Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Insulin resistance increases retinopathy and nephropathy risk in young type 1 diabetics

A study published in the journal Cardiovascular Diabetology describes the relationship between estimated glucose disposal rate (eGDR) and retinopathy or kidney disease in young adults with type 1 diabetes.

22 Mar 2023

Childhood and adolescent obesity: time to act

In a recent review published in the journal Frontiers in Pediatrics, researchers at the Medical College of Wisconsin presented an overview of the pathophysiological mechanisms, health implications, and management options for obesity among children and adults.

21 Mar 2023

Diet and exercise programs alone won't curb the tide of childhood obesity

Focusing on immediate fixes such as diet and exercise programs alone won't curb the tide of childhood obesity, according to a new study that for the first time maps the complex pathways that lead to obesity in childhood.

21 Mar 2023

Review explores trehalose's effects on metabolism and gut microflora

researchers review the bioactive properties of trehalose and its potential pharmaceutical, medical, cosmetic, and food-related applications.

20 Mar 2023

New WHO report identifies five core national targets for managing diabetes

A new report for the World Health Organization has identified five core national targets for UN member states aimed at reducing diabetes risk and ensuring that people with diabetes have equitable access to comprehensive and affordable care and prevention.

20 Mar 2023

What role does dysbiosis play in Parkinson's disease?

The current study, published in the journal Revue Neurologique, is based on the hypothesis that dysbiosis, or unhealthy variations in the gut and oral microbiota, is a key component of PD pathogenesis.

19 Mar 2023

California picks generic drug company Civica to produce low-cost insulin

Gov. Gavin Newsom on Saturday announced the selection of Utah-based generic drug manufacturer Civica to produce low-cost insulin for California, an unprecedented move that makes good on his promise to put state government in direct competition with the brand-name drug companies that dominate the market.

19 Mar 2023

Which exercises might reduce pro-inflammatory and enhance anti-inflammatory cytokines in older people with mild cognitive impairment or Alzheimer's disease?

Researchers investigated which exercises might enhance anti-inflammatory cytokines and reduce pro-inflammatory cytokines in patients with dementia or mild cognitive impairment.

17 Mar 2023

Loss of a beta cell subset might contribute to type 2 diabetes

Multiple types of beta cells produce insulin in the pancreas, helping to balance blood sugar levels. Losing a particularly productive type of beta cell may contribute to the development of diabetes, according to a new study by Weill Cornell Medicine investigators.

17 Mar 2023

Benefiting the health of people with diabetes: The WHO Global Diabetes Compact targets

Researchers described the targets of the World Health Organization's (WHOs) Global Diabetes Compact to improve the health outcomes for all individuals affected by this fatal, non-communicable disease.

17 Mar 2023

Phase 2 clinical trial investigates the effectiveness of innovative procedure to control Type 2 diabetes

More than 37 million Americans have diabetes, and approximately 90-95% have Type 2 diabetes.

16 Mar 2023

Artificial pancreas technology improves blood glucose control in young children with type 1 diabetes

Artificial pancreas technology improved blood glucose control in young children between ages 2 and 5 with type 1 diabetes, according to the results of the Pediatric Artificial Pancreas (PEDAP) Trial, a 13-week randomized controlled trial conducted at three pediatric diabetes centers across the United States.

15 Mar 2023

How does soy consumption affect the risk of type 2 diabetes and cardiovascular diseases?

A higher intake of plant protein could effectively improve metabolic health and lower CVD mortality. Recently, scientists in China reviewed existing literature and conducted a meta-analysis to understand the association between increased soy consumption and the risk of T2D and CVDs. This review is available in the journal Nutrients.

15 Mar 2023

Researchers design a virus-resistant, more useful E. coli bacteria

In a step forward for genetic engineering and synthetic biology, researchers have modified a strain of Escherichia coli bacteria to be immune to natural viral infections while also minimizing the potential for the bacteria or their modified genes to escape into the wild.

15 Mar 2023

Researchers identify a potential treatment to prevent severe COVID-19 in high-risk patients

UVA Health researchers have identified a potential treatment to prevent severe COVID-19 in patients at great risk.

15 Mar 2023

An emerging target for chronic kidney disease treatment - DNA-PKcs

A recent Nature Communications study suggested that DNA-PKcs could be a potential target for treating chronic kidney disease.

15 Mar 2023

How does dietary intervention affect aging?

Aging is a process that includes multiple interwoven mechanisms that interact with lifestyle factors. A new review seeks to encapsulate the available information on the effect of diet on aging at the cellular level in humans.

14 Mar 2023

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

The hormone glucose-dependent insulinotropic polypeptide (GIP) is considered obesogenic. In contrast, GIP receptor agonists (GIPRAs) have shown reduced feeding and body weight in an obese mouse model. Therefore, the precise effects exerted by GIP and GIPRAs remain elusive.

14 Mar 2023

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

A new study published in Science Immunology points to a promising therapeutic approach for future cancer treatments based on natural killer cells (NK), which are immune cells that bind to tumor cells and destroy them.

14 Mar 2023

Study identifies abnormal biomarkers associated with obesity in early elementary-aged Latino youth

In the United States, low-income, Latino youth are disproportionately affected by obesity with 25.8% of Latino youth aged 2-19 considered to have obesity, which is approximately two times more likely when compared to their non-Latino white counterparts.

14 Mar 2023

Insulin News and Research

Further Reading

Insulin resistance increases retinopathy and nephropathy risk in young type 1 diabetics

Childhood and adolescent obesity: time to act

Diet and exercise programs alone won't curb the tide of childhood obesity

Review explores trehalose's effects on metabolism and gut microflora

New WHO report identifies five core national targets for managing diabetes

What role does dysbiosis play in Parkinson's disease?

California picks generic drug company Civica to produce low-cost insulin

Which exercises might reduce pro-inflammatory and enhance anti-inflammatory cytokines in older people with mild cognitive impairment or Alzheimer's disease?

Loss of a beta cell subset might contribute to type 2 diabetes

Benefiting the health of people with diabetes: The WHO Global Diabetes Compact targets

Phase 2 clinical trial investigates the effectiveness of innovative procedure to control Type 2 diabetes

Artificial pancreas technology improves blood glucose control in young children with type 1 diabetes

How does soy consumption affect the risk of type 2 diabetes and cardiovascular diseases?

Researchers design a virus-resistant, more useful E. coli bacteria

Researchers identify a potential treatment to prevent severe COVID-19 in high-risk patients

An emerging target for chronic kidney disease treatment - DNA-PKcs

How does dietary intervention affect aging?

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

Study identifies abnormal biomarkers associated with obesity in early elementary-aged Latino youth

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