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Mother’s diet and slimness might have long-term effects on the health of her baby

Researchers have discovered a link between the amount of blood flowing through the liver of the unborn baby in late pregnancy and the diet of expectant mums.

20 Jan 2005

Heart patients with gastrointestinal complications should use low doses of aspirin combined with drugs that treat stomach ulcers

Physicians are challenged in treating heart patients who may be at high-risk for gastrointestinal bleeding from aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). Factors that place patients at high-risk include a history of ulcers or gastrointestinal complications such as bleeding, increased age and congestive heart failure.

20 Jan 2005

Cord blood transplantation now a viable option for adult leukemia patients

Stem cell transplantation using umbilical cord blood is a standard treatment option for blood disorders in children, but not for adults, due to the difficulty of obtaining a sufficiently large dose of cells.

20 Jan 2005

Clopidogrel (Plavix®) responses appear normal in largest data set

Although individual patients respond differently to treatment with the anti-platelet medication clopidogrel (brand name Plavix®), those variations appear normal and may not indicate important differences in the effectiveness of treatment, according to a new study (PDF file) in the Jan. 18, 2005 issue of the Journal of the American College of Cardiology.

19 Jan 2005

Medicine alone may not offer best quality of life for patients with moderate heart attack risk

Routine angiography and revascularization procedures, if indicated, appear to offer better quality of life than conservative medical treatment for patients with chest pain and evidence of coronary artery disease, according to a new study (PDF file) in the Jan. 18, 2005 issue of the Journal of the American College of Cardiology.

19 Jan 2005

Scientists identify fat gene

UCLA/VA scientists have identified a new gene that controls how the body produces and uses fat. Called lipin, the gene may provide a new target for therapies to control obesity, diabetes and other weight-related disorders. The first issue of the new journal Cell Metabolism publishes the findings in its January 2005 edition.

19 Jan 2005

Doctor report cards not always clear when comparing quality of care

When choosing a doctor based on increasingly popular “doctor report cards,” patients should be aware that the areas in which physicians are graded are not always clear-cut, according to researchers from the Johns Hopkins Bloomberg School of Public Health and School of Medicine.

19 Jan 2005

Program aimed at improving the quality of treatment for depression is effective at reducing depression

An intervention for adolescents aimed at improving the quality of treatment for depression is effective at reducing depression, according to a study in the January 19 issue of JAMA.

19 Jan 2005

Do well-trained hospital staff perform CPR properly?

University of Chicago Hospitals, Chicago, and colleagues conducted a study to determine whether well-trained hospital staff perform CPR compressions and ventilations according to guideline recommendations.

19 Jan 2005

Simplified approach to the management of patients with an acute coronary syndrome

A simplified approach to the management of patients with an acute coronary syndrome (chest pain at rest or with mild exertion) can help ensure that precise risk-reducing strategies are followed to the letter by doctors and other caregivers of patients with this medical condition, according to a study by Johns Hopkins researchers.

19 Jan 2005

Screening tests find colorectal cancer in its earliest stages when it can be treated more successfully

Colorectal cancer (CRC) is second only to lung cancer as the leading cause of cancer-related death in the United States. In 2004, it’s estimated that CRC caused nearly 57,000 deaths.

18 Jan 2005

Major European research initiative in the genetics of drug addiction

The University of Surrey has announced that it is to lead a major European research initiative in the genetics of drug addiction, funded by an €8.1 million contract from the European Commission.

18 Jan 2005

Elsevier to launch journal devoted to nanomedicine

Elsevier has announced plans to launch a peer-reviewed journal devoted to nanomedicine - the emerging science of using molecular machines to treat human disease. Nanomedicine: Nanotechnology, Biology, and Medicine, the official publication of the American Academy of Nanomedicine, will be published quarterly, with the first issue to appear in March 2005.

18 Jan 2005

New insight into how tumor cells can become resistant to anti-cancer therapy

The scientists observed that a protein called P-glycoprotein (P-gp), which causes resistance to chemotherapy in many tumor types, is able to physically “jump” or transfer between tumor cells and retain its functional properties, protecting otherwise sensitive cells from the effects of anti-cancer treatment in vivo and in vitro.

18 Jan 2005

Origins of racial health disparities can involve both genes and environment and the interactions between them

New understanding of the dynamic interplay between genes and environment, made possible by technologies arising from the Human Genome Project, helps support the individualization of medicine and makes focusing on racial or ethnic group differences in disease less relevant, say Penn State researchers.

17 Jan 2005

Further evidence for the role of cyclooxygenases (COX) in heart-disease risk

In two articles, published in Circulation, researchers from the University of Pennsylvania School of Medicine provide further evidence for the role of cyclooxygenases (COX) in heart-disease risk.

17 Jan 2005

Jump starting T cells in skin cancer

Advanced melanoma, the most deadly form of skin cancer, can be successfully treated in some cases by vaccinating patients with tumor proteins.

17 Jan 2005

Few smokers make use of the help that is available

Antidepressant medicines, nicotine replacement products, and counseling can all help a smoker stick with that New Year's resolution to kick the habit. But a study by American Cancer Society researchers finds that few smokers make use of the help that is available.

17 Jan 2005

More data needed on what's effective for hot flashes

A University of Michigan expert on menopause says a new study that indicates placebos work as well as antidepressant drugs to help hot flashes shows how much more research is needed about what gives patients relief.

17 Jan 2005

Botox may help people with movement disorders

The long-term effects of botulinum toxin type A (Botox) in patients with severe movement disorders confirm the safety of the toxin's use in controlled dosages, according to a recent study at Baylor College of Medicine in Houston.

17 Jan 2005