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Longer looks: In-depth in the ER; Brains are saved as high school football season begins

Eric Morgan, in his 20s and planning to get married, arrives at Highland Hospital's emergency room, shaken that he has been diagnosed with a testicular tumor that is likely cancer. Surgeons at a private hospital have turned him away for lack of insurance but tell him it's "urgent" he get care.

28 Sep 2012

OncoGenex commences custirsen Phase 3 trial in non-small cell lung cancer

OncoGenex Pharmaceuticals, Inc. announced today the initiation of ENSPIRIT, a Phase 3 trial evaluating custirsen for the treatment of advanced or metastatic non-small cell lung cancer (NSCLC) in patients who have progressed after initial chemotherapy treatment has failed.

28 Sep 2012

KSU creates simple blood test that can accurately detect lung and breast cancer’s early stages

Researchers at Kansas State University have developed a simple blood test that can accurately detect the beginning stages of cancer.

27 Sep 2012

Karolinska Institutet scientists discover new approach to treat type II diabetes

An international team of scientists, led from Karolinska Institutet in Sweden, have discovered an entirely new approach to the treatment of type II diabetes. The therapy involves the blockade of signalling by a protein known as VEGF-B and this prevents fat from accumulating in the 'wrong' places, such as in muscles and in the heart. As a result the cells within these tissues are once again able to respond to insulin.

27 Sep 2012

Enrollment complete in Boehringer Ingelheim’s nintedanib phase III studies for IPF

Boehringer Ingelheim Pharmaceuticals, Inc. announced that clinical trial enrollment has completed for two phase III studies evaluating the safety and efficacy of nintedanib (BIBF 1120), an investigational compound, in patients with idiopathic pulmonary fibrosis (IPF), being studied at a twice-daily oral dose.

27 Sep 2012

CivaTech Oncology receives NIH/NCI Phase II Contract for CivaSheet device to treat NSCLC

CivaTech Oncology, an RTP medical device company dedicated to developing novel radiation therapy devices, announced the award of a $1M Phase II Contract from the National Institutes of Health and the National Cancer Institute to further develop and commercialize CivaSheet, a bioabsorbable uni-directional device for treatment of non-small-cell lung cancer.

26 Sep 2012

Researchers characterize brain's immune response to infiltrating metastases

Brain metastases are common secondary complications of other types of cancer, particularly lung, breast and skin cancer. The body's own immune response in the brain is rendered powerless in the fight against these metastases by inflammatory reactions. Researchers at the MedUni Vienna have now, for the first time, precisely characterised the brain's immune response to infiltrating metastases. This could pave the way to the development of new, less aggressive treatment options.

26 Sep 2012

High concentrations of inhaled oxygen during and after cancer surgery may increase risk of death

Patients given high concentrations of inhaled oxygen during and after cancer surgery may be at higher long-term risk of death, according to a report in the October issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

26 Sep 2012

Differences in viral illness patterns play a role in asthma development in urban, suburban children

Children living in low-income urban areas appear especially prone to developing asthma, possibly related to infections they acquire early in life. In a new study in The Journal of Infectious Diseases, available online, researchers from the University of Wisconsin in Madison investigated viral respiratory illnesses and their possible role in the development of asthma in urban versus suburban babies.

26 Sep 2012

Pervenio Lung RS from Life Technologies

Life Technologies Corporation today announced the launch of Pervenio Lung RS. First-of-its-kind, the molecular test has been documented to reliably identify early stage lung cancer patients who are at high risk for mortality following surgery. It also fulfills an unmet need for prognostic information to guide preventative treatment and improve disease management.

25 Sep 2012

Chronic respiratory disease treatments: an interview with Dr Sven Jan-Anders Karlsson, CEO of Verona Pharma

There are many different chronic respiratory diseases. Verona Pharma is mainly focused on two diseases: asthma and COPD. Asthma is a very common disease and unfortunately it has been increasing in prevalence in developed countries. This is the same with COPD; however, there may be different reasons for this.

25 Sep 2012

NanoBio to present data from preclinical studies at 8th Annual International RSV Symposium

NanoBio Corporation announced today it will present data from three preclinical studies at the 8th Annual International Respiratory Syncytial Virus (RSV) Symposium taking place from Sept. 27-30 in Santa Fe, N.M.

25 Sep 2012

Small fragments of keratin protein in the eye play a key role in warding off pathogens

When it comes to germ-busting power, the eyes have it, according to a discovery by University of California, Berkeley, researchers that could lead to new, inexpensive antimicrobial drugs.

25 Sep 2012

Anti-cancer EGFR inhibitors effective in reversing memory loss in animal models of Alzheimer's

A team of neuroscientists and chemists from the U.S. and China today publish research suggesting that a class of currently used anti-cancer drugs as well as several previously untested synthetic compounds show effectiveness in reversing memory loss in two animal models of Alzheimer's disease.

25 Sep 2012

New nanotechnology detects micrometastases in mouse models of breast cancer

Malignant cells that leave a primary tumor, travel the bloodstream and grow out of control in new locations cause the vast majority of cancer deaths. New nanotechnology developed at Case Western Reserve University detects these metastases in mouse models of breast cancer far earlier than current methods, a step toward earlier, life-saving diagnosis and treatment.

25 Sep 2012

ESMO Designated Center of Integrated Oncology and Palliative Care accreditation for 16 new centers

The European Society for Medical Oncology has awarded ESMO Designated Center of Integrated Oncology and Palliative Care accreditation to 16 new oncology centers. The centers will receive the acknowledgment at the ESMO 2012 Congress, in Vienna, Austria, 28 September - 2 October.

24 Sep 2012

Conceptually novel mechanism for biological regulation of cell suicide

Death plays a big role in keeping things alive. Consider the tightly orchestrated suicide of cells--a phenomenon essential to everything from shaping an embryo to keeping it free of cancer later in life. When cells refuse to die, and instead multiply uncontrollably, they become what we call tumors. An intricate circuitry of biochemical reactions inside cells coordinates their self-sacrifice. Tracing that circuitry is, naturally, an important part of cancer research.

24 Sep 2012

NanoViricides’ oral FluCide dramatically improves survival in animals with H3N2 influenza A

NanoViricides, Inc. reported today that its oral FluCide drug candidates demonstrated dramatically improved survival in animals administered a lethal dose of the H3N2 influenza A virus.

24 Sep 2012

Even partially matched bone marrow transplants can eliminate sickle cell disease in some patients

In a preliminary clinical trial, investigators at Johns Hopkins have shown that even partially matched bone marrow transplants can eliminate sickle cell disease in some patients, ridding them of painful and debilitating symptoms and the need for a lifetime of pain medications and blood transfusions.

24 Sep 2012

Boehringer Ingelheim completes enrollment in nintedanib Phase III trials for IPF

Boehringer Ingelheim is pleased to announce the last patients have been randomised into the Phase III sister trials assessing the efficacy and safety of nintedanib (150 mg twice daily) in patients with idiopathic pulmonary fibrosis (IPF).

24 Sep 2012

Lungs News and Research

Longer looks: In-depth in the ER; Brains are saved as high school football season begins

OncoGenex commences custirsen Phase 3 trial in non-small cell lung cancer

KSU creates simple blood test that can accurately detect lung and breast cancer’s early stages

Karolinska Institutet scientists discover new approach to treat type II diabetes

Enrollment complete in Boehringer Ingelheim’s nintedanib phase III studies for IPF

CivaTech Oncology receives NIH/NCI Phase II Contract for CivaSheet device to treat NSCLC

Researchers characterize brain's immune response to infiltrating metastases

High concentrations of inhaled oxygen during and after cancer surgery may increase risk of death

Differences in viral illness patterns play a role in asthma development in urban, suburban children

Pervenio Lung RS from Life Technologies

Chronic respiratory disease treatments: an interview with Dr Sven Jan-Anders Karlsson, CEO of Verona Pharma

NanoBio to present data from preclinical studies at 8th Annual International RSV Symposium

Small fragments of keratin protein in the eye play a key role in warding off pathogens

Anti-cancer EGFR inhibitors effective in reversing memory loss in animal models of Alzheimer's

New nanotechnology detects micrometastases in mouse models of breast cancer

ESMO Designated Center of Integrated Oncology and Palliative Care accreditation for 16 new centers

Conceptually novel mechanism for biological regulation of cell suicide

NanoViricides’ oral FluCide dramatically improves survival in animals with H3N2 influenza A

Even partially matched bone marrow transplants can eliminate sickle cell disease in some patients

Boehringer Ingelheim completes enrollment in nintedanib Phase III trials for IPF

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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