapshots of how key enzyme modifies signaling proteins

Scientists have captured atomic level snapshots showing how one key enzyme modifies a protein involved in turning genes on or off inside cells. Understanding this process-which is particularly important when cells are first taking on specialized identities such as nerve cells, muscle, skin, and so on-helps explain how complex organisms can arise from a finite number of genes.

19 Jul 2016

Study finds new data about dMMR's hereditary basis in rectal cancer

Up to 15 percent of colorectal cancers show a genetic mutation known as DNA mismatch repair deficiency, or dMMR.

19 Jul 2016

New mathematical model can help predict breast cancer growth, occurrence of metastases

Personalized medicine is a healthcare approach in which medical procedures are tailored to the individual patient's genetic, physiological, and biochemical type along with other characteristics. Cancer treatment is one type of care where a personalized approach is most needed and often applied.

18 Jul 2016

New method helps characterize immune cells in tumor tissues

Despite recent achievements in the development of cancer immunotherapies, only a small group of patients typically respond to them. Predictive markers of disease course and response to immunotherapy are urgently needed.

18 Jul 2016

Scientists capture new images of calcium-shuttling molecule linked to aggressive cancers

Scientists have captured new images of a calcium-shuttling molecule that has been linked to aggressive cancers. The three-dimensional structure could help researchers develop novel therapies and diagnostic tools for diseases that are caused by a malfunction in calcium adsorption.

18 Jul 2016

Cancer immunotherapy could treat HIV

A type of immunotherapy that has shown promising results against cancer could also be used against HIV, the virus that causes AIDS.

17 Jul 2016

Researchers propose new approach to target chemotherapy medications specifically to sarcomas

Sarcoma is an aggressive form of cancer responsible for up to 20 percent of childhood cancers. Tumors often first appear in the extremities and the abdomen. Surgery is a primary treatment, but it often is combined with chemotherapy.

15 Jul 2016

New study highlights role of TANs in regulating T cell responses in patients with early-stage lung cancer

The microenvironment of tumors is a mix of cell types, mostly comprised of inflammatory cells. White blood cells, recruited from the blood and bone marrow, represent a significant portion of these inflammatory cells and influence nearly all steps of tumor progression.

15 Jul 2016

Researchers trace lineage of sarcoma back to pericyte

Scientists at Duke Health are part of a team that has discovered a type of cell surrounding blood vessels can also serve as a starting point for sarcoma, a form of cancer that occurs in bones and connective tissues.

14 Jul 2016

Tumor News and Research

Study uncovers new drug-gene mutation combinations that can kill cancer cells

Researchers unveil engineered protein to suppress cancer-promoting message within cells

ASH commits $3 million annual funding to help sustain promising blood disease research

Researchers identify important therapeutic target for small cell lung cancer

ASTRO clinical practice statement outlines recommendations to customize treatment for rectal cancer

New imaging tool may help detect presence of androgen receptor in prostate cancer patients

New study offers hypothesis why obese patients fare worse during cancer treatment

Scientists find promising new method to detect and treat recurrence of ovarian cancer

Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

Adding new monoclonal antibody to chemotherapy improves survival in soft-tissue sarcoma patients

Study reports BV therapy may be curative in some Hodgkin lymphoma patients

Scientists capture atomic level snapshots of how key enzyme modifies signaling proteins

Study finds new data about dMMR's hereditary basis in rectal cancer

New mathematical model can help predict breast cancer growth, occurrence of metastases

New method helps characterize immune cells in tumor tissues

Scientists capture new images of calcium-shuttling molecule linked to aggressive cancers

Cancer immunotherapy could treat HIV

Researchers propose new approach to target chemotherapy medications specifically to sarcomas

New study highlights role of TANs in regulating T cell responses in patients with early-stage lung cancer

Researchers trace lineage of sarcoma back to pericyte

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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