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RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest in response.

27 Oct 2022

Study sheds light on why some patients respond better than others to immunotherapy

Immunotherapy, a biotherapy that boosts the ability of the immune system to recognize and attack mutant tumor cells, has transformed the treatment landscape for patients battling cancer, which emerges from the progressive accumulation of DNA mutations.

27 Oct 2022

Immune checkpoint therapy may be beneficial in certain cases of severe COVID-19

An article published in Science Advances suggests that a type of cancer treatment known as immune checkpoint blockade may be beneficial in certain cases of severe COVID-19.

27 Oct 2022

UC San Diego participates in national trial to assess potential treatment for human monkeypox

The University of California San Diego will be one of multiple sites assessing the safety and efficacy of tecovirimat as a potential treatment for human monkeypox.

27 Oct 2022

OSU researchers take major step toward improving, lengthening the lives of cystic fibrosis patients

Researchers at Oregon State University and Oregon Health & Science University have taken a key step toward improving and lengthening the lives of cystic fibrosis patients, who experience chronically clogged airways and a dramatically shortened life expectancy.

27 Oct 2022

Third dose of COVID-19 mRNA vaccine offers cirrhosis patients strong protection against the virus

Cirrhosis of the liver is associated with decreased responsiveness to many vaccines, including those that protect against COVID-19.

27 Oct 2022

AKT inhibitor shows promise in a trial matching new treatments to cancer patients based on genetic make-up of tumors

In a trial matching new treatments to cancer patients based on the genetic make-up of their tumors, 22% of the patients treated with the AKT inhibitor drug ipatasertib had their tumors shrink.

27 Oct 2022

Study elucidates mechanism that is crucial for making hemophilia therapy effective

Hemophilia A is the most common severe form of hemophilia. It affects almost exclusively males. The disease can usually be treated well, but not for all sufferers.

27 Oct 2022

Advanced type of nanoparticle could help fight hard-to-treat cancers

Nanoparticles, or tiny molecules that can deliver a payload of drug treatments and other agents, show great promise for treating cancers.

27 Oct 2022

Study finds sexual dimorphism in the development of vascular insulin resistance induced by obesogenic lifestyle

A new study from the University of Missouri School of Medicine is the first evidence in humans that short-term lifestyle changes can disrupt the response to insulin of blood vessels. It's also the first study to show men and women react differently to these changes.

27 Oct 2022

Study examines the severity of the SARS-CoV-2 Omicron BA.2 subvariant

In a recent study that represents the largest to date to examine the severity of the SARS-CoV-2 Omicron BA.2 subvariant (the strain making a re-emergence this fall), a team led by investigators at Massachusetts General Hospital (MGH) determined that the BA.2 subvariant is less severe than the previous Delta variant and less severe to an even greater extent than the original Omicron variant.

27 Oct 2022

New discovery may change the textbook model of GPCR-mediated signaling

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs.

27 Oct 2022

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

A fault in cells that form a key part of the immune system can be repaired with a pioneering gene editing technique, finds new research demonstrated in human cells and mice, led by UCL scientists.

27 Oct 2022

Studies find cardiovascular effects of cigarettes and e-cigarettes to be strikingly similar

Two related studies, one in humans and the other in rats, found that the cardiovascular effects of cigarettes and e-cigarettes are strikingly similar, and these harmful effects on blood vessel function are likely caused by airway irritation due to inhalation of a foreign substance, rather than a specific component of the cigarette smoke or e-cigarette vapor (aerosol), according to new research published today in the American Heart Association's peer-reviewed journal Arteriosclerosis, Thrombosis and Vascular Biology.

27 Oct 2022

Hydrogel bioink can bioprint conduits that mimic the mechanics of native blood vessels

Cardiovascular diseases (CVDs) remain among the leading causes of global morbidity and mortality. In patients with CVD, blood vessels-which transport blood, oxygen, and nutrients-can become constricted or obstructed, leading to numerous complications.

27 Oct 2022

Some healthcare workers vaccinated against COVID-19 show unexpectedly low responses to immunizations

A subset of healthcare workers vaccinated against COVID-19 had unexpectedly low responses to the immunizations, according to Cedars-Sinai investigators.

27 Oct 2022

Unique gut bacteria could be responsible for triggering rheumatoid arthritis in at-risk people

Researchers at the University of Colorado School of Medicine have discovered that a unique bacteria found in the gut could be responsible for triggering rheumatoid arthritis (RA) in people already at risk for the autoimmune disease.

26 Oct 2022

Low-carb diet may be a useful approach for preventing and treating Type 2 diabetes

While low-carb diets are often recommended for those being treated for diabetes, little evidence exists on whether eating fewer carbs can impact the blood sugar of those with diabetes or prediabetes who aren't treated by medications.

26 Oct 2022

Multiple outpatient visits are key to success opioid-use disorder treatment

People with opioid-use disorder who enter treatment are at risk for relapse, overdose or death if they engage in less than two outpatient visits in their first month of care, according to a study coauthored by Rutgers researchers.

26 Oct 2022

Researchers report white matter differences in post-treatment Lyme disease patients

In a study using specialized imaging techniques, Johns Hopkins Medicine researchers report distinctive changes in the "white matter" and other brain tissue physiology of those with post-treatment Lyme disease, a condition affecting 10% to 20% of the nearly half a million Americans who contract Lyme disease annually.

26 Oct 2022

Medicine News and Research

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Study sheds light on why some patients respond better than others to immunotherapy

Immune checkpoint therapy may be beneficial in certain cases of severe COVID-19

UC San Diego participates in national trial to assess potential treatment for human monkeypox

OSU researchers take major step toward improving, lengthening the lives of cystic fibrosis patients

Third dose of COVID-19 mRNA vaccine offers cirrhosis patients strong protection against the virus

AKT inhibitor shows promise in a trial matching new treatments to cancer patients based on genetic make-up of tumors

Study elucidates mechanism that is crucial for making hemophilia therapy effective

Advanced type of nanoparticle could help fight hard-to-treat cancers

Study finds sexual dimorphism in the development of vascular insulin resistance induced by obesogenic lifestyle

Study examines the severity of the SARS-CoV-2 Omicron BA.2 subvariant

New discovery may change the textbook model of GPCR-mediated signaling

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

Studies find cardiovascular effects of cigarettes and e-cigarettes to be strikingly similar

Hydrogel bioink can bioprint conduits that mimic the mechanics of native blood vessels

Some healthcare workers vaccinated against COVID-19 show unexpectedly low responses to immunizations

Unique gut bacteria could be responsible for triggering rheumatoid arthritis in at-risk people

Low-carb diet may be a useful approach for preventing and treating Type 2 diabetes

Multiple outpatient visits are key to success opioid-use disorder treatment

Researchers report white matter differences in post-treatment Lyme disease patients

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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