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New approach can improve the activity of CAR-T cells against blood and solid cancers

A new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiveness against human cancer cells grown in the laboratory and in mice, according to a study by researchers at the Stanford University School of Medicine.

5 Dec 2019

Manuka honey fights infection in surgical dressings

And now, Manuka honey is proving a gamechanger in the fight against extremely drug-resistant infections, according to a new study published in the journal Frontiers.

5 Dec 2019

Study examines injury rate during high-intensity functional training

High-intensity group workout classes are increasingly popular at fitness centers. While research has shown that these workouts can have cardiovascular and other benefits, few studies have been conducted on whether they lead to more injuries.

5 Dec 2019

Early diagnosis and treatment of chronic inflammation may reduce illness, save lives

Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.

5 Dec 2019

Mount Sinai receives $1 million grant to advance understanding of prostate cancer

The Milton and Carroll Petrie Department of Urology at the Icahn School of Medicine at Mount Sinai has received a $1 million grant from The Arthur M. Blank Family Foundation.

5 Dec 2019

New method to improve skeleton of common chemicals

Every chemical, from the simplest to the most complex, have a structural skeleton of atoms. The atoms can be added or removed to transform the chemical into different types, for use in different applications. For many pharmaceutical and agricultural chemicals, the skeleton consists of a multi-membered carbon ring called a carbocycle.

5 Dec 2019

Time-restricted eating can help treat metabolic syndrome

Metabolic syndrome affects nearly 30 percent of the U.S. population, and increases the risk for type 2 diabetes, heart disease and stroke. But lifestyle interventions such as adopting a healthy diet and increasing physical exercise are difficult to maintain and, even when combined with medication, are often insufficient to fully manage the disease.

5 Dec 2019

Overabundance of novel gene in aggressive form of ovarian cancer may serve as prognostic tool

Investigators at Rutgers Cancer Institute of New Jersey have determined that an overabundance of a novel gene known as ADNP in an aggressive form of ovarian cancer may serve as a prognostic tool.

5 Dec 2019

Molecular makeup of abnormal proteins in brain diseases shows structural diversity

Parkinson's and multisystem atrophy - both of them neurodegenerative diseases - are associated with the accumulation of alpha-synuclein proteins in the brain.

4 Dec 2019

Epigenomic techniques used to fight disease

Humans differ from one another in many ways, including how they react to disease, because of their DNA blueprint, as well as the difference in the environments they face. These factors combine to make each person unique. Now a new study published in the journal Nature Protocols reports the development of a promising technology to uncover the process by which the body fights diseases in different ways.

4 Dec 2019

New method for discovering potential cancer-treating compounds

A new study published in the journal Cell Reports reports a novel method by which antitumor drugs that focus on reawakening exhausted immune cells called cytotoxic T cells against cancer can be quickly identified. This could help treat a large subset of cancers that thrive because of their ability to suppress antitumor activity in T cells.

4 Dec 2019

Scientists create artificial neurons that help cure chronic diseases

Artificial brain cells could now be implanted in the brain to repair the damage caused by chronic diseases, such as Alzheimer’s disease and other neurodegenerative conditions, thanks to a team of scientists who created bionic neurons that work like the real thing.

4 Dec 2019

Early adherence step in intestinal transit of Shigella discovered

The bacterial pathogen Shigella, often spread through contaminated food or water, is a leading cause of mortality in both children and older adults in the developing world.

4 Dec 2019

FDA-approved drug repairs gut leakiness associated with ulcerative colitis

A research team led by biomedical scientists at the University of California, Riverside, has found that a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis can repair permeability defects in the gut's epithelium.

4 Dec 2019

New technology developed for treatment of children suffering from respiratory diseases

A new technology to unblock and remove secretions from the respiratory tract of children has been developed as part of a collaboration between researchers at Ben-Gurion University of the Negev and its affiliated Soroka University Medical Center, Cincinnati Children's Hospital Medical Center, and the University of Cincinnati.

4 Dec 2019

Cleveland Clinic to study ecological, evolutionary mechanisms that contribute to lung cancer

Jacob Scott, M.D., Ph.D., a physician researcher from Cleveland Clinic's Department of Translational Hematology and Oncology Research, recently received a $2.8 million grant from the National Cancer Institute, part of the National Institutes of Health, to study how ecological and evolutionary mechanisms contribute to lung cancer development and progression, and how the interplay between these mechanisms may provide novel treatment insights.

4 Dec 2019

Newly developed cell models can open up new avenues for ocular drug discovery

Researchers at the University of Eastern Finland have developed two new cell models that can open up new avenues for ocular drug discovery. The new cell models are continuously growing retinal pigment epithelial cells, which have many benefits over the models currently used by researchers and pharmaceutical companies. The models were developed by Professor Arto Urtti's Ocular Drug Delivery group at the University of Eastern Finland.

4 Dec 2019

New discovery may bring scientists a step closer to developing hearing loss treatments

A new discovery from a team led by Massachusetts Eye and Ear researchers may bring scientists a step closer to developing treatments that regrow the lost cells that cause hearing loss.

4 Dec 2019

Study identifies improved treatment option for neuroblastoma

Neuroblastoma is a rare form of malignant tumor, primarily affecting children under the age of six. A research team led by molecular pathologist Lukas Kenner from MedUni Vienna's Department of Pathology has now discovered, through genome sequencing, that the protein ALK and the cancer gene PIM1 are involved in the development of this tumor.

4 Dec 2019

Scientist earns prestigious award for research into cell suicide

Apoptosis is a form of “cell suicide”, where a cell self-terminates, ideally as planned or programmed, enabling multi-cellular organisms to continue to live, develop and thrive.

4 Dec 2019

Laboratory News and Research

New approach can improve the activity of CAR-T cells against blood and solid cancers

Manuka honey fights infection in surgical dressings

Study examines injury rate during high-intensity functional training

Early diagnosis and treatment of chronic inflammation may reduce illness, save lives

Mount Sinai receives $1 million grant to advance understanding of prostate cancer

New method to improve skeleton of common chemicals

Time-restricted eating can help treat metabolic syndrome

Overabundance of novel gene in aggressive form of ovarian cancer may serve as prognostic tool

Molecular makeup of abnormal proteins in brain diseases shows structural diversity

Epigenomic techniques used to fight disease

New method for discovering potential cancer-treating compounds

Scientists create artificial neurons that help cure chronic diseases

Early adherence step in intestinal transit of Shigella discovered

FDA-approved drug repairs gut leakiness associated with ulcerative colitis

New technology developed for treatment of children suffering from respiratory diseases

Cleveland Clinic to study ecological, evolutionary mechanisms that contribute to lung cancer

Newly developed cell models can open up new avenues for ocular drug discovery

New discovery may bring scientists a step closer to developing hearing loss treatments

Study identifies improved treatment option for neuroblastoma

Scientist earns prestigious award for research into cell suicide

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