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Approval for FOSRENOL (lanthanum carbonate), which controls phosphate levels in renal dialysis patients

Sweden's MPA has today granted the first regulatory approval in the world for FOSRENOL (lanthanum carbonate), a non-calcium, non-aluminium phosphate binding medicine developed to control phosphate levels in renal dialysis patients. Sweden will now become the Reference Member State in the EU Mutual Recognition Procedure for FOSRENOL, and this is the first step in securing marketing approval throughout Europe. A submission has also been made by Shire to gain marketing approval for FOSRENOL in the United States.

25 Mar 2004

£5m for HIV/AIDS trial involving HIV patients in London, Moscow, South Africa and Australia

A joint Oxford University/Imperial College research programme into HIV/AIDS has received £5 million support from the Wellcome Trust to carry out a drug trial involving HIV patients in London, Moscow, South Africa and Australia.

24 Mar 2004

FDA Approves Pre-Filled Pre-Mixed Fertility Medication

The U.S. Food and Drug Administration (FDA) today announced approval of Follistim®-AQ TM cartridge (follitropin beta injection) in the United States. Follistim-AQ cartridge is the first follicle stimulating hormone (FSH) treatment available in a pre-filled, pre-mixed solution, eliminating the need for patients to mix one or more vials of medication.

24 Mar 2004

First US Tests of Bird-Flu Vaccine in Humans

Doctors are beginning the first test in the United States of a vaccine designed to protect people against one form of bird flu should an outbreak of the virus occur in humans. While the vaccine under study is not designed to protect against the precise bird-flu virus causing the current outbreak in poultry and in people, scientists will learn whether it protects against another strain of the virus that infects birds and people.

24 Mar 2004

Bone marrow stem cells do not help regenerate heart muscle tissue, UW study finds, contradicting earlier study

Researchers at the University of Washington School of Medicine have found that bone marrow stem cells do not convert into heart muscle cells in mice. These results contradict a study conducted elsewhere that had prompted human clinical trials for such stem cell therapy in the treatment of heart attack.

23 Mar 2004

Oregon Stem Cell Center Hunt for Human Disease Therapies

Oregon Health & Science University's fast-growing stem cell research program, which already has made significant strides in the hunt for human disease therapies, now has a place to call home.

23 Mar 2004

Carbon Dioxide may be used in medical implants

Carbon dioxide, an environmentally friendly solvent for dyeing and dry cleaning, may become a valuable new tool for making medical implants, according to a study at Ohio State University.

23 Mar 2004

New Cell Sorter Helps Understand Deadly Diseases

Researchers at NC State’s College of Veterinary Medicine have a new state-of-the-art tool, a high-speed cell sorter, that should quicken the pace of their research. The machine sorts or collates cells into groups, allowing scientists to look only at the cells they are working on.

23 Mar 2004

Alcohol Consumption Decreases Risk of Heart Disease in Men

Cardiovascular disease, including heart disease and stroke, is the leading cause of death in the United States. To help combat this epidemic, studies throughout the United States pinpoint dietary guidelines to reduce risk including a recent release from the American Heart Association which stated that hypertensive patients should avoid alcoholic beverages.

23 Mar 2004

System for guiding cell migration, adhesion has biomedical and regenerative medical applications

Scientists at the University of Toronto are taking regenerative medicine to a new dimension with a process for guiding nerve cells that could someday help reconnect severed nerve endings.

23 Mar 2004

Stem cell research that could help diabetics

University of Florida adult stem cell experts have restored normal blood sugar levels in diabetic mice for three months by chemically coaxing bone marrow cells to produce insulin, a hormone normally made in the pancreas.

22 Mar 2004

New computer program accurately estimates chance of developing breast cancer

CANCER Research UK scientists have devised a user-friendly computer program, called the IBIS risk evaluator, which can give the most accurate estimate yet of a woman's chance of developing breast cancer.

22 Mar 2004

Tiny Ribozyme package could be future treatment of Hepatitis B virus

Penn State College of Medicine researchers have developed a tiny package that searches for and destroys up to 80 percent of hepatitis B virus in the livers of mice.

22 Mar 2004

Research suggests protein released from lungs could initiate labour

A protein released from the lungs of a developing mouse fetus initiates a cascade of chemical events leading to the mother's initiation of labor, researchers at UT Southwestern Medical Center at Dallas have found.

22 Mar 2004

Risk of kidney stones increases higher if overweight

Researchers at UT Southwestern Medical Center at Dallas have found that the more overweight a person is the more at risk he or she is for forming uric acid kidney stones.

22 Mar 2004

Enzyme Acetylcholinesterase (AChE), New Approach to Drug Design

French and American researchers have developed a unique approach to drug design where an important neuron-signaling enzyme called acetylcholinesterase (AChE) acts as a microscopic vessel filled with reactant chemicals, to create its own, tailored therapeutic agent.

22 Mar 2004

Researchers discover new form of the Rett syndrome protein

Adrian Bird and Skirmantas Kriaucionis of the University of Edinburgh have discovered a novel form of the protein MeCP2. This alternate form, coined MeCP2 alpha, differs from the original only in the first 19 amino acids. Interestingly, Adrian Bird, Director of the Welcome Trust Centre for Cell Biology at Edinburgh University, found that MeCP2 alpha, is ten times more prevalent not only in the brain but also in other tissues. These findings are currently reported online in Nucleic Acids Research. Similar findings were reported yesterday in Nature Genetics online by Berge Minassian, a neurologist and scientist at Toronto's Hospital for Sick Children.

22 Mar 2004

Decreased collagen may make women more susceptible to pelvic organ prolapse

Decreased collagen levels might make some women more susceptible to pelvic organ prolapse and urinary incontinence, according to a new study by physicians at Temple University School of Medicine and Temple University Hospital. The study, “Collagen content of nonsupport tissue in pelvic organ prolapse and stress urinary incontinence,” appears in a recent issue of the American Journal of Obstetrics and Gynecology.

22 Mar 2004

Plasticiser Phthalates connected with rising infertility rates

Phthalates, largely used as plasticisers, have long been suspected in connection with rising infertility rates, particularly among men. These substances are quite common and are considered highly hazardous to human health because they disrupt the hormonal balance and impair reproduction and development. What has not been clear up to now is the amount of phthalates that enter the human body.

22 Mar 2004

Metal-on-metal disc, effective alternative to spinal fusion

The neck and arm pain caused by degenerative cervical (neck) disc disease may be eliminated by replacing the problem disc with a metal-on-metal artificial disc, according to the results of a study presented at the annual meeting of the American Association of Neurological Surgeons/CNS Section on Disorders of the Spine & Peripheral Nerves.

22 Mar 2004