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U-M receives $20 million gift to support research and development of life-saving therapies

The University of Michigan has received a $20 million gift from the Maxine and Stuart Frankel Foundation of Bloomfield Hills, Michigan, to support the research and development of life-saving therapies at Michigan Medicine in collaboration with other institutions.

18 Dec 2019

Moffitt researchers develop efficient method for creating mouse models to study melanoma

Genetically engineered mouse models are often used by scientists to study how the addition, deletion or mutation of genes affects the development of disease and effects of drugs.

17 Dec 2019

Leukemia patients treated with common cancer drug have heightened risk of heart failure

Patients with acute lymphoblastic leukemia or acute myeloid leukemia who are treated with anthracyclines are at a heightened risk of heart failure- most often within one year of exposure to the chemotherapy treatment, according to a new study led by researchers at Penn Medicine.

17 Dec 2019

Researchers identify novel genetic signature with prognostic value for certain breast cancers

Researchers have identified a genetic signature with prognostic value for certain kinds of breast cancer. The discovery also contributes to a better understanding of the molecular mechanisms of pathological angiogenesis, the aberrant proliferation of blood vessels that occurs during cancer and other diseases.

17 Dec 2019

Brazilian researchers create hepatic organoids by 3D bioprinting

Using human blood cells, Brazilian researchers have succeeded in obtaining hepatic organoids ("mini-livers") that perform all of the liver's typical functions, such as producing vital proteins, storing vitamins, and secreting bile, among many others.

17 Dec 2019

Scientists reveal brain mechanisms and functional regions that underlie confirmation bias

An international research team comprising neuroscientists at Virginia Tech, University College London and the University of London revealed brain mechanisms and functional regions that underlie confirmation bias -- a phenomenon where people strongly favor information that reinforces their existing opinions over contradictory ones.

17 Dec 2019

Study finds new drivers of destructive inflammation

Scientists describe in Nature Immunology an entirely new molecular process in mice that triggers T cell-driven inflammation and causes different auto-immune diseases.

17 Dec 2019

Combination of two antibiotics eradicates latent tuberculosis in macaques

A major goal of tuberculosis (TB) research is to find a way to treat people with the latent (or inactive) form of the disease to keep them from developing symptomatic TB.

17 Dec 2019

Study shows the effect of obesity on routine blood tests in children

Weight may affect doctors' ability to correctly interpret routine blood tests in children, according to new research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

17 Dec 2019

Smart, nature-inspired system provides continuous information on patient’s health

Researchers at the Technion-Israel Institute of Technology and China's Xidian University present, in Chemical Reviews, a comprehensive review of smart systems that provide continuous information on a subject's health.

17 Dec 2019

Antioxidant in green tea plant could be key to fighting tuberculosis

An antioxidant found in the green tea plant could become key to tackling tuberculosis one day, a team of international scientists led by Nanyang Technological University, Singapore has found.

17 Dec 2019

Stroke drug improves stem cell therapy in rat spinal cord injury models

Four months after treating them, Yasuhiro Shiga, MD, PhD, checked on his rats. Walking into the lab, he carried minimal expectations.

17 Dec 2019

ELRIG UK and British Pharmacological Society form strategic alliance to improve education, drive drug discovery

The European Laboratory Research & Innovation Group UK and the British Pharmacological Society, announced today that they have formed a strategic alliance.

17 Dec 2019

Study shows nilotinib drug is safe and well tolerated in patients with Parkinson's disease

A clinical trial investigating the repurposed cancer drug nilotinib in people with Parkinson's disease finds that it is reasonably safe and well tolerated.

17 Dec 2019

Simple, new test can detect dangerous levels of fluoride in drinking water

Northwestern University synthetic biologists developed a simple, inexpensive new test that can detect dangerous levels of fluoride in drinking water.

16 Dec 2019

Tackling antibiotic resistance head-on with CRISPR

With modern advances in genetic engineering occurring almost every day, the latest discovery concerns antibiotic resistance. Using the powerful gene editor CRISPR, scientists reported the development of a gene-drive system that is 100 times as efficient as other current systems at inactivating a specific bacterial gene responsible for making the bacterium antibiotic-resistant and which is present as multiple copies within the same bacterial cell.

16 Dec 2019

Higher temperatures and increased rainfall could make RSV epidemics less severe, more common

One of the first studies to examine the effect of climate change on diseases such as influenza that are transmitted directly from person to person has found that higher temperatures and increased rainfall could make outbreaks less severe but more common, particularly in North America.

16 Dec 2019

Evolutionarily novel genes found to be expressed in tumors

A team of scientists from Peter the Great St.Petersburg Polytechnic University (SPbPU) studied the evolutionary ages of human genes and identified a new class of them expressed in tumors -- tumor specifically expressed, evolutionarily novel (TSEEN) genes.

16 Dec 2019

Study suggests link between bacteria in the upper airway and asthma severity

A new study led by Washington University School of Medicine in St. Louis suggests there is a link between bacteria that live in the upper airway and the severity of asthma symptoms among children with mild to moderate asthma.

16 Dec 2019

The evidence for BRCA1/2 or any genetic testing in breast cancer patients

A new statement by the American College of Medical Genetics and Genomics (ACMG), published in the journal Genetics in Medicine, discusses the place of germline genetic testing in breast cancer patients.

15 Dec 2019

Laboratory News and Research

U-M receives $20 million gift to support research and development of life-saving therapies

Moffitt researchers develop efficient method for creating mouse models to study melanoma

Leukemia patients treated with common cancer drug have heightened risk of heart failure

Researchers identify novel genetic signature with prognostic value for certain breast cancers

Brazilian researchers create hepatic organoids by 3D bioprinting

Scientists reveal brain mechanisms and functional regions that underlie confirmation bias

Study finds new drivers of destructive inflammation

Combination of two antibiotics eradicates latent tuberculosis in macaques

Study shows the effect of obesity on routine blood tests in children

Smart, nature-inspired system provides continuous information on patient’s health

Antioxidant in green tea plant could be key to fighting tuberculosis

Stroke drug improves stem cell therapy in rat spinal cord injury models

ELRIG UK and British Pharmacological Society form strategic alliance to improve education, drive drug discovery

Study shows nilotinib drug is safe and well tolerated in patients with Parkinson's disease

Simple, new test can detect dangerous levels of fluoride in drinking water

Tackling antibiotic resistance head-on with CRISPR

Higher temperatures and increased rainfall could make RSV epidemics less severe, more common

Evolutionarily novel genes found to be expressed in tumors

Study suggests link between bacteria in the upper airway and asthma severity

The evidence for BRCA1/2 or any genetic testing in breast cancer patients

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