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Cytoreductive nephrectomy can extend survival of metastatic kidney cancer patients

Surgery to remove a cancerous kidney can often lengthen the lives of patients receiving targeted therapy for metastatic kidney cancer, but only about three in ten such patients undergo the procedure, according to a new study by researchers at Dana-Farber Cancer Institute and Brigham and Women's Hospital.

21 Jun 2016

Scientists identify on/off obesity-induced switch to slow cancer progression

Having established that excessive fat tissue can fuel the growth of certain cancers, researchers have turned their attention to the molecular mechanisms involved in the process in the hopes of developing new cancer treatments.

21 Jun 2016

Benign brain tumors less likely to emerge in people with high blood sugar

In a surprising twist, benign brain tumors that have previously been tied to obesity and diabetes are less likely to emerge in those with high blood sugar, new research has found.

21 Jun 2016

Breast cancer cells use new signaling pathway to cope with lack of oxygen levels inside tumors

Researchers have identified a new signaling pathway that helps cancer cells cope with the lack of oxygen found inside tumors. These are the results of a study published in Nature Cell Biology on June 20, and led by researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center, Princess Margaret Cancer Center, the University of Toronto, Harvard Medical School and Oxford University.

21 Jun 2016

TUM researchers uncover molecular mechanism of thalidomide

In the 1950s, thalidomide (Contergan) was prescribed as a sedative drug to pregnant women, resulting in a great number of infants with serious malformations. Up to now, the reasons for these disastrous birth defects have remained unclear.

20 Jun 2016

Scientific paper supports concept of CarThera's intracranial ultrasound implant to disrupt blood-brain barrier

CarThera, a French company based at the Brain and Spine Institute, that designs and develops innovative ultrasound-based medical devices to treat brain disorders, today announces the publication in Science Translational Medicine of a scientific paper on initial successes in disrupting the blood-brain barrier (BBB) with the use of ultrasound.

20 Jun 2016

Researchers develop AI-powered systems to make pathologic diagnoses more accurate

Pathologists have been largely diagnosing disease the same way for the past 100 years, by manually reviewing images under a microscope. But new work suggests that computers can help doctors improve accuracy and significantly change the way cancer and other diseases are diagnosed.

20 Jun 2016

Researchers uncover potential therapeutic benefit of PI3K protein in PanNETs

Researchers from the 'Angiogenesis signaling pathways' research group of the Institute of Biomedical Investigation of Bellvitge, led by Dr. Mariona Graupera, have unveiled the potential therapeutic benefit of a selective inhibitior of the PI3-kinase (PI3K) protein in pancreatic neuroendocrine tumors (PanNETs).

17 Jun 2016

Review sheds light on current therapeutic targets of miRNA-associated chemoresistance in EOC

Epithelial ovarian cancer (EOC) is the most lethal disease among gynecologic malignancies. Patients with an advanced disease often relapse due to the development of chemoresistance. Chemotherapy failure is a consequence of acquired drug resistance which may potentially be due to multiple mechanisms including miRNA-mediated gene regulation.

17 Jun 2016

New research helps better understand role of TIP60 in allowing tumors to survive in low-oxygen environments

In summer 2011, University of Colorado Cancer Center investigators Joaquín Espinosa, PhD, and Matthew Galbraith, PhD, taught a summer symposium on gene expression at Cold Spring Harbor Laboratory in Long Island, New York.

17 Jun 2016

New research paves way for potential notch-based anticancer therapeutics

A recent study led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, in collaboration with the Univerity of Maryland School of Pharmacy and StemSynergy Therapeutics, Inc., has identified a small-molecule inhibitor of the Notch pathway, paving the way for a potential new class of personalized cancer medicines.

16 Jun 2016

Researchers suggest shorter HF-WBI course as preferred option for early-stage breast cancer patients

Early-stage breast cancer patients receiving a shorter course of whole breast radiation with higher radiation doses per fraction reported equivalent cosmetic, functional and pain outcomes over time as those receiving a longer, lower-dose per fraction course of treatment, according to researchers from The University of Texas MD Anderson Cancer Center.

16 Jun 2016

Diet modification could help improve quality of life in women with ovarian cancer

New research conducted at the University of Alabama at Birmingham has shown that a particular type of diet could help women with ovarian cancer to lose weight and improve their quality of life and cancer-related measures.

16 Jun 2016

Novel imaging technique may assist surgeons to improve visualization of ovarian tumors during surgery

A newly devised tumor-specific fluorescent agent and imaging system guided surgeons in real time to remove additional tumors in ovarian cancer patients that were not visible without fluorescence or could not be felt during surgery.

15 Jun 2016

Study ignores possibility that drugs, chemicals affect sexes differently

Many of the medicines we take were only ever tested on men during clinical studies. This poses a distinct danger that females are receiving suboptimal care—and that treatments specifically benefiting women are going undiscovered.

15 Jun 2016

CT-derived SULps can improve accuracy of PET imaging in advanced cancer patients

Cancer patients often experience significant fluctuations in weight and lean body mass (LBM). Neglecting to account for these changes can prevent clinicians from obtaining precise data from molecular imaging, but a new method of measuring LBM takes changes in individual body composition into account for better staging of disease and therapy monitoring, say researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging.

15 Jun 2016

Interdisciplinary approach to improve cancer treatments

Whether it focuses on determining why certain cancers develop drug resistance, finding a way to improve individual's immune systems or better understanding cancer cell evolution, fundamental scientific research will "stand up to cancer" with three new awards from the National Science Foundation.

15 Jun 2016

PharmaMar announces initiation of pivotal plitidepsin clinical trial in patients with T-cell lymphomas

PharmaMar today announced the start of a multicenter, prospective, pivotal study to analyze the efficacy of the antitumoral compound of marine origin, plitidepsin in patients with relapsed and refractory angioimmunoblastic T-cell lymphoma.

15 Jun 2016

Four miRNAs may hold vital clue to disease progression in gliobastoma

Scientists at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich have developed a new method of predicting disease progression in gliobastoma patients who have undergone standard treatment.

14 Jun 2016

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Non-small cell lung cancers have a collective reputation for not responding very well to chemotherapy. Researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) are presenting a means of evaluating an immunotherapy that fights off NSCLC by strengthening a patient's own immune system.

14 Jun 2016

Tumor News and Research

Cytoreductive nephrectomy can extend survival of metastatic kidney cancer patients

Scientists identify on/off obesity-induced switch to slow cancer progression

Benign brain tumors less likely to emerge in people with high blood sugar

Breast cancer cells use new signaling pathway to cope with lack of oxygen levels inside tumors

TUM researchers uncover molecular mechanism of thalidomide

Scientific paper supports concept of CarThera's intracranial ultrasound implant to disrupt blood-brain barrier

Researchers develop AI-powered systems to make pathologic diagnoses more accurate

Researchers uncover potential therapeutic benefit of PI3K protein in PanNETs

Review sheds light on current therapeutic targets of miRNA-associated chemoresistance in EOC

New research helps better understand role of TIP60 in allowing tumors to survive in low-oxygen environments

New research paves way for potential notch-based anticancer therapeutics

Researchers suggest shorter HF-WBI course as preferred option for early-stage breast cancer patients

Diet modification could help improve quality of life in women with ovarian cancer

Novel imaging technique may assist surgeons to improve visualization of ovarian tumors during surgery

Study ignores possibility that drugs, chemicals affect sexes differently

CT-derived SULps can improve accuracy of PET imaging in advanced cancer patients

Interdisciplinary approach to improve cancer treatments

PharmaMar announces initiation of pivotal plitidepsin clinical trial in patients with T-cell lymphomas

Four miRNAs may hold vital clue to disease progression in gliobastoma

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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