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Time-reversal acoustics research promises medical breakthroughs

Scientists have not yet found a way to actually make time run backward, but in the cutting-edge world of recent acoustics research, they have shown a way to make sound waves run backward in a kind of ultra-focused reverse echo. By the technology known as time-reversal acoustics, sound waves - in exact reverse order from the original sound - echo directly and very precisely back to their source point.

7 Apr 2004

Women with a history of pre-eclampsia are at increased risk of cancer

Women with a history of pre-eclampsia are at increased risk of cancer, particularly cancers of the stomach, breast, ovary, lung and larynx, according to a Columbia University study recently published by the British Medical Journal. Researchers studied 37,000 women in western Jerusalem, Israel, who delivered babies in three large hospitals between 1964 and 1976.

7 Apr 2004

Lack of vigorous physical activity is the main contributor to obesity in adolescents ages 11 to 15

Lack of vigorous physical activity is the main contributor to obesity in adolescents ages 11 to 15, according to a study of 878 adolescents by researchers at the University of California, San Diego (UCSD) School of Medicine, in collaboration with investigators at San Diego State University.

6 Apr 2004

Oral sildenafil improved exercise tolerance, cardiac output and quality of life in 22 patients with primary pulmonary hypertension

Oral sildenafil (Viagra®) improved exercise tolerance, cardiac output and quality of life in 22 patients with primary pulmonary hypertension, according to the results of the first randomized, placebo-controlled, double-blind, crossover study, reported in the April 7, 2004 issue of the Journal of the American College of Cardiology.

6 Apr 2004

New method to induce embryonic stem cells to develop into bone marrow and blood cells

Researchers at Northwestern University have devised a method to induce embryonic stem cells to develop into bone marrow and blood cells. Injecting the stem cells into the bone marrow cavity of mice whose bone marrow cells had been depleted restored production of blood cells, including cells of the immune system, which normally are created in the bone marrow.

6 Apr 2004

Trauma Highly Prevalent Among Delinquents

Almost every boy and girl currently detained in a juvenile facility in the United States has experienced at least one major trauma, and a large proportion of these children have post-traumatic stress disorder, according to a study in the April issue of Archives of General Psychiatry.

6 Apr 2004

A new technique for engineering protein crystals is helping scientists figure out the three-dimensional structures of some important biological molecules

A new technique for engineering protein crystals is helping scientists figure out the three-dimensional structures of some important biological molecules, including a key plague protein whose structure has eluded researchers until now. The technique, developed with support from the National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health (NIH), promises to help pharmaceutical companies develop more effective drugs to treat various diseases by tailor-making molecules to "fit" a protein's shape.

6 Apr 2004

Scientists studying vaccinia virus, a relative of smallpox, have determined that a gene necessary for virus replication also has a key role in turning off inflammation

Scientists at the University of Illinois at Urbana-Champaign studying vaccinia virus, a close relative of smallpox, have determined that a gene necessary for virus replication also has a key role in turning off inflammation, a crucial anti-viral immune response of host cells.

6 Apr 2004

Alzheimer's live about half as long as those of similar age without dementia

Age, seriousness of impairment, and the severity of other medical conditions are important indicators of how long an individual might survive after an Alzheimer's disease diagnosis, Eric B. Larson, M.D., M.P.H. and colleagues report in the April 6 Annals of Internal Medicine. Study authors include Linda Teri, Ph.D., recipient of an Alzheimer's Association $1 million Pioneer research grant.

6 Apr 2004

Genetic cause of cancer identified as a defect in the function of otherwise normal genes

In a landmark study published today in Nature Genetics, researchers from St Vincent's Hospital, The Victor Chang Cardiac Research Institute and the University of New South Wales have shown that a possible cause of cancer is a defect in the function of otherwise normal genes.

6 Apr 2004

Number of breaths given during CPR may be linked to survival

Researchers have identified a factor that may improve cardiac arrest survival rates according to a first-of-its-kind study of paramedic responses reported in today’s rapid access issue of Circulation: Journal of the American Heart Association.

5 Apr 2004

Collaboration to create a series of small molecule drugs leads against a Takeda target

Array BioPharma Inc. today announced the commencement of a drug discovery collaboration with Takeda Chemical Industries, Ltd. to create a series of small molecule drug leads against a Takeda target. This collaboration is in addition to Array's existing research agreement with Takeda that began in 2001.

5 Apr 2004

Ohio university to get major expansion cancer program

The Ohio State University Board of Trustees today has authorized the preparation of architectural and engineering plans for a possible major expansion of the university’s cancer program.

5 Apr 2004

Research shows giving Tourette Syndrome patients the drug levodopa normalizes brain activity

Scientists have known for years that abnormal activity involving a brain chemical called dopamine is somehow connected to the movements and vocalizations, or tics, associated with Tourette syndrome. Now neuroscience researchers at Washington University School of Medicine in St. Louis have found brain activity in these patients is abnormal during memory tasks, as well.

5 Apr 2004

A simple urine sample could soon be used to predict the complex toxic effects of new drugs

BlueGnome has pioneered the use of statistical signal modelling in the analysis of high throughput experimental data. Its first product BlueFuse for Microarrays uses statistical modelling techniques to eliminate Œnoise‚ generated in microarray experiments, enabling researchers to automatically identify the presence or absence of genes and proteins with a higher level of confidence than is currently possible.

5 Apr 2004

Implantable defibrillator cuts heart attack risk of sudden death by 31%

Researchers at Loyola University Health System, Maywood, Ill., and the University of Rochester Medical Center, Rochester, N.Y., found that the previously demonstrated survival benefit of ICDs following a heart attack can last up to 15 years.

5 Apr 2004

Common cholinesterase inhibitor eases behavioral symptoms like agitation, depression, and psychosis in patients

The so-called "memory drugs" used to treat Alzheimer's disease and other causes of dementia also ease or prevent a barrage of troublesome behaviors that affect the majority of patients, ultimately lightening the burden on caregivers, researchers have found. They report their results in the March issue of the American Journal of Psychiatry.

5 Apr 2004

Missed opportunities for addressing HIV testing remain unacceptably high

The researchers, led by Jeffrey Samet, MD, professor of medicine at BUSM and chief of General Internal Medicine at Boston Medical Center (BMC), performed a 10-year retrospective chart review of patients seen at an HIV intake clinic between January 1994 and June 2001 who: 1) tested positive for HIV during the 12 months prior to their presentation at the intake clinic and 2) had one or more encounters recorded in the medical record prior to their HIV positive status.

5 Apr 2004

Cordis Cardiology receives warning from the U.S. Food and Drug Administration

Cordis Cardiology, a division of Cordis Corporation, a Johnson & Johnson Company, reported today that it received a warning letter from the U.S. Food and Drug Administration (FDA) regarding FDA's observations concerning the Good Manufacturing Practice (GMP) regulations.

5 Apr 2004

Michigan opens new center to treat exposure to Vermiculite, Taconite, Asbestos

In response to the United States Environmental Protection Agency's (EPA) identification of major sources of public asbestos exposure in Michigan, the Barbara Ann Karmanos Cancer Institute and the Center for Occupational and Environmental Medicine (COEM) affiliated with Wayne State University (WSU) have joined forces to establish The National Center for Vermiculite and Asbestos-Related Cancers.

5 Apr 2004

Medicine News and Research

Time-reversal acoustics research promises medical breakthroughs

Women with a history of pre-eclampsia are at increased risk of cancer

Lack of vigorous physical activity is the main contributor to obesity in adolescents ages 11 to 15

Oral sildenafil improved exercise tolerance, cardiac output and quality of life in 22 patients with primary pulmonary hypertension

New method to induce embryonic stem cells to develop into bone marrow and blood cells

Trauma Highly Prevalent Among Delinquents

A new technique for engineering protein crystals is helping scientists figure out the three-dimensional structures of some important biological molecules

Scientists studying vaccinia virus, a relative of smallpox, have determined that a gene necessary for virus replication also has a key role in turning off inflammation

Alzheimer's live about half as long as those of similar age without dementia

Genetic cause of cancer identified as a defect in the function of otherwise normal genes

Number of breaths given during CPR may be linked to survival

Collaboration to create a series of small molecule drugs leads against a Takeda target

Ohio university to get major expansion cancer program

Research shows giving Tourette Syndrome patients the drug levodopa normalizes brain activity

A simple urine sample could soon be used to predict the complex toxic effects of new drugs

Implantable defibrillator cuts heart attack risk of sudden death by 31%

Common cholinesterase inhibitor eases behavioral symptoms like agitation, depression, and psychosis in patients

Missed opportunities for addressing HIV testing remain unacceptably high

Cordis Cardiology receives warning from the U.S. Food and Drug Administration

Michigan opens new center to treat exposure to Vermiculite, Taconite, Asbestos

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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