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Oncogene signatures could help design new drug treatments for breast cancer

Drug treatments for breast cancer patients might soon be designed based on the unique genetic autograph of their tumor.

25 Jun 2016

KIT researchers develop 3D prostate model based on cryogels

A team of researchers led by Dr. Friederike J. Gruhl and Professor Andrew C. B. Cato at Karlsruhe Institute of Technology are developing a three-dimensional model for prostate cancer research based on cryogels.

25 Jun 2016

Researchers tune into previously unknown cross talk between estrogen and progesterone receptors

One of the first clues pathologists look for in tissue from a newly diagnosed breast cancer patient is the estrogen receptor, a nuclear protein that converts hormonal messages in the bloodstream into instructions for the cell about how to behave

24 Jun 2016

3D-printed model guides doctors to safely remove tumor from kidney

Doctors and scientists at Intermountain Medical Center in Salt Lake City printed and used a 3D kidney to help save a patient's organ during a complicated tumor-removal procedural.

24 Jun 2016

Neurofibromatosis causes benign tumor formation in normal nervous tissue

Although neurofibromatosis (NF) is not commonly discussed, it affects more than 2 million people worldwide.

24 Jun 2016

Researchers identify new potential target for pancreatic cancer treatment

Using an innovative approach to identify a cancer's genetic vulnerabilities by more swiftly analyzing human tumors transplanted into mice, researchers have identified a new potential target for pancreatic cancer treatment, published online in Cell Reports.

24 Jun 2016

New insights into cancer cell signaling could help prevent metastases

Research published yesterday in Nature Communications has revealed a previously unknown mechanism by which metastasising cancer cells survive when they break away from the primary tumour. It is hoped that the discovery could help with the development of novel cancer treatments that prevent metastasis.

24 Jun 2016

Researchers reveal integrins could be key to survival mechanism in cancer cells

Cancer cells appear to depend on an unusual survival mechanism to spread around the body, according to an early study led by Queen Mary University of London. The discovery could help with future development of novel treatments to prevent metastasis and secondary tumours.

24 Jun 2016

Gamma-ray irradiation improves safety of stem cell transplantation in Parkinson’s disease patients

Replacing dopamine-producing cells in the brain represents a promising therapeutic approach in Parkinson's disease, and a new study shows how post-transplantation gamma-ray irradiation can reduce the risk of tumor formation.

24 Jun 2016

Yale-led study shows how EGFR silences tumor suppressor genes

A Yale-led study describes how a known cancer gene, EGFR, silences genes that typically suppress tumors. The finding, published in Cell Reports, may lead to the development of more effective, individualized treatment for patients with lung cancer and other cancer types.

24 Jun 2016

Taking ipilimumab, nivolumab drugs may increase risk of developing rheumatologic diseases

Case reports on 13 cancer patients suggest that a small number of cancer patients taking the immunotherapy drugs ipilimumab and nivolumab may be at some higher-than-normal risk of developing autoimmune joint and tissue diseases, including inflammatory arthritis, according to a preliminary study by Johns Hopkins Medicine researchers.

24 Jun 2016

Scientists streamline total synthesis of uncialamycin drug

A team led by Rice University scientists has improved the production of a potent anti-tumor antibiotic known as uncialamycin.

23 Jun 2016

Pre-operative MRI for breast cancer patients may need to be done in a different position

The difference in how a woman is positioned during MRI prior to breast conserving surgery and how she is positioned during the surgery distorts and displaces tumors while the surgery is being performed, report researchers.

23 Jun 2016

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

A team led by researchers at St. Jude Children's Research Hospital report that mice lacking the protein Alix develop hydrocephalus or "water on the brain." Alix ensures that epithelial cells of the choroid plexus are oriented correctly with respect to one another to prevent compromise of the epithelial barrier.

23 Jun 2016

Novel combination therapy slows cancer growth in patients with advanced solid tumors

A phase 1 clinical trial testing a novel combination therapy developed by scientists at VCU Massey Cancer Center slowed the growth of cancer in the majority of trial participants, which were patients with advanced solid tumors.

22 Jun 2016

Researchers seek to develop novel antibody to treat glioblastoma

Scientists of Helmholtz Zentrum München and the Munich University Hospital are developing a novel antibody to treat brain tumors.

22 Jun 2016

Moffitt researchers develop mathematical model to show differences in subpopulations of tumors

Tumors are composed of many subpopulations of cells. A general consensus among scientists is that these subpopulations are due to random mutations. However, Moffitt Cancer Center researchers found that these assumptions may be incorrect.

22 Jun 2016

New CAR-based therapy using combined cancer target could be effective for solid tumors

Chimeric antigen receptors (CARs), engineered from a patient's own immune cells, have been successful for treating blood cancers, but using CARs for solid tumors has been limited by side effects to normal tissues containing the protein targeted by the engineered cells.

22 Jun 2016

Kidney transplant recipients with inflammation prior to surgery more likely to develop diabetes

Up to 30 percent of people who receive organ transplants will develop diabetes, but researchers are unsure why. Although doctors typically blame immunosuppressive drugs that transplant recipients take to prevent organ rejection, it's unclear why some people develop the lifelong disorder, while others do not.

21 Jun 2016

University education linked to higher risk of brain tumor

Men and women with a university degree are more prone to developing a brain tumor than people who do not take up higher education, according to an observational study published in the Journal of Epidemiology & Community Health.

21 Jun 2016

Tumor News and Research

Oncogene signatures could help design new drug treatments for breast cancer

KIT researchers develop 3D prostate model based on cryogels

Researchers tune into previously unknown cross talk between estrogen and progesterone receptors

3D-printed model guides doctors to safely remove tumor from kidney

Neurofibromatosis causes benign tumor formation in normal nervous tissue

Researchers identify new potential target for pancreatic cancer treatment

New insights into cancer cell signaling could help prevent metastases

Researchers reveal integrins could be key to survival mechanism in cancer cells

Gamma-ray irradiation improves safety of stem cell transplantation in Parkinson’s disease patients

Yale-led study shows how EGFR silences tumor suppressor genes

Taking ipilimumab, nivolumab drugs may increase risk of developing rheumatologic diseases

Scientists streamline total synthesis of uncialamycin drug

Pre-operative MRI for breast cancer patients may need to be done in a different position

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

Novel combination therapy slows cancer growth in patients with advanced solid tumors

Researchers seek to develop novel antibody to treat glioblastoma

Moffitt researchers develop mathematical model to show differences in subpopulations of tumors

New CAR-based therapy using combined cancer target could be effective for solid tumors

Kidney transplant recipients with inflammation prior to surgery more likely to develop diabetes

University education linked to higher risk of brain tumor

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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