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Ongoing treatment with nivolumab shows benefit in advanced kidney cancer patients

Only 12% of kidney cancer patients with advanced disease survive five years after their initial treatment. In a Roswell Park Cancer Institute-led study, scientists report that some patients with advanced kidney cancer who continued to receive a novel immunotherapy drug after their disease progressed saw clinical benefit.

24 May 2016

Studies explore possible link between pediatric cancer and light therapy for newborn jaundice

Two new studies raise enough questions about a possible link between childhood cancer and light therapy for newborn jaundice that clinicians should exercise caution in prescribing the treatment for infants whose jaundice is likely to resolve on its own, a pediatric oncologist from Dana-Farber/Boston Children's Cancer and Blood Disorders Center argues in an editorial published today by the journal Pediatrics.

23 May 2016

Cornell researchers develop nanoparticle-based drug delivery mechanism for combination cancer therapy

A team of researchers from Cornell University in Ithaca, New York demonstrated a drug delivery mechanism that utilizes two independent vehicles, allowing for delivery of chemically and physically dis-tinct agents.

23 May 2016

Small lipid nanocarrier may deliver chemotherapeutic drug more efficiently to brain tumor cells

Great discoveries do come in small packages. Few know that better than Ann-Marie Broome, Ph.D., who feels nanotechnology holds the future of medicine with its ability to deliver powerful drugs in tiny, designer packages.

23 May 2016

Combination of chemotherapy and immunotherapy may be effective against ovarian cancer

Inside each ovarian tumor, there are good cells and bad cells: The bad cells are fibroblasts. They work to block chemotherapy, which is why nearly every woman with ovarian cancer becomes resistant to treatment.

23 May 2016

New microfluidic device helps extract rare target cells from background cells

A team of researchers from University of Cincinnati in Cincinnati, OH have developed a novel microfluidic device, which combines the inertial effect of fluid and microscale vortices generated in microchambers, to achieve simultaneous double sorting of rare target cells and removal of background cells.

23 May 2016

Phase I study of triple drug combination shows promise in multiple myeloma patients

PharmaMar announces the positive results from a Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed and/or refractory multiple myeloma.

21 May 2016

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

For cancer to spread, the cells that take off into the bloodstream must find a tissue that will permit them to thrive. They don't just go looking, though. Instead, they actively prepare the tissue, in one case by co-opting a protein that suppresses defenses the body would otherwise mount.

21 May 2016

Two-way communication between cancer cells may be key to tumor metastasis

Two-way communication between cancer cells appears to be key to their becoming motile, clustering and spreading through metastasis, according to Rice University scientists.

21 May 2016

Malicious form of ATF2 protein drives formation of melanoma

An international collaborative study led by scientists at the Sanford Burnham Prebys Medical Discovery Institute has identified a malicious form of a protein that drives the formation of melanoma.

20 May 2016

High levels of p62 protein in liver linked to cancer recurrence

Researchers at University of California San Diego School of Medicine and Sanford Burnham Prebys Medical Discovery Institute have discovered that high levels of the protein p62 in human liver samples are strongly associated with cancer recurrence and reduced patient survival.

20 May 2016

EAD therapy can shrink size of triple-negative breast cancer tumors in mice

In a new study using mice and lab-grown human cells, a scientific team led by Johns Hopkins Kimmel Cancer Center researchers show how a triple-drug cocktail can shrink triple-negative breast cancers by killing off cancer cells and halting new tumor growth.

20 May 2016

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Chronix Biomedical, Inc., a developer of blood-based molecular diagnostics, today announces positive data from a blinded proof of concept clinical study, assessing the utility of tumor cell-free DNA as a predictor of therapeutic response to immunotherapy after the first cycle of treatment in eight different types of cancer.

20 May 2016

Researchers identify low MCJ expression as marker of poor response to chemotherapy

Chemotherapy is a key part of the standard treatment regimen for triple-negative breast cancer patients whose cancer lacks expression of estrogen and progesterone receptors and the human epidermal growth factor receptor 2 (HER2).

20 May 2016

Loss of HOXA5 protein may allow breast cancer cells to thrive

Many breast cancers are marked by a lack of HOXA5 protein, a gene product known to control cell differentiation and death, and lower levels of the protein correspond to poorer outcomes for patients.

20 May 2016

Radiation-immunotherapy combination can help treat melanoma

Combining radiation treatments with a new generation of immunotherapies is showing promise as a one-two-punch against melanoma, Loyola Medicine researchers report in a review article.

20 May 2016

Borrowed immune system may help combat cancer

A new step in cancer immunotherapy: researchers from the University of Oslo/Oslo University Hospital and the Netherlands Cancer Institute show that even if one's own immune cells cannot recognize and fight their tumors, someone else's immune cells might.

20 May 2016

Microglia plays vital role in reducing effects of cocaine in the brain

A type of brain cell known as microglia plays a key role in reducing the effects of cocaine in the brain, according to a major study by a team from the Research Institute of the McGill University Health Centre in Montreal.

20 May 2016

Combining 2-DG with fenofibrate could provide non-toxic treatments for many cancers

A team of researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine recently discovered a novel, non-toxic approach to treating a wide variety of cancers.

19 May 2016

AKR1C3 enzyme could be promising therapeutic target for managing CRPC, AML

Prostate cancer is the second leading cause of mortality among American men with the highest incidence rate of all cancers reported in the U.S. Male sex hormones testosterone (T) and 5α-dihydrotestosterone (5α-DHT) promote prostate cancer progression.

19 May 2016

Tumor News and Research

Ongoing treatment with nivolumab shows benefit in advanced kidney cancer patients

Studies explore possible link between pediatric cancer and light therapy for newborn jaundice

Cornell researchers develop nanoparticle-based drug delivery mechanism for combination cancer therapy

Small lipid nanocarrier may deliver chemotherapeutic drug more efficiently to brain tumor cells

Combination of chemotherapy and immunotherapy may be effective against ovarian cancer

New microfluidic device helps extract rare target cells from background cells

Phase I study of triple drug combination shows promise in multiple myeloma patients

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

Two-way communication between cancer cells may be key to tumor metastasis

Malicious form of ATF2 protein drives formation of melanoma

High levels of p62 protein in liver linked to cancer recurrence

EAD therapy can shrink size of triple-negative breast cancer tumors in mice

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Researchers identify low MCJ expression as marker of poor response to chemotherapy

Loss of HOXA5 protein may allow breast cancer cells to thrive

Radiation-immunotherapy combination can help treat melanoma

Borrowed immune system may help combat cancer

Microglia plays vital role in reducing effects of cocaine in the brain

Combining 2-DG with fenofibrate could provide non-toxic treatments for many cancers

AKR1C3 enzyme could be promising therapeutic target for managing CRPC, AML

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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