Sep 25 2012
NanoBio®
Corporation announced today it will present data from three
preclinical studies at the 8th
Annual International Respiratory Syncytial Virus (RSV) Symposium
taking place from Sept. 27-30 in Santa Fe, N.M.
The following presentations will occur on Friday, Sept. 28 at 9:30 -
10:30 a.m. Mountain Time:
Poster Presentation 51: "Whole virus RSV vaccine induced protective
immunity with reduced lung histopathology compared to recombinant F
protein RSV vaccine."
Poster Presentation 49: "Intranasal and Intramuscular Routes of RSV
Vaccine Administration Serve to Highlight the Role of Th2 and Th17 in a
Mouse RSV Challenge Model."
Poster Presentation 45: "Immunogenicity and efficacy of Line 19 RSV
vaccine in cotton rats."
During the presentations, NanoBio will share preclinical data on its
nanoemulsion adjuvanted intranasal RSV vaccine which:
-
Demonstrated improved viral clearance and reduced histopathology in an
RSV mouse challenge model.
-
Resulted in viral clearance from the lung associated with Th17
generation that is highly correlated with lower airway
hyper-reactivity (AHR).
-
Generated robust immune responses that are protective against a
heterologous A2 challenge in cotton rats.
NanoBio's RSV vaccine uses nanoemulsion technology as an intranasal
adjuvant and delivery system derived from its clinically-validated
NanoStat® technology platform.
Source: NanoBio Corporation