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Scientists debate role of AAV in causing hepatocellular carcinoma

Liver cancer can be triggered by mutations in cancer driver genes resulting from the insertion of adeno-associated virus (AAV) vectors used to deliver therapeutic genes, although this tumor-inducing role of AAV remains highly controversial.

27 May 2016

Metabolic characteristics of CRPC may open new avenues for treatment

Advanced prostate cancer is usually treated by removing androgen, the male hormone that helps it grow. Although initially effective, this treatment often leads to the tumor becoming castration resistant- a lethal condition.

27 May 2016

Gene expression patterns of normal tissue may predict survival rates of estrogen receptor-positive breast cancer patients

Breast tissue surrounding tumors could be used to gauge future survival outcomes for women with estrogen receptor-positive breast cancer, a study led by University of North Carolina Lineberger Comprehensive Cancer Center researchers has found.

27 May 2016

TSRI study shows how specific gene mutation promotes growth of aggressive tumors

Scientists at The Scripps Research Institute have caught a cancer-causing mutation in the act. A new study shows how a gene mutation found in several human cancers, including leukemia, gliomas and melanoma, promotes the growth of aggressive tumors.

27 May 2016

New hydrogel-based biochip may help in early diagnosis of bowel cancer

Researchers from the Moscow Institute of Physics and Technology, the Engelhardt Institute of Molecular Biology, the Institute of Bioorganic Chemistry and a number of other Russian research centers have developed a new method of diagnosing colorectal cancer.

27 May 2016

Mindfulness intervention provides greater resilience, less anxiety in prostate cancer patients

Men with prostate cancer who are under close medical surveillance reported significantly greater resilience and less anxiety over time after receiving an intervention of mindfulness meditation, according to a recently published pilot study from the Northwestern University Feinberg School of Medicine.

27 May 2016

Gene mutation linked to autism plays key role in formation, maturation of synapses

A new study from MIT neuroscientists reveals that a gene mutation associated with autism plays a critical role in the formation and maturation of synapses -- the connections that allow neurons to communicate with each other.

26 May 2016

Specific immune system genes may determine how long people can live with glioblastoma

Researchers have identified a group of immune system genes that may play a role in how long people can live after developing a common type of brain cancer called glioblastoma multiforme, a tumor of the glial cells in the brain.

26 May 2016

Combining sonoporation with chemotherapy drug may help improve pancreatic cancer treatment

Researchers at Haukeland University Hospital in Bergen, Norway have combined a laboratory ultrasound technique called "sonoporation" with the commercially-available chemotherapy compound Gemcitabine to increase the porosity of pancreatic cells with microbubbles and to help get the drug into cancer cells where it is needed.

26 May 2016

First large-scale proteogenomic study helps pinpoint genes that drive breast cancer

Building on data from The Cancer Genome Atlas project, a multi-institutional team of scientists has completed the first large-scale "proteogenomic" study of breast cancer, linking DNA mutations to protein signaling and helping pinpoint the genes that drive cancer.

26 May 2016

SBP scientists discover new regulator of immune responses

Research led by scientists at the Sanford Burnham Prebys Medical Discovery Institute has identified a new regulator of immune responses. The study, published recently in Immunity, sheds new light on why T cells fail to clear chronic infections and eliminate tumors.

26 May 2016

Common pain and anti-inflammation drugs may slow cancer growth

Scientists from the Florida campus of The Scripps Research Institute have found that one of the most widely prescribed pain and anti-inflammation drugs slows the growth rate of a specific kind of cancer in animal models and suggests the medication could have the same effect on other types of tumors.

26 May 2016

UofL expands oncology research with addition of 33,000 human tissue samples

The University of Louisville has expanded its oncology research strength through the addition of approximately 33,000 human tissue samples and specimens. The samples were transferred by Catholic Health Initiatives to further the shared commitment and collaboration in advancing research and action in the fight against cancer.

25 May 2016

Continuous errors in damaged DNA repair may lead to tumor formation

A group of researchers at Osaka University found that if DNA damage response (DDR) does not work when DNA is damaged by radiation, proteins which should be removed remain instead, and a loss of genetic information can be incited, which, when repaired incorrectly, will lead to the tumor formation.

25 May 2016

Multimodal therapy may improve survival of pancreatic cancer patients

In roughly one-third of pancreatic cancer patients, tumors have grown around the pancreas to encompass critical blood vessels. Conventional wisdom has long held that surgery to remove the tumors is rarely an option, and life expectancies are usually measured in months.

25 May 2016

Purdue researchers find potential way to overcome limitations posed by CAR T-cell therapy

Purdue University researchers may have figured out a way to call off a cancer cell assassin that sometimes goes rogue and assign it a larger tumor-specific "hit list."

24 May 2016

Vitamin D and androgen receptor-targeted therapy may help treat TNBC

A recent study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine revealed that triple-negative breast cancer (TNBC), which has generally been unresponsive to hormone receptor-targeted treatments, can indeed be treated using vitamin D and androgen receptor-targeted therapy.

24 May 2016

Tumor News and Research

Scientists debate role of AAV in causing hepatocellular carcinoma

Metabolic characteristics of CRPC may open new avenues for treatment

Gene expression patterns of normal tissue may predict survival rates of estrogen receptor-positive breast cancer patients

TSRI study shows how specific gene mutation promotes growth of aggressive tumors

New hydrogel-based biochip may help in early diagnosis of bowel cancer

Mindfulness intervention provides greater resilience, less anxiety in prostate cancer patients

Gene mutation linked to autism plays key role in formation, maturation of synapses

Specific immune system genes may determine how long people can live with glioblastoma

Combining sonoporation with chemotherapy drug may help improve pancreatic cancer treatment

First large-scale proteogenomic study helps pinpoint genes that drive breast cancer

SBP scientists discover new regulator of immune responses

Common pain and anti-inflammation drugs may slow cancer growth

UofL expands oncology research with addition of 33,000 human tissue samples

Continuous errors in damaged DNA repair may lead to tumor formation

Multimodal therapy may improve survival of pancreatic cancer patients

Purdue researchers find potential way to overcome limitations posed by CAR T-cell therapy

Vitamin D and androgen receptor-targeted therapy may help treat TNBC

BUSM researchers uncover genetic, epigenetic alteration overlaps in breast and ovarian cancer

Could whole-mount scanning of breast tissue lead to better clinical outcomes? An interview with Dr Martin Yaffe

Antimicrobial agent triclosan can rapidly disrupt gut bacterial communities

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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