Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Updated website reflects major developments in identification, management of chronic hepatitis C

A website developed by the American Association for the Study of Liver Diseases and the Infectious Diseases Society of America to provide up-to-date guidance on the management of hepatitis C was recently revised to reflect important developments in the identification and management of chronic hepatitis C (HCV).

4 Dec 2019

Leaky gut and space flight – the mechanism revealed

A new study on the effects of simulated microgravity, the condition that astronauts face in space, interferes with the epithelial barrier of the intestine, and the effect persists even after the astronaut returns to a normal environment. The research is published in the journal Scientific Reports.

28 Nov 2019

Life expectancy in the United States steadily decreasing

Life expectancy in the United States is decreasing, and it may be due to the increasing rates of drug abuse and suicide, a new study finds.

27 Nov 2019

New wearable sensor for non-invasive gout detection

Biomedical scientists are working hard to create more pain-free methods of disease detection and treatment. A simple blood test is highly informative but arouses intense anxiety in many people. Now a new paper published in the journal Nature Biotechnology on November 25, 2019, reports on a new wearable sensor that can be successfully adapted to mass production, is flexible, and can be used to produce readouts of metabolites and nutrients in the blood based on a sweat analysis.

26 Nov 2019

Space travel can affect intestinal function of astronauts

Bacteria, fungi, and viruses can enter our gut through the food we eat. Fortunately, the epithelial cells that line our intestines serve as a robust barrier to prevent these microorganisms from invading the rest of our bodies.

26 Nov 2019

Study shows how drinking patterns reprogram circadian metabolism in the liver

Drinking alcohol is a widespread habit in modern society and can have serious metabolic consequences. Recent studies have uncovered the interplay between nutrition, metabolism and circadian rhythms. But, until now, little has been done to understand the effects of alcohol consumption on circadian metabolism.

22 Nov 2019

One surgery to tackle two life threatening diseases

Juan Cueto did not feel sick, but he was losing weight rapidly and was devastated with the knowledge that he had two life threatening diseases, cancer and a liver disease.

20 Nov 2019

Breakthrough therapy could improve health and survival in people with cystic fibrosis

Researchers at the Children's Hospital Colorado Breathing Institute, one of the largest cystic fibrosis clinical care centers in the U.S., are part of a Therapeutics Development Network that oversaw clinical trials leading to FDA approval of TRIKAFTA, a new, highly-effective CF treatment for people with CF 12 years of age and older.

20 Nov 2019

Applying a Proteomics-based Approach to the Clinic

Matthias Mann explains why applying proteomics-based technologies such as timsTOF could accelerate the diagnosis and prediction of human disease.

From Bruker Life Sciences Mass Spectrometry 20 Nov 2019

Ammonia levels do not guide clinical management of hepatic encephalopathy in cirrhotic patients

The liver performs several critical functions including filtering blood, detoxifying chemicals and metabolizing drugs.

19 Nov 2019

Good fitness linked to longer life without dementia

It is important to say that it is never too late to begin exercising. The average participant in our study was around 60 years old at baseline, and improvement in cardiorespiratory fitness was strongly linked to lower dementia risk.

14 Nov 2019

Study shows potential of phage therapy to treat alcoholic liver disease

Bacteriophages (phages) are viruses that specifically destroy bacteria. In the early 20th century, researchers experimented with phages as a potential method for treating bacterial infections.

13 Nov 2019

Researchers use phage therapy to successfully treat alcoholic liver disease

Researchers have successfully used bacteriophage (phage) therapy to eliminate alcohol-related liver disease in an animal model.

13 Nov 2019

Impaired liver function during pregnancy can lead to impaired metabolism and weight gain

Impaired liver function during pregnancy may alter gut bacteria composition and increase the risk of obesity in children, according to results presented at The Society for Endocrinology Annual Conference.

11 Nov 2019

Study finds fewer new cases of HCV in HIV-negative men who have sex with PrEP-using men

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found fewer new cases of hepatitis C infection (commonly called HCV), despite very high rates of other sexually-transmitted infections, in HIV-negative men who have sex with men who take pre-exposure prophylaxis (PrEP) treatments.

10 Nov 2019

Study finds lower levels of liver decompensation in pregnant women with cirrhosis

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases and funded by the AASLD Foundation – found that less than two percent of pregnant women with cirrhosis had liver decompensation within one year of delivery, and their odds of decompensation is much lower than non-pregnant women with cirrhosis.

10 Nov 2019

HCC and cirrhosis-related deaths may be prevented by lifestyle modifications

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that a substantial burden of hepatocellular carcinoma and cirrhosis-related deaths may be prevented by lifestyle modifications to diet, alcohol use and exercise.

10 Nov 2019

Botanical product kratom may cause liver toxicity and injury, study finds

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that kratom, a popular and widely available product, may cause liver toxicity and severe liver injury.

10 Nov 2019

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

For the first time, a study led by researchers at Helmholtz Zentrum München and the German Center for Diabetes Research shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels differently during day and night, feeding and fasting, rest and activity, over the course of 24 hours.

10 Nov 2019

Many teens may develop nutritional deficiencies years after bariatric surgery

The good news: bariatric surgery can be a life-changer for severely obese teens. Not only do young people experience dramatic weight loss, they also benefit from near-immediate improvement of diabetes plus longer-term reductions in heart health risks.

10 Nov 2019